Month: August 2024

U.N. Official Says Criminal Attacks on Gaza Aid Convoys May “Undermine Everything We’re Trying to Do”

(p. 9) A group of Palestinian men approached a United Nations warehouse in central Gaza last week and demanded access to aid stored inside. The gang wasn’t interested in food, fuel or medicine. It wanted something it considered far more valuable: contraband cigarettes hidden in the humanitarian cargo.

The incident, described by a U.N. official, is emblematic of a significant new impediment to aid deliveries in the enclave. Rampant cigarette smuggling—fueled by high prices for tobacco—has become the latest manifestation of a breakdown in law and order that is slowing the delivery of lifesaving assistance.

Aid trucks and storage depots have become targets for Palestinian smugglers seeking to retrieve illicit smokes stashed inside shipments by their accomplices, say U.N. and Israeli officials. Other local criminals are also attacking vehicles they suspect have cigarettes hidden somewhere on board, they say.

Cigarettes sell for as much as $25 apiece in isolated Gaza, so getting hold of even a pack can be enormously profitable.

. . .

Criminal attacks on aid convoys have become so severe that over a thousand truckloads of aid have been left sitting on the Gaza side of the Kerem Shalom border crossing with Israel. Even a daily Israeli pause in fighting along a critical supply route hasn’t been enough to get aid groups to move shipments. “This is threatening to undermine everything we’re trying to do,” a U.N. official said.

For the full story see:

Stephen Kalin, Dov Lieber and Fatima AbdulKarim. “In Gaza, $25 Cigarettes Make Aid Trucks Targets.” The Wall Street Journal (Thursday, June 20, 2024): A7.

(Note: ellipsis added.)

(Note: the online version of the story was updated June 19, 2024, and has the title “At $25 Each, Cigarettes Are Turning Gaza Aid Trucks Into Targets.”)

Pious Climate “Scare Tactics” Lead to Despondency and Bad Policy

(p. A15) Whatever happened to polar bears? They used to be all climate campaigners could talk about, but now they’re essentially absent from headlines. Over the past 20 years, climate activists have elevated various stories of climate catastrophe, then quietly dropped them without apology when the opposing evidence becomes overwhelming. The only constant is the scare tactics.

. . .

After years of misrepresentation, it finally became impossible to ignore the mountain of evidence showing that the global polar-bear population has increased substantially.

. . .

For the past three years the Great Barrier Reef has had more coral cover than at any point since records began in 1986, with 2024 setting a new record.

. . .

Today, killer heat waves are the new climate horror story. In July President Biden claimed “extreme heat is the No. 1 weather-related killer in the United States.”

He is wrong by a factor of 25. While extreme heat kills nearly 6,000 Americans each year, cold kills 152,000, of which 12,000 die from extreme cold. Even including deaths from moderate heat, the toll comes to less than 10,000. Despite rising temperatures, age-standardized extreme-heat deaths have actually declined in the U.S. by almost 10% a decade and globally by even more, largely because the world is growing more prosperous. That allows more people to afford air-conditioners and other technology that protects them from the heat.

. . .

Scare tactics leave everyone—especially young people—distressed and despondent. Fear leads to poor policy choices that further frustrate the public. And the ever-changing narrative of disasters erodes public trust.

Telling half-truths while piously pretending to “follow the science” benefits activists with their fundraising, generates clicks for media outlets, and helps climate-concerned politicians rally their bases. But it leaves all of us poorly informed and worse off.

For the full commentary see:

Bjorn Lomborg. “Polar Bears, Dead Coral and Other Climate Fictions.” The Wall Street Journal (Thursday, Aug. 1, 2024): A15.

(Note: ellipses added.)

(Note: the online version of the commentary has the date July 31, 2024, and has the same title as the print version.)

In “An Entrenched Echo Chamber” the Highly Credentialed Slow Progress Toward an Alzheimer’s Cure

Centralized research funding (often centralized by government agencies) reduces the pluralism of ideas and methods that often lead to breakthrough innovations. The story of Alzheimer’s research, quoted below, is a dramatic case-in-point.

A secondary related lesson from the story quoted below is that Dr. Thambisetty, one of the outsiders struggling to make a difference, is trying to evade the enormous costs of mandated phase 3 clinical trials, by only investigating drugs that already have been approved by the FDA for use against other conditions. With his severely limited funding, and the huge costs of mandated phase 3 clinical trials, this may be a shrewd strategy for Thambisetty, but notice that by following it, he will never explore all the as-yet-unapproved chemicals that might include the best magic bullet against Alzheimer’s.)

(p. A25) What if a preposterous failed treatment for Covid-19 — the arthritis drug hydroxychloroquine — could successfully treat another dreaded disease, Alzheimer’s?

Dr. Madhav Thambisetty, a neurologist at the National Institute on Aging, thinks the drug’s suppression of inflammation, commonly associated with neurodegenerative disorders, might provide surprising benefits for dementia.

It’s an intriguing idea. Unfortunately, we won’t know for quite a while, if ever, whether Dr. Thambisetty is right. That’s because unconventional ideas that do not offer fealty to the dominant approach to study and treat Alzheimer’s — what’s known as the amyloid hypothesis — often find themselves starved for funds and scientific mind share.

Such shortsighted rigidity may have slowed progress toward a cure — a tragedy for a disease projected to affect more than 11 million people in the United States by 2040.

. . .

. . ., in 2006, an animal experiment published in the journal Nature identified a specific type of amyloid protein as the first substance found in brain tissue to directly cause symptoms associated with Alzheimer’s. Top scientists called it a breakthrough that provided a key target for treatments. The paper became one of the most cited in the field, and funds to explore similar proteins skyrocketed.

. . .

In 2022, my investigation in Science showed evidence that the famous 2006 experiment that helped push forward the amyloid hypothesis used falsified data. On June 24 [2024], after most of its authors conceded technical images were doctored, the paper was finally retracted.

. . .

In reporting for my forthcoming book about the disturbing state of play in Alzheimer’s research, I’ve spoken to many scientists pursuing alternatives. Dr. Thambisetty, for example, compares brain tissues from people who died in their 30s or 40s with and without genetic risk factors for Alzheimer’s. He then compares these findings to tissues from deceased Alzheimer’s patients and people who didn’t have the disease. Where changes overlap, drug targets might emerge. Rather than develop new drugs through lab and animal testing, followed by clinical trials that cost vast sums — a process that can take decades — he examines treatments already approved as reasonably safe and effective for other conditions. Patent protections have lapsed for many, making them inexpensive.

Experiments have also begun to test the weight-loss drug semaglutide (sold as Wegovy, among other brands). Researchers hope that results due in 2026 will show that its anti-inflammatory effects — like Dr. Thambisetty’s idea about hydroxychloroquine — slow cognitive decline.

Ruth Itzhaki, a research scientist at the University of Oxford, stirred curiosity in the 1990s when she shared evidence tying Alzheimer’s to herpesvirus — a scourge spread by oral or genital contact and often resulting in painful infections. For years, powerful promoters of the amyloid hypothesis ignored or dismissed the infection hypothesis for Alzheimer’s, effectively rendering it invisible, Dr. Itzhaki said with exasperation. Research suggests that viruses may hide undetected in organs, including the brain, for years, causing symptoms divergent from the original infection.

. . .

Sometimes a disease stems from a single clear-cut origin, such as genetic mutations that cause deadly sickle cell disease. “But very few diseases of aging have just one cause. It’s just not logical,” said Dr. Matthew Schrag, a neurologist at Vanderbilt University Medical Center. Working independently of his university, he discovered the 2006 research image manipulations.

. . .

“There is an entrenched echo chamber that involves a lot of big names,” Dr. Schrag said. “It’s time for the field to move on.”

For the full commentary see:

Charles Piller. “All the Alzheimer’s Research We Didn’t Do.” The New York Times (Friday, July 12, 2024): A25.

(Note: ellipses, and bracketed year, added.)

(Note: the online version of the commentary has the date July 7, 2024, and has the same title as the print version. Where there are a couple of small differences in wording, the passages quoted above follow the online version.)

Piller’s paper in Science, mentioned above, is:

Piller, Charles. “Blots on a Field?” Science 377, no. 6604 (July 2022): 358-63.

Piller’s commentary is related to his forthcoming book:

Piller, Charles. Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s. New York: Atria/One Signal Publishers, Forthcoming on February 4, 2025.

“Heavily Subsidized Renewables” Mostly Add to Total Energy Consumed Instead of Replacing Fossil Fuels

(p. A17) Despite extravagant hype, the green-energy transition from fossil fuels isn’t happening. Achieving a meaningful shift with current policies is too costly. We need to change policy direction entirely.

. . .

Studies show that when countries add more renewable energy, it does little to replace coal, gas or oil. It simply adds to energy consumption. Recent research shows that for every six units of green energy, less than one unit displaces fossil-fuel energy. The Biden administration finds that while renewable energy sources worldwide will dramatically increase up to 2050, that won’t be enough even to begin replacing fossil fuels—oil, gas and coal will all keep increasing, too.

. . .

The current plan underpinning the green-energy transition mostly insists that pushing heavily subsidized renewables will magically make fossil fuels disappear. But such expectations are “misleading,” as a 2019 academic study concluded. During past additions of a new energy source, the researchers found, it has been “entirely unprecedented for these additions to cause a sustained decline in the use of established energy sources.”

What causes us to change our relative use of energy? One study investigated 14 shifts that happened over the past five centuries, such as when farmers went from plowing fields with animals to tractors powered by fossil fuels. Invariably, the new energy source would be better or cheaper.

. . .

The way to achieve an eventual transition is to improve green-energy alternatives. That means investing much more in research and development. Innovation is needed in wind and solar, as well as storage, nuclear energy, and other possible solutions. Bringing the costs of low-CO2₂energy sources below those of fossil fuels is the only way that green solutions can be implemented globally, and not merely by a few wealthy countries.

When politicians say the green transition is here, they are really asking voters to support throwing more good money after bad. We need to be smarter.

For the full commentary see:

Bjorn Lomborg. “The ‘Green Energy Transition’ That Wasn’t.” The Wall Street Journal (Tuesday, June 25, 2024): A17.

(Note: ellipses added.)

(Note: the online version of the commentary has the date June 24, 2024, and has the same title as the print version.)

The “recent research” mentioned above is:

Rather, Kashif Nesar, and Mantu Kumar Mahalik. “Investigating the Assumption of Perfect Displacement for Global Energy Transition: Panel Evidence from 73 Economies.” Clean Technologies and Environmental Policy (2023) https://doi.org/10.1007/s10098-023-02689-8.

The “2019 academic study” mentioned above is:

York, Richard, and Shannon Elizabeth Bell. “Energy Transitions or Additions?: Why a Transition from Fossil Fuels Requires More Than the Growth of Renewable Energy.” Energy Research & Social Science 51 (May 2019): 40-43.

The study of 14 shifts in type of energy that was mentioned above is:

Fouquet, Roger. “The Slow Search for Solutions: Lessons from Historical Energy Transitions by Sector and Service.” Energy Policy 38, no. 11 (Nov. 2010): 6586-96.

“Large Citizen Science Projects” Use Data Mining to Explore Risk Factors for Canine Cancers

(p. 2) Every dog has its day, and July 14, 2004, belonged to a boxer named Tasha. On that date, the National Institutes of Health announced that the barrel-chested, generously jowled canine had become the first dog to have her complete genome sequenced. “And everything has kind of exploded since then,” said Elaine Ostrander, a canine genomics expert at the National Human Genome Research Institute, who was part of the research team.

. . .

In the 2000s, scientists identified the genetic underpinnings of a variety of canine traits, including curly coats and bobbed tails. They pinpointed mutations that could explain why white boxers were prone to deafness. And they found that corgis, basset hounds and dachshunds owed their stubby legs to a genetic aberration in a family of genes that also regulates bone development in humans.

These early studies “highlighted both the potential that we could learn from dogs, but also that we were going to need bigger sample sizes to do it really well,” said Elinor Karlsson, a geneticist at UMass Chan Medical School and the Broad Institute. And so, researchers began creating large citizen science projects, seeking DNA samples and data from dogs across the United States.

Pet owners rose to the challenge. The Golden Retriever Lifetime Study, which began recruiting in 2012, has been following more than 3,000 dogs in an effort to identify genetic and environmental risk factors for cancer, which is especially common in the breed. Since 2019, the Dog Aging Project, a long-term study of health and longevity, has enrolled nearly 50,000 dogs.

Dr. Karlsson’s own project, Darwin’s Dogs, is at 44,000 canines and counting. (Some 4,000 have had their genomes sequenced.) Researchers are mining the data for clues about bone cancer, compulsive behavior and other traits.

For the full story see:

Emily Anthes. “Scientists’ New Best Friends.” The New York Times, Pets Special Section (Sunday, June 30, 2024): 2.

(Note: ellipsis added.)

(Note: the online version of the story has the same date as the print version, and has the title “How Science Went to the Dogs (and Cats).”)

Israel’s Version of Reagan’s Missile-Defense System Protected Against Iran’s Barrage

(p. A13) Allow me to identify who saved the people of Israel last weekend from Iran’s missile barrage: Ronald Reagan.

In 1983, President Reagan in a televised speech proposed what he called the Strategic Defense Initiative. Its core idea was that the U.S. would build defense systems that could shoot down nuclear-armed ballistic missiles, then expected to be fired by the Soviet Union at the U.S. mainland.

Democrats and much of the defense establishment mocked the idea, with Sen. Ted Kennedy naming it “Star Wars.”

. . .

By universal acclamation, the hero of last weekend was Israel’s missile-defense systems. The world watched in real time Saturday night as Reagan’s commitment to shooting down missiles protected Israel’s population from the more than 300 drones and ballistic and cruise missiles fired by Iran and its proxies at cities across Israel.

No nation more quickly recognized the necessity of missile defenses than Israel, a small, population-packed country that couldn’t afford the conceit of some U.S. politicians, then and today, that the American landmass is somehow safe from missile attacks. Within two years of Reagan’s announcement, Israel signed a memorandum of understanding with the U.S. to develop missile defenses. The fruits of that four-decade partnership couldn’t be clearer.

. . .

Reagan’s missile-defense legacy does have an important advocate: Donald Trump. As president in 2019, Mr. Trump revived the U.S. missile-defense program, and he restated that commitment, citing Reagan, during this year’s New Hampshire primary.

For the full story see:

Daniel Henninger. “WONDER LAND; Reagan Just Saved Israel.” The Wall Street Journal (Thursday, April 17, 2024): A13.

(Note: ellipses added.)

(Note: the online version of the story has the date April 18, 2024, and has the title “WONDER LAND; Ronald Reagan Just Saved Israel From Iran’s Attack.”)

Black American Woman Professor of Cinema Says “You Can Love” Gone with the Wind

(p. C5) The handsome Tudor Revival mansion set on a shaded lot in the bustling heart of Atlanta has long been known as the Margaret Mitchell House. Yet, in truth, Mitchell’s time there — a span of seven years, during which she wrote “Gone With the Wind” — was confined to a 650-square-foot first-floor apartment she so lovingly named “The Dump.”

Over time, Mitchell and the property she never owned would become inextricable. Visitors wanted to step into the cramped quarters where Mitchell, an unemployed former newspaper reporter, created a sprawling saga that came to define the antebellum South in the popular imagination.

. . .

“We’re not trying to label her,” said Sheffield Hale, the president and chief executive of Atlanta History Center, the museum and research center that has overseen operations of the house since 2004. “We’re not trying to praise or denigrate her. There’s a whole lot of non-Confederate gray in this exhibit.”

. . .

. . ., the director John Ridley, the screenwriter behind the 2013 Oscar-winning film “12 Years a Slave,” wrote an essay in The Los Angeles Times in which he urged the streamer HBO Max to remove the film from its platform before reintroducing it with more context for viewers.

“The movie had the very best talents in Hollywood at that time working together to sentimentalize a history that never was,” he wrote.

HBO acquiesced, pulling the film and then restoring it with a four-minute introduction that outlined its value and its flaws, and an explanation of why suppressing the film was not the right solution.

. . .

The book, published in 1936, was a critical and commercial success, winning a Pulitzer Prize and selling nearly a million copies within six months. Readers were enthralled with the travails of the protagonist, Scarlett O’Hara, from the start of the Civil War through the turmoil of Reconstruction.

“People had been dealing with really hard times,” Haley said, referring to the Great Depression. She added, “The story is about redemption and it’s about a character going through a war and coming out on the other side and ‘Never be hungry again.’”

. . .

. . . for all of the reappraising, visitors may come away with the sense that both the pride and the pain the story inspired were justified, said Stephane Dunn, a professor of cinema, television and emerging media studies at Morehouse College in Atlanta, who advised the exhibit’s curators.

“You can love it,” Dunn said.

She still does.

“I mean, I am a Black American woman, right?” she said. “I did not think slavery was romantic, but I found Scarlett fascinating. I found the costumes fascinating. I found in Mammy her strength, and she was not invisible in any scene she was in.”

“Gone With the Wind” has waned in popularity as an understanding of American history has evolved. But by the time visitors reach the end of the exhibit, organizers said, the hope is that they will understand how the story came to be and why it resonated.

“Because that helps us look at the stories we’re telling today,” Haley said, “to see if there are areas where we could stand to expand our perspectives.”

For the full story see:

Rick Rojas. “Pride and Pain Under One Roof.” The New York Times (Saturday, July 13, 2024): C5.

(Note: ellipses added.)

(Note: the online version of the story has the date July 12, 2024, and has the title “At Margaret Mitchell’s House, ‘Gone With the Wind’ Gets a Rewrite.”)

The book is:

Mitchell, Margaret. Gone with the Wind. New York: Vintage Classics, 2020 (1st ed. 1936).

Ondrasik Sings in Support of Israel’s Fight “For Freedom, Democracy, Life, Civilization”

(p. A11) The music industry loves a good cause. Band Aid, Live Aid, Farm Aid, Stand Up to Cancer, Hope for Haiti, the Concert for Sandy Relief, the Concert for Ukraine—when the issue is potent enough, big-name musicians from every genre will come, and usually perform for free. All they typically want is to show the world how much they care.

The ability to shine a light on issues and causes that matter is a perk of fame. For John Ondrasik, right now, that’s Israel. The Grammy-nominated American singer and musician, who goes by the nom de chanson Five for Fighting, has been steadfast and outspoken about the Jewish state’s security needs since the Oct. 7 attacks. This has made him a unicorn among his music-industry peers. Most prefer simply to keep their heads down.

. . .

Mr. Ondrasik, 59, isn’t keeping his head down. He appears on Fox News and on Mark Levin’s radio show. He’s aggressive on Twitter in support of Israel. He is, as his stage name suggests, something of a brawler. On April 13 [2024], the night before Iran launched a barrage of missiles and drones at Israel, he performed at an outdoor concert in Tel Aviv and condemned “the evil that is Hamas.” He sang his Oct. 7-themed song, “OK”—the refrain is “We are not OK”—for the families of hostages still in Gaza.

“Why are you doing this?” Mr. Ondrasik says people always want to know. He isn’t Jewish. He doesn’t have relatives in Israel. He’s from Southern California and his heritage is Slovak. But, he says, “I’m human.” In Tel Aviv he told the crowd, “One doesn’t have to be Jewish to support Israel in their fight—sorry, our fight—for freedom, democracy, life, civilization, against those who want to tear it down.”

. . .

The left-right dynamic infuriates Mr. Ondrasik: “It’s not political. It shouldn’t be.” He says his support for Israel derives from the same impulse that led him to champion Ukraine in its fight for survival against Russia. They are both free nations fighting to preserve the Western values of democracy and human rights against those who would replace them with tyranny.

For the full interview see:

Matthew Hennessey. “THE WEEKEND INTERVIEW; A Lone Voice Sings for Israel.” The Wall Street Journal (Saturday, April 27, 2024): A11.

(Note: ellipses, and bracketed year, added; some words in the original were italicized, but the format of this blog does not allow that to be distinguished.)

(Note: the online version of the interview has the date April 26, 2024, and has the title “THE WEEKEND INTERVIEW; Five for Fighting: A Lone Voice Sings for Israel.”)

Climate-Change-Induced Flooding Blamed for Hurting Tiny Flowers, Instead Helped Them “Flourish”

(p. A10) The whimsical image fit when the state of Vermont announced last month that a plant thought to be locally extinct — false mermaid-weed — had been found through a chain of events that seemed stolen from a fairy tale.

It began with a sharp-eyed turtle biologist for the state, Molly Parren. She had been out surveying the habitat of wood turtles in rural Addison County on May 7 [2024] when she spotted some wild meadow garlic, which is extremely rare, beside a stream. Ms. Parren snapped a photo and sent it to her colleague, Grace Glynn, Vermont’s state botanist.

But when Ms. Glynn opened the photo, another plant, visible in the foreground, seized her attention. She knew at once what it was: Floerkea proserpinacoides, or false mermaid-weed, an herb that had not been documented in Vermont for more than a century, and one that Ms. Glynn had sought in vain for years.

. . .

The day after the false mermaid-weed was spotted, Ms. Glynn rushed to the rural site to confirm its presence in person. She found a dense carpet — “so many plants, it was hard to imagine how they had been overlooked,” she said.

And yet her disbelief was familiar. “It happens a lot, people saying, ‘We couldn’t have missed that,’” she said. “But we do, and we’re humbled over and over — I love that.”

Far from an anomaly, rediscoveries of plants thought to be extinct are a relatively regular feature of field botany.

. . .

Tricky as it is to find elusive species, it is harder to pinpoint why they thrive or dwindle, and how such shifts might be related to a changing climate. Flooding is cited as one possible factor in the disappearance of false mermaid-weed from Vermont. And yet flooding in the state last summer may have helped it flourish by the stream where it was found, Ms. Glynn said, by depositing sediment and creating a more hospitable habitat.

For the full story see:

Jenna Russell. “By a Stream in Vermont, Rediscovering a Plant Last Seen a Century Ago.” The New York Times (Friday, June 14, 2024): A10.

(Note: ellipses, and bracketed year, added.)

(Note: the online version of the story has the date June 11, 2024, and has the title “By a Stream in Vermont, a Glimpse of a Plant Last Seen a Century Ago.”)