Early Medical “Leaps of Ingenuity”

(p. A17) Using a panoply of colorful examples, the author artfully illustrates the frustrations, uncertainty, poorly founded confidence and frequent futility of medical practice in the prescientific age. Employing a consistently light and humorous touch, he effortlessly navigates a cornucopia of fascinating, esoteric and obscure patient histories.
The carefully selected vignettes demonstrate the befuddled mindset of the well-intentioned physicians who were forced to contend with the vagaries of damaged and failing human flesh without the benefit of anesthesia, and armed with little more than the fanciful theories of Galen (a second-century Greek who attributed disease to imbalances of the four “humors”: blood, phlegm, and yellow and black bile) and an elementary knowledge of human anatomy.
Yet despite their lack of mechanistic understanding, these individuals showed leaps of ingenuity no less startling than those of today’s physicians and genome rewriters. To avoid subjecting himself to the dangers of 18th-century surgery to remove a bladder stone, Mr. Morris tells us, the French-born surgeon Claude Martin fashioned an instrument out of a knitting needle and a whalebone handle, which he then inserted through his urethra and used to manually file away the stone.

For the full review, see:
Adrian Woolfson. “BOOKSHELF; Desperate Remedies; Treatments of old for common health ills included tobacco-smoke enemas, arsenic cigarettes–and the “Pigeon’s-Rump Cure.” The Wall Street Journal (Tuesday, Dec. 13, 2018): A17.
(Note: ellipses added.)
(Note: the online version of the review has the date Dec. 12, 2018, and has the title “BOOKSHELF; ‘The Mystery of the Exploding Teeth’ Review: Desperate Remedies; Treatments of old for common health ills included tobacco-smoke enemas, arsenic cigarettes–and the “Pigeon’s-Rump Cure.”)

The book under review, is:
Morris, Thomas. The Mystery of the Exploding Teeth: And Other Curiosities from the History of Medicine. New York: Dutton, 2018.

A Tale of Two Bookstores: New York City Subsidizes Amazon and Regulates the Strand

(p. A22) Since it opened in 1927, the Strand bookstore has managed to survive by beating back the many challenges — soaring rents, book superstores, Amazon, e-books — that have doomed scores of independent bookshops in Manhattan.
With its “18 Miles of Books” slogan, film appearances and celebrity customers, the bibliophile’s haven has become a cultural landmark.
Now New York City wants to make it official by declaring the Strand’s building, at the corner of Broadway and 12th Street in Greenwich Village, a city landmark.
There’s only one problem: The Strand does not want the designation.
Nancy Bass Wyden, who owns the Strand and its building at 826 Broadway, said landmarking could deal a death blow to the business her family has owned for 91 years, one of the largest book stores in the world.
So at a public hearing on Tuesday before the city’s Landmarks Preservation Commission, her plea will be simple, she said: “Do not destroy the Strand.”
Like many building owners in New York, Ms. Wyden argues that the increased restrictions and regulations required of landmarked buildings can be cumbersome and drive up renovation and maintenance costs.
“By landmarking the Strand, you can also destroy a piece of New York history,” she said. “We’re operating on very thin margins here, and this would just cost us a lot more, with this landmarking, and be a lot more hassle.”
. . .
Another rich twist, Ms. Wyden said, was that the move coincides with the announcement that Amazon — not exactly beloved by brick-and-mortar booksellers — plans to open a headquarters in Queens, after city and state leaders offered upwards of $2 billion in incentives to Amazon and its multibillionaire chief executive, Jeff Bezos.
“The richest man in America, who’s a direct competitor, has just been handed $3 billion in subsidies. I’m not asking for money or a tax rebate,” Ms. Wyden said. “Just leave me alone.”
. . .
Owners of buildings with landmark status are in many cases barred from using plans, materials and even paint colors that vary from the original design without the commission’s approval.
. . .
Ms. Wyden — who is married to Senator Ron Wyden of Oregon, whom she met at the similarly renowned Powell’s book store in Portland — is a third-generation owner of the Strand, which stocks roughly 2.5 million used, rare and new books and employs 230 people.
. . .
While she would not divulge the bookstore’s finances, she said that she could make more money renting out the Strand’s five floors, but she loves the family business too much.
She accused city officials of trying to hurry the landmarking process, leaving her little time to prepare a defense, especially during the holiday rush.
“It’s our busiest time of year, and we should be focused on customers and Christmas, which is where we make our most money,” Ms. Wyden said. “But they have no sympathy for that.”

For the full story, see:
Corey Kilgannon. “‘Declaring Strand Bookstore a Landmark Would Kill It, Says Strand.” The New York Times (Tuesday, Dec. 4, 2018): A22.
(Note: ellipses added.)
(Note: the online version of the story has the date Dec. 3, 2018, and has the title “Declare the Strand Bookstore a City Landmark? No Thanks, the Strand Says.” The online version says that the New York print edition appeared on p. A20 and had the title: “A Bid to Preserve Strand Bookstore Would Destroy It, Owner Says.” The page and title in the citation I give further above, is from the National print edition that I receive.)

George Bittlingmayer Offers Advance Praise for Openness to Creative Destruction

For tens of thousands of years, before the Age of Innovation, human beings merely survived by hunting, gathering or tilling, and lived in caves or dirty, squalid huts. In marked contrast, the average person alive today enjoys a standard of living and access to entertainment, medical services, travel, and communications technology that our ancestors would have regarded as miraculous. Art Diamond skillfully shows how we got the many wonders we take for granted – everything from indoor plumbing to SUVs to iPhones – by telling the stories of the determined tinkerers, iconoclasts and visionaries who wouldn’t take “no” for an answer. They succeeded because they were willing to wage the good fight and because they could draw on flawed but ultimately supportive legal, cultural and economic institutions. Diamond also addresses the question of whether the Age of Innovation has run its course, and he provides a timely warning about the dangers that current political and intellectual forces pose to the many potential innovations yet to come. The Age Innovation may end, but whether it does is largely in our hands.

George Bittlingmayer, Economist, Angel Investor, and Professor Emeritus, University of Kansas.

Bittlingmayer’s advance praise is for:
Diamond, Arthur M., Jr. Openness to Creative Destruction: Sustaining Innovative Dynamism. New York: Oxford University Press, forthcoming June 2019.

“Profit Feeds Impact at Scale”

(p. 1) Eric Reynolds will tell you that he is on the verge of freeing much of humanity from the deadly scourge of the cooking fire. He can halt the toxic smoke wafting through African homes, protect what is left of the continent’s forest cover and help rescue the planet from the wrath of climate change.
He is happy to explain, at considerable length, how he will systematically achieve all this while constructing a business that can amass billions in profit from an unlikely group of customers: the poorest people on earth.
He will confess that some people doubt his hold on reality.
“A lot of people think it’s too good to be true,” says Mr. Reynolds, a California-born entrepreneur living in Rwanda. “Most people think I am pretty out there.”
The company he is building across Rwanda, Inyenyeri, aims to replace Africa’s overwhelming dependence on charcoal and firewood with clean-burning stoves powered by wood pellets. The business has just a tad more than 5,000 customers and needs perhaps 100,000 to break even. Even its chief operating officer, Claude Mansell, a veteran of the global consulting company Capgemini, wonders how the story will end.
“Do we know that it’s going to work?” he asks. “I don’t know. It’s never been done before.”
Inyenyeri presents a real-world test of an idea gaining traction among those focused on economic development — that profit-making businesses may be best positioned to deliver critically needed services to the world’s poorest communities.
Governments in impoverished countries lack the finance to attack threats to public health, and many are riddled with corruption (though, by reputation, not Rwanda’s). Philanthropists and international aid organizations play key roles in areas such as immunizing children. But turning plans for basic services into mass-market realities may require the potent incentives of capitalism. It is a notion that has provoked the creation of many businesses, most of them failures.
“Profit feeds impact at scale,” says Mr. Reynolds, now in the midst of a global tour (p. 8) as he courts investment on top of the roughly $12 million he has already raised. “Unless somebody gets rich, it can’t grow.”
More than four decades have passed since Mr. Reynolds embarked on what he portrays as an accidental life as an entrepreneur, an outgrowth of his fascination with mountaineering. He dropped out of college to start Marmot, the outdoor gear company named for the burrowing rodent. There, he profited by protecting Volvo-driving, chardonnay-sipping weekend warriors against the menacing elements of Aspen. Now, he is trying to build a business centered on customers for whom turning on a light switch is a radical act of upward mobility.
. . .
To succeed, a stove had to be so convenient and clean burning that women preferred it over their existing cooking method.
Mr. Reynolds began testing stoves made in Italy, India, the United States and China. He tried making his own.
He came to realize that the magic was in the combination of stove and fuel. He experimented with making charcoal out of corncobs. (“A stupid idea,” he says.) He tried burning banana leaves. Then he discovered wood pellets, which involve compressing wood and eliminating water, the element that produces much of the smoke.
He settled on a Dutch-made stove that reduces wood down to clean-burning gases. Using pellets reduced the need for wood by 90 percent compared with charcoal. But those stoves cost more than $75.
Then came the epiphany: Inyenyeri could supply the stoves for free while collecting revenue from subscriptions for pellets. Rwanda was urbanizing rapidly, and city dwellers rely on charcoal. They would be eager to switch to pellets, which were 30 to 50 percent cheaper.
. . .
(p. 9) The business model would get more attractive as the cost of charcoal climbed, and as innovation inevitably made stoves more efficient. Inyenyeri would also stand to collect revenue from an arrangement it later entered into with the World Bank to sell credits for reducing emissions.
In 2010, Mr. Reynolds sold his house in Boulder and went all in on Inyenyeri. He unloaded his wine cellar, liquidated his retirement accounts and moved to Rwanda with no plan to leave.
. . .
“This business model will happen,” he says. “If it’s not Inyenyeri that’s the first mover, then it will be someone else who learns from our mistakes and does it better. It’s too big of an opportunity.”

For the full story, see:
Peter S. Goodman. “‘A Low-Cost Fix for Africa’s Silent Killer.” The New York Times, SundayBusiness Section (Sunday, Dec. 6, 2018): 1 & 8-9.
(Note: ellipses added.)
(Note: the online version of the story has the date Dec. 5, 2018, and has the title “Toxic Smoke Is Africa’s Quiet Killer. An Entrepreneur Says His Fix Can Make a Fortune.”)

Global Warming Allows “Visionary Entrepreneurs” to Grow More “Superb” Sparkling Wine

(p. D4) . . . England, now in its third decade as a sparkling wine producer, is demonstrating that its bubbly output can be superb.
. . .
The early pioneers of English sparkling wine were bold, though idiosyncratic in the way of visionary entrepreneurs.
. . .
The growth in English sparkling wine is apparent all over the south of England. From Kent in the east through East and West Sussex, Hampshire, Dorset and as far west as Cornwall, new vineyards for sparkling wine are being planted at a dizzying rate. Winemakers who once imagined they were bound for France or Australia are instead staying home in England to make sparkling wine.
. . .
Nobody would mistake an English vineyard for one in Champagne. Walking through Gusbourne’s Boot Hill Vineyard with the winemaker Charlie Holland on a blustery, misty fall day, I noted that the rows of vines were far wider than one would find in Champagne, and the vines trained higher on their trellises.
In order to achieve ripeness in the colder English climate, the vines need to be planted less densely than in France, Mr. Holland said, to minimize the competition. And the vines need to have a denser canopy of leaves to promote photosynthesis, so the rows have to be wider apart so the leaves in one row won’t shade the fruit in another.
“It’s not the same parameters as in Champagne, and not the same ripeness levels,” Mr. Holland said.
Indeed, the Champagne region was once considered a marginal climate, on the blurry edge of the line at which grapes could reliably ripen. Thirty years ago, it was a struggle. Now, with climate change, the issue is whether Champagne is getting too warm.
The edge has now moved up to the south of England, where everybody agrees that the 2018 vintage was the biggest and best ever for sparkling wine.
“It was a fantastic, happy year for English wine,” said Tamara Roberts, chief executive of Ridgeview Estate in Sussex, a family operation that planted its first vines in the South Downs in 1995. It was so good that many estates spent the harvest scrambling for vats and tanks to hold the unexpected volume of wine.

For the full commentary, see:
Eric Asimov. “THE POUR; Great Bubbly From England, Believe It or Not.” The New York Times (Wednesday, Dec. 26, 2018): D4.
(Note: ellipses added.)
(Note: the online version of the commentary has the date Dec. 20, 2018.”)

Richest Man in World in 1836 Died of an Infection that Modern Antibiotics Cure

(p. A2) Rising incomes alone cannot capture how much better life has gotten. “Nathan Rothschild was surely the richest man in the world when he died in 1836,” economists Max Roser and Esteban Ortiz-Ospina wrote in 2017. “But the cause of his death was an infection–a condition that can now be treated with antibiotics sold for less than a couple of cents. Today, only the very poorest people in the world would die in the way that the richest man of the 19th century died.”
Mr. Roser is the founder of Our World in Data, a website that tracks the evolution of human welfare over the last few centuries. Scroll through the charts, articles and data sets, and you will be stunned by how much better life has become in just the last few decades: Child mortality, illiteracy and deaths from violence have all plummeted, and life expectancy has gone up.

For the full commentary, see:
Greg Ip. “Stop Calling It ‘Vocational Training’; How we speak about education reflects class prejudice.” The Wall Street Journal (Wednesday, January 3, 2019): A2.
(Note: the online version of the commentary has the date Jan. 2, 2019, and has the title “CAPITAL ACCOUNT; The World Is Getting Quietly, Relentlessly Better.”)

The Roser and Oritz-Ospina piece mentioned above, is:
Max Roser and Esteban Ortiz-Ospina (2018) – “Global Extreme Poverty”. Published online at OurWorldInData.org. Retrieved from: ‘https://ourworldindata.org/extreme-poverty’ [Online Resource]

Michael Barrier Offers Advance Praise for Openness to Creative Destruction

Walt Disney has been written about as an artist and an entrepreneur. The central virtue of Art Diamond’s book is that he not only writes about Disney in both roles, but he also explains how Disney’s success in each role strengthened his success in the other.

Michael Barrier, animation historian. Author of The Animated Man: A Life of Walt Disney, and other works

Barrier’s advance praise is for:
Diamond, Arthur M., Jr. Openness to Creative Destruction: Sustaining Innovative Dynamism. New York: Oxford University Press, forthcoming June 2019.

Do Not Invest in Startups That Sell Dollar Bills for 90 Cents

(p. B12) There is a joke in Silicon Valley that startups can have a booming business if they sell dollar bills for 90 cents–that is, until they run out of dollar bills. A bike-sharing crash in China shows the folly of taking such startups too seriously now that venture capital is drying up.

For the full commentary, see:
Jacky Wong. “Startups in China Face a Cash Crunch.” The Wall Street Journal (Wednesday, Dec. 27, 2018): B12.
(Note: the online version of the commentary has the date Dec. 27, 2018, and has the title “Time Is Running Out for Unprofitable Chinese Startups.” The second sentence quoted above, follows the wording of the online, rather than the slightly different print version.)

“The Death of the Dead-End Secretary”

(p. A25) Evelyn Berezin, a computer pioneer who emancipated many a frazzled secretary from the shackles of the typewriter nearly a half-century ago by building and marketing the first computerized word processor, died on Saturday [December 8, 2018] in Manhattan. She was 93.
. . .
In an age when computers were in their infancy and few women were involved in their development, Ms. Berezin (pronounced BEAR-a-zen) not only designed the first true word processor; in 1969, she was also a founder and the president of the Redactron Corporation, a tech start-up on Long Island that was the first company exclusively engaged in manufacturing and selling the revolutionary machines.
To secretaries, who constituted 6 percent of the American work force then, Redactron word processors arrived in an office like a trunk of magic tricks, liberating users from the tyranny of having to retype pages marred by bad keystrokes and the monotony of copying pages for wider distribution. The machines were bulky, slow and noisy, but they could edit, delete, and cut and paste text.
Modern word processors, which appear as programs on computers, long ago simplified the tasks of authors, journalists and other writers — sometimes after misgivings over the risk of surrendering to a future of dystopian technology — but became so efficient in offices that they killed off the need for most of the old-fashioned secretarial skills Ms. Berezin was trying to enhance.
“I’m embarrassed to tell you that I never thought of it — it never entered my mind” that the word processor might endanger women’s jobs, Ms. Berezin said in an interview for this obituary in 2017. Though she was not an ardent feminist, she said, her first ad for the Redactron word processor was placed in Ms. magazine in 1971, hailing “the death of the dead-end secretary.”
. . .
Even in her Redactron heyday, Ms. Berezin was hardly alone in the word processing business. Her chief competitor, International Business Machines, made devices that relied on electronic relays and tapes, not semiconductor chips. I.B.M. soon caught up technologically and swamped the market in the 1970s and ′80s, pursued by a herd of brands like Osborne, Wang, Tandy and Kaypro.
But for a few years after Redactron started shipping its computerized word processors in September 1971, Ms. Berezin was a lioness of the young tech industry, featured in magazine and news articles as an adventurous do-it-herself polymath with the logical mind of an engineer, the curiosity of an inventor and the entrepreneurial skills of a C.E.O.
In a 1972 profile in The New York Times, the business writer Leonard Sloane wrote: “Miss Berezin, a serious, soft-spoken individual, nevertheless talks at times like a systems engineer (which she is), a sales executive (which she is) and a proponent of a sophisticated product (which she is). She is also obviously a woman on the senior level of a field where her sex are still a rarity at any level.”
Early in her career, Ms. Berezin designed numerous single-purpose computer systems. They calculated the firing ranges of big guns, controlled the distribution of magazines, kept accounts for corporations and automated banking transactions. She also claimed credit for the world’s first computerized airline reservations system.
“Why is this woman not famous?” the British writer and entrepreneur Gwyn Headley asked in a 2010 blog post.
“Without Ms. Berezin,” he added enthusiastically, “there would be no Bill Gates, no Steve Jobs, no internet, no word processors, no spreadsheets; nothing that remotely connects business with the 21st century.”
Credit for her early achievements does appear to have faded with time, perhaps under the obliterating speed of technological change, the greater notice paid to her corporate competitors, and the tendency of the tech world to diminish the accomplishments of women.

For the full obituary, see:
Robert D. McFadden. “Evelyn Berezin, Computer Pioneer Who Built First Word Processor, Dies at 93.” The New York Times (Tuesday, Dec. 11, 2018): A25.
(Note: ellipses, and bracketed date, added.)
(Note: the online version of the obituary has the date Dec. 10, 2018, an has the title “Evelyn Berezin, 93, Dies; Built the First True Word Processor.”)

The book mentioned as a source above, is:
Kirschenbaum, Matthew G. Track Changes: A Literary History of Word Processing. Cambridge, MA: Belknap Press, 2016.

Distorted Incentives Can Lead to Short-Termism or to Long-Termism

(p. B1) Capitalism is often accused of fostering short-termism, making companies chase quarterly profit numbers to satisfy shareholders.
A better criticism is that the targets corporate executives aim for are grossly simplified, thanks to the twisting line of responsibility from corner office to fund manager to pension fund and ultimately to the savers who own the company.
These distorted incentives sometimes lead to short-termism; at other times, shareholder enthusiasm pushes executives to focus far too much on the long run, as in the wild mining boom that turned to bust in 2011, or the dot-com bubble.

For the full commentary, see:
James Mackintosh. “STREETWISE; Fixing Capitalism, One Disclosure at a Time.” The Wall Street Journal (Wednesday, Nov. 28, 2018): B1 & B12.
(Note: the online version of the commentary has the date Nov. 27, 2018.)

James Dyson Pursued a Slow Hunch by Trial and Error

(p. 6) Mr. Dyson discovered his passion for design at an early age, and eventually began work on his signature product, the bagless vacuum cleaner. It took several years, but he brought the product to market, founding Dyson Ltd. in 1991. Soon, Dyson was expanding internationally and developing new products, including washing machines, fans, heaters, air purifiers, hand dryers and hair dryers. It is now at work on an electric car.
. . .
And what was so different about your vacuums?
I saw the problem, and I saw a possible solution, which was the huge cyclones outside cement plants and timber yards that collect dust all day long. So I started building various versions of that technology. As it happens, it didn’t work. I had to spend four or five years coming up with different types of cyclonic separation devices in order to make it work.
It took a lot of empirical work. I had to build the prototypes, one or two a day, which sounds tedious, but actually it was fascinating. I’m still doing it today. It always is a wonderful adventure of excitement and disappointment. Almost everything you do is a failure, until you get the one success that works..
How did you pay for all that research and development before you had a product to sell?
I was borrowing it all from the bank. Going deeper and deeper into debt. By the time I launched the vacuum cleaner, I was two million pounds in debt. I think the bank got in a bit deeper than they intended to, but I had an interesting bank manager. I asked him why he lent me the money, and he said, “I went home to my wife and said, ‘What do you think about vacuum bags and vacuum cleaners?’ And she said, ‘Dreadful, dreadful.'”
. . .
Why are you in favor of Brexit?
I think we should be independent. Europe has become more and more of a unified society where all the laws are made in Brussels. I don’t believe it’s ever been right for Britain.
Britain has always been a globally facing country, with our empire, if I dare mention that, covering half the globe. We have a pioneering and global outlook. There’s no room for us in Europe.
What about the prospect of economic disruption to England
All cars coming into England from America have a 10 percent duty on them, and most of that goes to Brussels. Europe is a protectionist setup designed to keep competitors out. It’s not a good thing to be in. We believe in free trade. And if any bankers are leaving London, it’s got nothing to do with Brexit. It was the right decision for Britain.

For the full interview, see:
David Gelles, interviewer. “‘Follow the Design, Not the Market.” The New York Times, SundayBusiness Section (Sunday, Dec. 6, 2018): 6.
(Note: ellipses added; bold in original.)
(Note: the online version of the interview has the date Dec. 5, 2018, and has the title “CORNER OFFICE; James Dyson: ‘The Public Wants to Buy Strange Things’.” The first quoted paragraph, and the bold questions, are by David Gelles. The answers are by James Dyson.)