Those Who Criticize the Powerful “Are Seldom Seen Distinctly by the Age in Which They Live”

Founding Father Benjamin Rush was apparently willing to take the ill-will that comes to those who challenge the lazy, incompetent, or corrupt.

The importance of being willing to be the target of ill-will was well-described by Charlie Munger.

(p. C7) During the spring of 1813, former presidents John Adams and Thomas Jefferson were united in grief at the death of a mutual friend who had recently persuaded them to forget their bitter rivalries. Like the two celebrated statesmen, the eminent physician and social reformer Benjamin Rush had been a Founding Father, one of 56 men who signed the Declaration of Independence in 1776.

. . .

. . ., after George Washington’s beaten army was pushed back across the Delaware River and Philadelphia’s militia marched to his assistance, Rush volunteered his medical skills. He helped tend the wounded from the Second Battle of Trenton, on Jan. 2, 1777, and the next day witnessed the bloody aftermath of Washington’s victory at Princeton.

Months later, Rush was appointed surgeon-general of the Continental Army’s so-called Middle Department—a key geographical sector that included Pennsylvania. He had ambitious plans for reform and outlined them in a pamphlet titled “Directions for Preserving the Health of Soldiers.” In a statement true for future American wars, he observed: “A greater proportion of men have perished with sickness in our armies than have fallen by the sword.” To curb that toll, Rush urged radical changes in food, clothing and hygiene. In his improving zeal, he unleashed a barrage of unrestrained letters to his friends in Congress that swiftly kindled a feud with his superior, Dr. William Shippen.

Rush accused Shippen of neglect, incompetence and corruption but underestimated his antagonist’s political clout.

. . .

(p. C8) . . ., Rush himself had always suspected that his outspoken views would affect his reputation, observing: “The most acceptable men in practical society, have been those who have never shocked their contemporaries, by opposing popular or common opinions.” He added, with considerable prescience: “Men of opposite characters, like objects placed too near the eye, are seldom seen distinctly by the age in which they live.” Through the efforts of Mr. Fried and Mr. Unger, what Benjamin Rush characterized as “the distant and more enlightened generations” are now better placed to judge him.

For the full review see:

Stephen Brumwell. “American Hippocrates.” The Wall Street Journal (Saturday, May 20, 2017 [sic]): C7-C8.

(Note: ellipses added.)

(Note: the online version of the review has the date Sept. 20, 2018 [sic], and has the title “‘Rush’ and ‘Dr. Benjamin Rush’ Review: American Hippocrates.”)

The books under review are:

Fried, Stephen. Rush: Revolution, Madness, and Benjamin Rush, the Visionary Doctor Who Became a Founding Father. New York: Crown, 2018.

Unger, Harlow Giles. Dr. Benjamin Rush: The Founding Father Who Healed a Wounded Nation. New York: Da Capo Press, 2018.

F.D.R.’s Wage Controls Created a Wedge Between Patients and Doctors, With Awful Unintended Consequences

Under F.D.R.’s wage controls, firms competed for workers through perks, like healthcare benefits, since they could not legally compete by offering higher wages. That resulted in the first middlemen (in this case firms) between the customers (patients) and the suppliers (doctors). The result of adding the middlemen, and also adding a variety of regulations, is a “market” that is opaque, inefficient, and slow to innovate. Rather than drain the swamp, the response has been to add more middlemen (Medicare, Medicaid, Obamacare, and Pharmacy Benefit Managers, aka PBMs), that have only thickened the mire.

(p. B11) The roots of today’s fragmented system can be traced back to a quirk in U.S. history. Unlike most high-income countries, which created centralized government systems to ration care in the 20th century, the U.S. followed a different path shaped by historical circumstances. During World War II, wage controls prompted employers to offer health insurance as a tax-free benefit to attract workers.

Medicare and Medicaid, followed decades later by Affordable Care Act exchanges, were added over time to cover those who couldn’t get insurance through their job, creating a highly decentralized and convoluted system.  . . .

. . . the pressure to increase their earnings means insurers have looked for ways to overbill the government and skimp on patient care, always staying a step ahead of regulators. In recent years, they have become vertically integrated conglomerates, controlling doctors, pharmacies and payment-processing systems.

. . .

One of the most frustrating aspects of the system is a tactic called prior authorization, a process requiring providers to obtain insurer approval before delivering certain services. While that might be disagreeable, there is little public data on how often insurers deny care. This lack of transparency allows insurers to wield prior authorization aggressively, particularly when expensive treatments are recommended.

For the full commentary see:

David Wainer. “How to Fix Health Insurance.” The Wall Street Journal (Saturday, Dec. 21, 2024): B11.

(Note: ellipses added.)

(Note: the online version of the commentary has the date December 20, 2024, and has the title “How American Health Insurance Got So Infuriating.”)

In Europe Citizens Self-Medicated with Coca Plant Before Official Use in Hospital

Bones from the 1600s in a hospital crypt reveal the use of coca leaves, even though the records from the hospital do not record any use of coca leaves. The records do indicate the early use of derivatives of the opium poppy plant, so if coca leaves were being officially used, you would expect that would also be in the records. One of the researchers, Cristina Cattaneo, concludes that the coca plant was not an official medicine but was “something lurking among the population” (as quoted in Nazaryan 2024, p. D3).

The findings of Giordano are summarized in:

Alexander Nazaryan. “Cocaine Use in Europe Is Dated to the 1600s.” The New York Times (Tues., September 17, 2024): D3.

(Note: the online version of the Steve Lohr article was updated Sept. 13, 2024, and has the title “Europeans Used Cocaine Much Earlier Than Previously Thought, Study Finds.”)

The academic paper co-authored by Cattaneo is:

Giordano, Gaia, Mirko Mattia, Lucie Biehler‐Gomez, Michele Boracchi, Alessandro Porro, Francesco Sardanelli, Fabrizio Slavazzi, Paolo Maria Galimberti, Domenico Di Candia, and Cristina Cattaneo. “Forensic Toxicology Backdates the Use of Coca Plant (Erythroxylum Spp.) in Europe to the Early 1600s.” Journal of Archaeological Science 170 (Oct. 2024): 106040.

An earlier related academic paper, on evidence of early official use of derivatives of the opium poppy, is:

Giordano, Gaia, Mirko Mattia, Lucie Biehler-Gomez, Michele Boracchi, Stefania Tritella, Emanuela Maderna, Alessandro Porro, Massimiliano Marco Corsi Romanelli, Antonia Francesca Franchini, Paolo Maria Galimberti, Fabrizio Slavazzi, Francesco Sardanelli, Domenico Di Candia, and Cristina Cattaneo. “Papaver Somniferum in Seventeenth Century (Italy): Archaeotoxicological Study on Brain and Bone Samples in Patients from a Hospital in Milan.” Scientific Reports 13, no. 1 (2023): 3390.

For Quicker Cures, Do Not Cancel Those Who See What We Do Not See

Dogs smell odors that we do not smell. They say Eskimos can distinguish 40 or more kinds of snow. Physical differences in biology and differences in past experiences allow some people to perceive what other people miss. We should encourage, not cancel, those who see differently. They can communicate and act on what they see, giving us more cures more quickly.

In the passages quoted below, a case is made that Pasteur’s artistic experiences allowed him to see a structural difference (chirality) in crystals; a difference that turns out to matter for medical drug molecules.

(p. D5) In a paper published last month in Nature Chemistry, Dr. Gal explains how a young Pasteur fought against the odds to articulate the existence of chirality, or the way that some molecules exist in mirror-image forms capable of producing very different effects. Today we see chirality’s effects in light, in chemistry and in the body — even in the drugs we take.

And we might not know a thing about them if it weren’t for the little-known artistic experience of Louis Pasteur, says Dr. Gal.

. . .

As a teenager, Pasteur made portraits of his friends, family and dignitaries. But after his father urged him to pursue a more serious profession — one that would feed him — he became a scientist. At the age of 24 he discovered chirality.

To understand chirality, consider two objects held up before a mirror: a white cue ball from a pool table and your hand. The reflection of the ball is exactly like the original. If you could reach into that mirror, pull out the reflection and cram it inside the original, they’d match up point for point. But if you tried the same thing with your hand, no matter how much you tried, the mirror image would never fit into the original.

At the molecular level some objects are like cue balls, and they are always superimposable. But other things are like hands, and they can never be combined.

. . .

During winemaking, a chemical called tartaric acid builds up on vat walls. In the 18th and 19th centuries, makers of medicine and dyes used this acid.

In 1819, factory workers boiled wine too long and accidentally produced paratartaric acid, which had unique properties that intrigued scientists like Pasteur.

. . .

When studying the paratartaric acid, Pasteur found that it produced two kinds of crystals — one like those found in tartaric acid and another that was the mirror opposite. The crystals were handed, or what the Greeks call chiral (kheir) for hand.

. . .

“Several famous or much more accomplished scientists, some well along their illustrious careers, studied the same molecules, the same substances,” said Dr. Gal. “Realistically you would think they’d have beaten him to the punch, and yet they missed it.”

So why did this young, inexperienced chemist get it right?

Dr. Gal thinks the answer might lie in the artistic passions of Pasteur’s youth. Even as a scientist, Pasteur remained closely connected to art. He taught classes on how chemistry could be used in fine art and attended salons. He even carried around a notebook, jotting down 1-4 ratings of artwork he visited.

And then Dr. Gal stumbled upon a letter Pasteur had written to his parents about a lithographic portrait he had made of a friend.

Lithography back then involved etching a drawing onto a limestone slab with wax or oil and acid, and pressing a white piece of paper on top of it. The resulting picture was transposed, like a mirror image of the drawing left on the slab.

In his letter, Pasteur wrote:

“I think I have not previously produced anything as well drawn and having as good a resemblance. All who have seen it find it striking. But I greatly fear one thing, that is, that on the paper the portrait will not be as good as on the stone; this is what always happens.”

Eureka. “Isn’t this the explanation of how he saw the handedness on the crystals — because he was sensitized to that as an artist?” Dr. Gal proposed.

. . .

We now know that many drugs contain molecules that exist in two chiral forms, and that the two forms can react differently in the body. The most tragic example occurred in the 1950s and ’60s, when doctors prescribed Thalidomide, a drug for morning sickness and other ailments, to pregnant women. The drug also contained a chiral molecule that caused disastrous side effects in many babies.

For the full story see:

Joanna Klein. “How Pasteur’s Artistic Insight Changed Chemistry.” The New York Times (Tuesday, June 20, 2017 [sic]): D5.

(Note: ellipses added.)

(Note: the online version of the story has the date June 14, 2017 [sic], and has the same title as the print version.)

The academic article in Nature Chemistry authored by Gal and mentioned above is:

Gal, Joseph. “Pasteur and the Art of Chirality.” Nature Chemistry 9, no. 7 (2017): 604-05.

See also:

Vantomme, Ghislaine, and Jeanne Crassous. “Pasteur and Chirality: A Story of How Serendipity Favors the Prepared Minds.” Chirality 33, no. 10 (2021): 597-601.

Peppermint at One Time Required a Prescription, While Strychnine Was Sold Over-the-Counter

I suspect I would not much like the Remaking the American Patient book–it seems to blame capitalism for all of the ills of the healthcare system. But it does include one compelling example of the limitations of government regulation of drugs: allowing strychnine while restricting peppermint.

(p. D3) Medical historians who focus on the conquest of dire diseases serve up narratives of progress and triumph. Not Ms. Tomes, a professor of history at Stony Brook University, who has chosen to examine instead the health care experience of average healthy citizens, the great silent majority whose lives are punctuated by a variety of minor ills and only the occasional major calamity.

. . .

Are you perplexed by our regulatory chaos, with layer upon layer of well-meaning but persistently ineffective efforts to guarantee the safety of medical services? It turns out we come from a long tradition of such inadequacy: Patient safety has been the holy grail for everyone, long sought, never achieved.

Drug regulatory efforts have been inconsistent and confusing. (At one point in the 1940s, peppermint drops were available by prescription, while strychnine could be freely purchased by anyone).

For the full review see:

Abigail Zuger, M.D. “When Patients Became Purchasers.” The New York Times (Tuesday, January 26, 2016 [sic]): D3.

(Note: ellipsis added.)

(Note: the online version of the review has the date Jan. 23, 2016 [sic], and has the title “Review: ‘Remaking the American Patient’.”)

The book under review above is:

Tomes, Nancy. Remaking the American Patient: How Madison Avenue and Modern Medicine Turned Patients into Consumers, Studies in Social Medicine. Chapel Hill: The University of North Carolina Press, 2016.

In Middle Ages the Less Credentialed Offered “Daily Care,” While “Experts” Theorized

(p. 12) A new book about medieval views on medicine helps explain the Oby nuns’ contentment with the cheapness of their lives. In “Medieval Bodies: Life and Death in the Middle Ages,” the British art historian Jack Hartnell tackles a difficult phenomenon: the medieval embrace of medical “theories that have since been totally disproven to the point of absurdity but which nevertheless could not have seemed more vivid or logical in the Middle Ages.”

The doctors of Europe and the Mediterranean were not practical specialists but rather scholars of Greek and Roman natural philosophy, which taught a theory of nature composed of four basic elements (fire, water, earth, air). Each was associated with differing levels of moisture and heat. The human body contained four viscous liquids or “humors”: phlegm, blood, yellow bile and black bile. A doctor’s job was to correct an uneven humoral balance, drying up perceived wetness with spices or relieving an excess of heat with cooling herbs.

While experts promulgated theory, daily care was mostly administered by midwives, apothecaries, dentists and the odd entrepreneurial carpenter. A local barber might puncture your neck to drain three pints of blood if you complained of a headache.

For the full review see:

Josephine Livingstone. “Death by a Thousand Cuts.” The New York Times Book Review (Sunday, January 5, 2020 [sic]): 12.

(Note: the online version of the review has the date Nov. 19, 2019 [sic], and has the title “Bad Bishops, Bloodletting and a Plague of Caterpillars.”)

The book under review is:

Hartnell, Jack. Medieval Bodies: Life and Death in the Middle Ages. New York: W. W. Norton & Company, 2019.

Not All Indians Were Peaceful Saints

The scalp of William Thompson. Source of photo: Omaha Public Library.

As I child I played cowboys and Indians. We used to fire the fake rifles at the frontier fort on Tom Sawyer Island in Disneyland. Today you cannot do that since it is politically correct to believe that before the arrival of universally evil Europeans all Indians were peace-loving environmentalists. The belief is false. But The Walt Disney Company in California has bought the falsehood, closing the Disneyland frontier fort so that children can no longer pretend to defend civilization. (In Florida, where civilization yet survives, The Walt Disney Company still allows children to play in the Magic Kingdom version of the frontier fort.)

(p. E1) I’m leading off with my nomination for the most bizarre item ever exhibited in Omaha. It’s been around for more than 150 years, and it’s a shame if you haven’t seen it–that is, as long as you’re not too squeamish It used to belong to William Thompson, an Englishman who was employed by Union Pacific on the new transcontinental railroad.

In 1867, while working at Plum Creek Station, near Lexington, Nebraska, Thompson was scalped by a band of the Northern Cheyenne. He was left for dead, but when he recovered consciousness, he found his scalp not far away. Remarkably, he put it in a bucker of salt water and headed to Omaha on a rescue train. On arrival he asked Dr. Richard Moore to reattach it. That wasn’t possible, so he kept it as a souvenir. Later he gave the preserved scalp to Moore, who donated it to the Omaha Public Library in 1900. Since then, it has been exhibited from time to time at both the old Union Pacific Museum and the main library. OPL took it off public exhibit in 1977, but it made a surprise appearance in 2012 for the library’s 140th anniversary celebration. I am grateful to library specialist Lynn Sullivan for a private showing last year of the desiccated scalp, complete with a nice shock of sandy-orange hair.

For the full story see:

Marks, Bob. “Weird, Wild and Wonderful Exhibits Here.” Omaha World-Herald (Sunday, March 21, 2024): E1-E2.

During Black Death Only 7 of 21 Regions of Europe Had Catastrophic Decline in Agricultural Activity

(p. D4) In the mid-1300s, a species of bacteria spread by fleas and rats swept across Asia and Europe, causing deadly cases of bubonic plague. The “Black Death” is one of the most notorious pandemics in historical memory, with many experts estimating that it killed roughly 50 million Europeans, the majority of people across the continent.

“The data is sufficiently widespread and numerous to make it likely that the Black Death swept away around 60 percent of Europe’s population,” Ole Benedictow, a Norwegian historian and one of the leading experts on the plague, wrote in 2005. When Dr. Benedictow published “The Complete History of the Black Death” in 2021, he raised that estimate to 65 percent.

But those figures, based on historical documents from the time, greatly overestimate the true toll of the plague, according to a study published on Thursday [Feb. 10, 2022]. By analyzing ancient deposits of pollen as markers of agricultural activity, researchers from Germany found that the Black Death caused a patchwork of destruction. Some regions of Europe did indeed suffer devastating losses, but other regions held stable, and some even boomed.

. . .

Losing half the population would have turned many farms fallow. Without enough herders to tend livestock, pastures would have become overgrown. Shrubs and trees would have taken over, eventually replaced by mature forests.

If the Black Death did indeed cause such a shift, Dr. Izdebski and his colleagues reasoned, they should be able to see it in the species of pollen that survived from the Middle Ages. Every year, plants release vast amounts of pollen into the air, and some of it ends up on the bottom of lakes and wetlands. Buried in the mud, the grains can survive sometimes for centuries.

To see what pollen had to say about the Black Death, Dr. Izdebski and his colleagues picked out 261 sites across Europe — from Ireland and Spain in the west to Greece and Lithuania in the east — that held grains preserved from around 1250 to 1450.

In some regions, such as Greece and central Italy, the pollen told a story of devastation. Pollen from crops like wheat dwindled. Dandelions and other flowers in pastureland faded. Fast-growing trees like birch appeared, followed by slow-growing ones like oaks.

But that was hardly the rule across Europe. In fact, just seven out of 21 regions the researchers studied underwent a catastrophic shift. In other places, the pollen registered little change at all.

. . .

Monica Green, an independent historian based in Phoenix, speculated that the Black Death might have been caused by two strains of the bacteria Yersinia pestis, which could have caused different levels of devastation. Yersinia DNA collected from medieval skeletons hints at this possibility, she said.

In their study, Dr. Izdebski and his colleagues did not examine that possibility, but they did consider a number of other factors, including the climate and density of populations in different parts of Europe. But none accounted for the pattern they found.

“There is no simple explanation behind that, or even a combination of simple explanations,” Dr. Izdebski said.

. . .

“What we show is that there are a number of factors, and it’s not easy to predict from the beginning which factors will matter,” he said, referring to how viruses can spread. “You cannot assume one mechanism to work everywhere the same way.”

For the full essay see:

Carl Zimmer. “Questioning the Toll Of a 1300s Pandemic.” The New York Times (Tuesday, February 15, 2022 [sic]): D4.

(Note: ellipses, and bracketed date, added.)

(Note: the online version of the essay was updated Feb. 15, 2022 [sic], and has the title “Did the ‘Black Death’ Really Kill Half of Europe? New Research Says No.”)

The book cited above as over-estimating the death toll of the Black Death is:

Benedictow, Ole J. The Complete History of the Black Death. Martlesham, UK: Boydell Press, 2021.

The academic article co-authored by Izdebski and mentioned above is:

Izdebski, A., P. Guzowski, R. Poniat, L. Masci, J. Palli, C. Vignola, M. Bauch, C. Cocozza, R. Fernandes, F. C. Ljungqvist, T. Newfield, A. Seim, D. Abel-Schaad, F. Alba-Sánchez, L. Björkman, A. Brauer, A. Brown, S. Czerwiński, A. Ejarque, M. Fiłoc, A. Florenzano, E. D. Fredh, R. Fyfe, N. Jasiunas, P. Kołaczek, K. Kouli, R. Kozáková, M. Kupryjanowicz, P. Lagerås, M. Lamentowicz, M. Lindbladh, J. A. López-Sáez, R. Luelmo-Lautenschlaeger, K. Marcisz, F. Mazier, S. Mensing, A. M. Mercuri, K. Milecka, Y. Miras, A. M. Noryśkiewicz, E. Novenko, M. Obremska, S. Panajiotidis, M. L. Papadopoulou, A. Pędziszewska, S. Pérez-Díaz, G. Piovesan, A. Pluskowski, P. Pokorny, A. Poska, T. Reitalu, M. Rösch, L. Sadori, C. Sá Ferreira, D. Sebag, M. Słowiński, M. Stančikaitė, N. Stivrins, I. Tunno, S. Veski, A. Wacnik, and A. Masi. “Palaeoecological Data Indicates Land-Use Changes across Europe Linked to Spatial Heterogeneity in Mortality During the Black Death Pandemic.” Nature Ecology & Evolution 6, no. 3 (March 2022): 297-306.

“Large Citizen Science Projects” Use Data Mining to Explore Risk Factors for Canine Cancers

(p. 2) Every dog has its day, and July 14, 2004, belonged to a boxer named Tasha. On that date, the National Institutes of Health announced that the barrel-chested, generously jowled canine had become the first dog to have her complete genome sequenced. “And everything has kind of exploded since then,” said Elaine Ostrander, a canine genomics expert at the National Human Genome Research Institute, who was part of the research team.

. . .

In the 2000s, scientists identified the genetic underpinnings of a variety of canine traits, including curly coats and bobbed tails. They pinpointed mutations that could explain why white boxers were prone to deafness. And they found that corgis, basset hounds and dachshunds owed their stubby legs to a genetic aberration in a family of genes that also regulates bone development in humans.

These early studies “highlighted both the potential that we could learn from dogs, but also that we were going to need bigger sample sizes to do it really well,” said Elinor Karlsson, a geneticist at UMass Chan Medical School and the Broad Institute. And so, researchers began creating large citizen science projects, seeking DNA samples and data from dogs across the United States.

Pet owners rose to the challenge. The Golden Retriever Lifetime Study, which began recruiting in 2012, has been following more than 3,000 dogs in an effort to identify genetic and environmental risk factors for cancer, which is especially common in the breed. Since 2019, the Dog Aging Project, a long-term study of health and longevity, has enrolled nearly 50,000 dogs.

Dr. Karlsson’s own project, Darwin’s Dogs, is at 44,000 canines and counting. (Some 4,000 have had their genomes sequenced.) Researchers are mining the data for clues about bone cancer, compulsive behavior and other traits.

For the full story see:

Emily Anthes. “Scientists’ New Best Friends.” The New York Times, Pets Special Section (Sunday, June 30, 2024): 2.

(Note: ellipsis added.)

(Note: the online version of the story has the same date as the print version, and has the title “How Science Went to the Dogs (and Cats).”)

Mountains Are Not Sublime if You Need a Plain to Survive

(p. 13) Most of the people who have lived on this planet since the invention of agriculture have been peasants.

. . .

The cultivators, it is often assumed, are dreadfully uncultivated. And this alleged lack of sophistication has made them fair game for every kind of depredation. The food they produce has been expropriated by their overlords, by marauding armies and by totalitarian states. They have been conscripted as cannon fodder; entangled in debt and dependency as sharecroppers and serfs; starved, sometimes deliberately, in famines and prisons; forcibly converted to their masters’ religions; herded onto collective farms and slaughtered mercilessly when they revolt.

. . .

. . . very few of the countless millions who have eked a living from the land left enduring accounts of their own lives.

“This,” Joyce wrote, “is a world of a very ancient form of silence, peasant silence, something enmeshed in cultures that are largely oral in nature.”

. . .

“The wild as our sublime,” he writes, “makes no sense to the peasant.” (Joyce cites a Polish peasant interviewed in the 1960s who said, “I like it where the plain is; when I was in America I saw a mountain, and this was an awful view.”)

. . .

Joyce shows how the supreme value of the peasant is generational survival: The great task is to hand on to the child the land the peasant has inherited, making one’s own existence a kind of interlude between past and future.

For the full review, see:

Fintan O’Toole. “Fanfare for the Common Man.” The New York Times Book Review (Sunday, March 10, 2024): 13.

(Note: ellipses added.)

(Note: the online version of the review was updated Feb. 28, 2024, and has the title “A Love Song to His Roots.”)

The book under review above is:

Joyce, Patrick. Remembering Peasants: A Personal History of a Vanished World. New York: Scribner, 2024.

Chernow Channels McCloskey’s Index Card Advice

In her wonderful paper on how to research well and write clearly, Deirdre McCloskey suggests that we always carry with us a pack of 4 by 6 cards, so that we have them handy when we are hit by an epiphany or hear a relevant quote. (The suggestion probably also appears in the later book versions of her wonderful paper, but I do not have a copy handy to check.)

(p. C11) Mr. Chernow usually spends about twice as much time researching a book as writing it. He types up his research on a computer, so that he has it backed up, and then prints out the individual entries on paper with perforated edges that he can tear into 4-by-6-inch cards. (He was inspired to use index cards by Vladimir Nabokov, who wrote his novels on them.) He then files the cards chronologically and indexes them. His research on Grant fills some 25,000 cards packed into 22 boxes, all stacked up in the office of his Brooklyn brownstone under a big abstract painting.

For the full interview, see:

Alexandra Wolfe. “WEEKEND CONFIDENTIAL; Ron Chernow.” The Wall Street Journal (Saturday, Sept. 16, 2017 [sic]): C11.

(Note: the online version of the interview has the date Sept. 15, 2017 [sic], and has the title “WEEKEND CONFIDENTIAL; Ron Chernow’s New Chapter: Ulysses S. Grant.”)

The main Chernow book discussed in the interview is:

Chernow, Ron. Grant. New York: The Penguin Press, 2017.

McCloskey’s wonderful paper, mentioned above, is:

McCloskey, Deirdre. “Economical Writing.” Economic Inquiry 23, no. 2 (April 1985): 187-222.