During Pandemic, Delayed Medical Procedures Rose from 4.6 to 6 Million in England’s Socialized Healthcare System

(p. A8) LONDON — Lara Wahab had been waiting for more than two years for a kidney and pancreas transplant, but months had passed without any word. So last month she called the hospital, and got crushing news.

There had been a good match for her in October [2021], the transplant coordinator told her, which the hospital normally would have accepted. But with Covid-19 patients filling beds, the transplant team could not find her a place in the intensive care unit for postoperative care. They had to decline the organs.

“I was just in shock. I knew that the N.H.S. was under a lot of strain, but you don’t really know until you’re waiting for something like that,” she said, referring to the National Health Service. “It was there, but it sort of slipped through my fingers,” she added of the transplant opportunity.

Ms. Wahab, 34, from North London, is part of an enormous and growing backlog of patients in Britain’s free health service who have seen planned care delayed or diverted, in part because of the pandemic — a largely unseen crisis within a crisis. The problems are likely to have profound consequences that will be felt for years.

The numbers are stark: In England, nearly 6 million procedures are currently delayed, a rise from the backlog of 4.6 million before the pandemic, according to the N.H.S. The current delays most likely impact more than five million people — a single patient can have multiple cases pending for different ailments — which represents almost one-tenth of the population. Hundreds of thousands more haven’t been referred yet for treatment, and many ailments have simply gone undiagnosed.

For the full story, see:

Megan Specia. “In Britain, an Ever-Growing Backlog of Non-Covid Care.” The New York Times (Thursday, January 27, 2022): A8.

(Note: bracketed year added.)

(Note: the online version of the story was updated January 27, 2022, and has the title “‘I Feel Really Hopeless’: In U.K., Millions See Non-Covid Health Care Delayed.”)

Middle Class Hurt by California Mandate for New Home Batteries and Solar Panels

(p. B1) This month, state regulators updated California’s building code to require some new homes and commercial buildings to have solar panels and batteries and the wiring needed to switch from heaters that burn natural gas to heat pumps that run on electricity. Energy experts say it is one of the most sweeping single environmental updates to building codes ever attempted by a government agency.

But some energy and building experts warn that California may be taking on too much, too quickly and focusing on the wrong target — new buildings, rather than the much larger universe of existing structures. Their biggest fear is that these new requirements will drive up the state’s already high construction costs, putting new homes out of reach of middle- and lower-income families that cannot as easily afford the higher upfront costs of cleaner energy and heating equipment, which typically pays for itself over years through (p. B3) savings on monthly utility bills.

. . .

Adding solar panels and a battery to a new home can raise its cost by $20,000 or more. While that might not matter to somebody buying a million-dollar property, it could be a burden on a family borrowing a few hundred thousand dollars to buy a home.

“You’re going to see the impact in office rents. You’re going to see it in the cost of the milk in your grocery store,” said Donald J. Ruthroff, a principal at Dahlin Group Architecture Planning in Pleasanton, Calif. “There’s no question this is going to impact prices across the board.”

. . .

The Sycamore Square townhouses were the last ones developed in San Bernardino before the solar mandate took effect last year. Glenn Elssmann, a partner in the project who hired Mr. Marini’s company as the contractor, said the added cost of the solar requirement would have made construction of the development impossible. Homes in Sycamore Square started at $340,000 for the four-bedroom, three-bath units and reached as high as $370,000.

Jimmie Joyce, 44, who works in payroll at the Los Angeles County Department of Public Health, will soon close on the purchase of a house in Sycamore Square after trying for almost a year to buy closer to Inglewood, a city near the Los Angeles International Airport where he lives now. His commute will likely increase from about 40 minutes to an hour and a half.

“I, for one, didn’t even plan on moving out that far,” Mr. Joyce said. “The way the market is, people are just overbidding to just try to get in things.” He said he made an offer $10,000 to $15,000 higher than the asking price on a home that ended up with more than 70 bids, including one that was $60,000 more than his.

His new home is already expensive for him, he said, and adding $10,000 to $20,000 more for solar, a battery and other amenities “would make that much more challenging.”

The changes regulators adopted this month will also require most new commercial buildings, including schools, hotels, hospitals, office buildings, retailers and grocery stores, and apartment buildings and condos above three stories to include solar and batteries. And regulators will require single-family homes to have wiring that will allow them to use electric heat pumps and water heaters, rather than ones that burn natural gas. About 55 percent of California’s homes use electric heat and 45 percent use natural gas.

For the full story, see:

Ivan Penn. “Greener Buildings, for a Lot of Green.” The New York Times (Monday, August 30, 2021): B1 & B3.

(Note: ellipses added.)

(Note: the online version of the story was updated Sept. 9, 2021, and has the title “California’s Plan to Make New Buildings Greener Will Also Raise Costs.”)

Democrat-Praised “Whistleblower” Rick Bright, Not Trump Admin, Delayed Molnupiravir by Months at Peak of Pandemic

(p. A17) When Merck and Ridgeback Biotherapeutics announced on Oct. 1 [2021]that their new antiviral pill reduced Covid hospitalizations by roughly half, some in the media blamed Donald Trump. An Axios headline: “Before Merck backed COVID antiviral, Trump admin turned it down.” In fact, Trump officials pushed for government funding to accelerate the development of the drug, molnupiravir. They were opposed by a career official, Rick Bright, whom Democrats praised as a “whistleblower.”

Mr. Bright joined the Biomedical Advanced Research and Development Authority in 2010 and became Barda’s director in 2016.

. . .

Emory had licensed molnupiravir to Ridgeback, which in April 2020 requested $100 million from the government to fast-track studies in humans. Mr. Bright says Trump officials ordered Barda officials “to fund the Ridgeback proposal as quickly as possible, and preferably within 24 hours.” But he said “Ridgeback had not followed the proper procedure for receiving BARDA funding.” Barda declined the request, and Ridgeback collaborated with Merck, which put its own capital at risk.

After Mr. Bright’s reassignment, Barda funding for trials, manufacturing and advance purchases of monoclonal antibodies proved critical in accelerating their development. Molnupiravir would likely have been available much sooner had Barda provided funding as Trump officials urged last spring.

For the full commentary, see:

Allysia Finley. “Who Slowed Merck’s Covid Remedy?” The Wall Street Journal (Monday, October 11, 2021): A17.

(Note: ellipsis, an bracketed year, added.)

(Note: the online version of the commentary has the date October 10, 2021, and has the same title as the print version.)

To Get “Free” Covid Pills from 60 Miles Away You Pay Private Uber to Deliver

(p. 1) Just after 1 p.m. on Tuesday last week, my phone buzzed with a text message from my mother: “Well, came down with cold, aches, cough etc over wknd.” She had taken an at-home coronavirus test. It was positive.

Having spent the past year writing about Covid-19 vaccines and treatments for The New York Times, I knew a lot about the options available to people like my mother. Yet I was about to go on a seven-hour odyssey that would show me there was a lot I didn’t grasp.

. . .

(p. 3) In the end, my scramble to find a prescriber turned out to be unnecessary. In the early evening, my mother got an unexpected call from a doctor with her primary care provider. She told the doctor about her symptoms and about the Rite Aid I had found with Paxlovid in stock.

The doctor told her that he was surprised that we had been able to track down Paxlovid. He phoned in a prescription to the Rite Aid.

Now we just needed to pick up the pills before the pharmacy closed in about an hour.

Uber came to the rescue. I requested a pickup at the Rite Aid and listed the destination as my mother’s home, some 60 miles away.

Once a driver accepted the ride, I called him and explained my unusual request: He’d need to get the prescription at the pharmacy window and then drive it to my mother’s. I told him I’d give him a 100 percent tip.

The driver, who asked me not to use his name in this article, was game. He delivered the precious cargo just after 8 p.m. My mother swallowed the first three pills — the beginning of a five-day, 30-pill regimen — within minutes of the driver’s arrival.

. . .

. . . the fact that the process was so hard for a journalist whose job it is to understand how Paxlovid gets delivered is not encouraging. I worry that many patients or their family would give up when told “no” as many times as I was.

I was also reminded that even a “free” treatment can come with significant costs.

The federal government has bought enough Paxlovid for 20 million Americans, at a cost of about $530 per person, to be distributed free of charge. But I spent $256.54 getting the pills for my mother. I paid $39 for the telemedicine visit with the provider who told my mother that she would need to visit in person. The rest was the Uber fare and tip. Many patients and their families can’t afford that.

President Biden recently called the Pfizer pills a “game changer.” My experience suggests it won’t be quite so simple.

For the full story, see:

Rebecca Robbins. “A 7-Hour Odyssey to Get My Mom Covid Pills.” The New York Times, SundayBusiness Section (Sunday, January 23, 2022): 1 & 3.

(Note: ellipses added.)

(Note: the online version of the story has the date Jan. 19, 2022, and has the title “When My Mom Got Covid, I Went Searching for Pfizer’s Pills.”)

Change in Census Question-Wording Drove Seeming Decline in “White” Population

(p. A17) The most common reaction to the release of the 2020 census was summed up in the headline “Census Data show the number of white people fell.” The data show the number of whites declining by 8.6%. This observation was often coupled with a political projection: that while gerrymandering could benefit Republicans in 2022, the political future belongs to the Democratic Party, which commands large majorities among minorities.

. . .

In the 2010 census, 53% of those who said they were of Hispanic origin checked off only “white,” a 58% increase in numbers from 2000. That rise in white Hispanics helped account for the increase in the number of whites from the prior census. But in the 2020 census, a mere 20.3% of Hispanics checked off only “white,” contributing to the 8.6% decline in the total number of people identifying only as white.

That dramatic change probably stemmed not from a shift in social consciousness or demographics, but from a subtle change in the 2020 question about race. In 2010 the census asked respondents to check off whether they were white, black or African-American, American Indian or Alaska Native, various varieties of Asian or Pacific Islander, and “some other race.” They may check off as many race boxes as are applicable.

But in 2020 the census asked respondents who checked off “white” to specify their nationality: “Print, for example, German, Irish, Italian, Lebanese, Egyptian, etc.” No Spanish-speaking nationality was listed. That likely created the impression that Hispanic was another race, notwithstanding the previous question’s disclaimer that “Hispanic origins are not races.”

For the full commentary, see:

John B. Judis. “How the Census Misleads on Race.” The Wall Street Journal (Monday, August 30, 2021): A17.

(Note: ellipsis added.)

(Note: the online version of the commentary has the date August 29, 2021, and has the same title as the print version.)

Democratic Gerrymandering in New York Greater Than Republican Gerrymandering in Any Other State

(p. A1) Democrats across the nation have spent years railing against partisan gerrymandering, particularly in Republican states — most recently trying to pass federal voting rights legislation in Washington to all but outlaw the practice.

But given the same opportunity for the first time in decades, Democratic lawmakers in New York adopted on Wednesday [February 3, 2022] an aggressive reconfiguration of the state’s congressional districts that positions the party to flip three seats in the House this year, a greater shift than projected in any other state.

. . .

(p. A21) Overall, the new map was expected to favor Democratic candidates in 22 of New York’s 26 congressional districts. Democrats currently control 19 seats in the state, compared with eight held by Republicans. New York is slated to lose one seat overall this year because of national population changes in the 2020 census.

“It’s a master class in how to draw an effective gerrymander,” said Michael Li, senior counsel for the Democracy Program at the Brennan Center for Justice, which has also sounded alarms about attempts by Republicans to gerrymander and pass other restrictive voting laws.

“Sometimes you do need fancy metrics to tell, but a map that gives Democrats 85 percent of the seats in a state that is not 85 percent Democratic — this is not a particularly hard case,” he said.

For the full story, see:

Nicholas Fandos, Luis Ferré-Sadurní and Grace Ashford. “Gerrymandering by New York Democrats May Flip 3 House Seats.” The New York Times (Thursday, February 3, 2022): A1 & A21.

(Note: ellipsis added.)

(Note: the online version of the story has the date February 2, 2022, and has the title “A ‘Master Class’ in Gerrymandering, This Time Led by N.Y. Democrats.”)

“People Are Now Coming to Their Own Conclusions About Covid”

(p. 3) Lauren Terry, 23, thought she would know what to do if she contracted Covid-19. After all, she manages a lab in Tucson that processes Covid tests.

But when she developed symptoms on Christmas Eve, she quickly realized she had no inside information.

“I first tried to take whatever rapid tests I could get my hands on,” Ms. Terry said. “I bought some over the counter. I got a free kit from my county library. A friend gave me a box. I think I tried five different brands.” When they all turned up negative, she took a P.C.R. test, but that too, was negative.

With clear symptoms, she didn’t believe the results. So she turned to Twitter. “I was searching for the Omicron rapid test efficacy and trying to figure out what brand works on this variant and what doesn’t and how long they take to produce results,” she said. (The Food and Drug Administration has said that rapid antigen tests may be less sensitive to the Omicron variant but has not identified any specific tests that outright fail to detect it.) “I started seeing people on Twitter say they were having symptoms and only testing positive days later. I decided not to see anybody for the holidays when I read that.”

She kept testing, and a few days after Christmas she received the result she had expected all along.

Though it’s been almost two years since the onset of the pandemic, this phase can feel more confusing than its start, in March 2020. Even P.C.R. tests, the gold standard, don’t always detect every case, especially early in the course of infection, and there is some doubt among scientists about whether rapid antigen tests perform as well with Omicron. And, the need for a 10-day isolation period was thrown into question after the Centers for Disease Control and Prevention announced that some people could leave their homes after only five days.

“The information is more confusing because the threat itself is more confusing,” said David Abramson, who directs the Center for Public Health Disaster Science at the N.Y.U. School of Global Public Health. “We used to know there was a hurricane coming at us from 50 miles away. Now we have this storm that is not well defined that could maybe create flood or some wind damage, but there are so many uncertainties, and we just aren’t sure.”

Many people are now coming to their own conclusions about Covid and how they should behave. After not contracting the virus after multiple exposures, they may conclude they can take more risks. Or if they have Covid they may choose to stay in isolation longer than the C.D.C. recommends.

And they aren’t necessarily embracing conspiracy theories. People are forming opinions after reading mainstream news articles and tweets from epidemiologists; they are looking at real-life experiences of people in their networks.

For the full story, see:

Alyson Krueger. “Covid Experts, the Self-Made Kind.” The New York Times, SundayStyles Section (Sunday, January 23, 2022): 3.

(Note: the online version of the story has the date January 21, 2022, and has the title “So You Think You’re a Covid Expert (but Are You?).”)

When Humans Control Animals, Their Wily Resilience Can Cause “Unforeseen Consequences”

(p. A15) For the past three years, a gray squirrel has set out to ruin my life, chewing leaves off my beloved exotic hibiscus and geraniums.

. . .

. . . , Mary Roach’s “Fuzz: When Nature Breaks the Law” makes me feel grateful that my nemesis is only a rodent, and that I live in Ohio, not Colorado or India. My refrigerator will not be emptied by a bear; I will not be throttled by a leopard while taking out the compost.

. . .

There’s something demonic at work in India’s leopards and macaques, but the dilemma finds its root in human behavior. For centuries, feeding monkeys has been considered a religious offering, but this ritual has fueled a certain conviction on the monkeys’ part that humans are in service to them. Ms. Roach’s attempts to pin down government officials on how they might tackle the problem (including hiring more monkey catchers and staffing more monkey sterilization centers) are hilariously convoluted and laced with bizarre anecdotes. She’s passed from one office to the next and back again, never getting an answer. Before redirecting her, one official “veered off into a story about a macaque that got inside the All India Institute of Medical Sciences and took to pulling IV needles out of patients’ arms and sucking the glucose like a child with a straw in a pop bottle.”

During World War II, the U.S. military established a naval air station on Midway Atoll, the strategically significant string of islets halfway between North America and Asia. But the islands turned out to be also a significant nesting ground for thousands of albatrosses, and the result was hundreds of collisions between the airplanes and the huge soaring birds. It is heartbreaking to read of sailors being made to club the long-living albatrosses—80,000 in one assault, 21,000 in another—to reduce the population. Still, nature prevailed. “For a brief time the hazard to aircraft was reduced,” read one report. “The following season there appeared to be as many albatrosses as before.” After every possible deterrent and lethal attack on the gentle birds failed, the air base was closed and in 1993 converted into a refuge. The contrast between this midcentury horror and the reverence shown earlier this year for Wisdom, the 70-year-old Laysan albatross still nesting on Midway, could hardly be more stark.

. . .

This book is largely about the unspooling of unforeseen consequences, and our feeble attempts to put the animal genies we’ve freed back into their bottles.

For the full review, see:

Julie Zickefoose. “BOOKSHELF; Rebellious Nature.” The Wall Street Journal (Tuesday, Nov. 2, 2021): A15.

(Note: ellipses added.)

(Note: the online version of the review has the date November 1, 2021, and has the title “BOOKSHELF; ‘Fuzz’ Review: Rebellious Nature.”)

The book under review is:

Roach, Mary. Fuzz: When Nature Breaks the Law. NY: W. W. Norton & Company, 2021.

Asteroids as Another Existential Threat

Do we best prepare for uncertain existential future threats by huge centrally planned government spending, or by allowing the flourishing of general purpose technologies and nimble entrepreneurs?

(p. C4) The most immediate threat isn’t from the largest or smallest asteroids but from those in between. Over the past two decades, asteroid hunters with NASA and other international space agencies have identified and tracked the orbits of more than 20,000 asteroids—also known as near-Earth objects—that pass through our neighborhood as they orbit the sun. Of those, about 2,000 are classified as potentially hazardous—asteroids that are large enough (greater than 150 yards in diameter) to cause local destruction and that come close enough to Earth to someday pose a threat.

The good news is that scientists don’t expect any of these known asteroids to collide with Earth within at least the next century. Some will come pretty close, though: On an unlucky Friday the 13th in April 2029, the thousand-foot-wide asteroid Apophis will pass a mere 19,000 miles from Earth—closer than the satellites that bring us DISH TV.

But here’s the bad news: Hundreds of thousands of other near-Earth asteroids, both large and small, haven’t been identified. We have no idea where they are and where they are going. On Feb. 15, 2013, a relatively small, 60-foot-wide asteroid traveling at 43,000 mph exploded in the atmosphere near the Russian city of Chelyabinsk, sending out a blast wave that injured 1,500 people. No one had seen the asteroid coming.

We need to find and track these unknown invaders as soon as possible. But while NASA’s “planetary defense” budget has been steadily increasing over the past decade, the $150 million allocated in 2019 for asteroid detection, asteroid tracking and related programs amounts to less than 1% of the space agency’s $21.5 billion budget.

For the full commentary, see:

Gordon L. Dillow. “The Asteroid Peril Isn’t Science Fiction.” The Wall Street Journal (Saturday, July 5, 2019): C4.

(Note: the online version of the commentary has the date July 5, 2019, and has the same title as the print version.)

Dillow’s commentary is related to his book:

Dillow, Gordon L. Fire in the Sky: Cosmic Collisions, Killer Asteroids, and the Race to Defend Earth. New York: Scribner, 2019.

Biden’s Cancer “Moonshot Is 100 Percent Hype”

(p. A17) WASHINGTON — President Biden unveiled a plan on Wednesday to reduce the death rate from cancer by at least 50 percent over the next 25 years — an ambitious new goal, he said, to “supercharge” the cancer “moonshot” program he initiated and presided over five years ago as vice president.

Mr. Biden, joined by his wife, Jill Biden, and Vice President Kamala Harris, also announced a campaign to urge Americans to undergo screenings that were missed during the coronavirus pandemic.

. . .

More screenings are not the answer — the only cancers for which screening has indisputably lowered the death rate are colon and cervical. Death rates for other cancers, like breast, have fallen, but a large part of the drop, if not all of it, is because of improved treatment, said Donald A. Berry, a biostatistician at the University of Texas M.D. Anderson Cancer Center who has spent decades studying these issues.

“Everybody loves early detection, but it comes with harms,” he said — principally, the harm of finding and treating tumors that do not need to be treated because they are innocuous. “The harms we know, but the benefits of screening are very uncertain,” he said.

If the age-adjusted cancer death rate were to plunge by 50 percent, it would have to be because cancers were being cured. Some treatments, like a drug that treats chronic myelogenous leukemia, have slashed death rates for that disease, but such marked effects in cancer are few and far between.

. . .

The White House billed the event as a fresh push by the president to “reignite” the moonshot program and “end cancer as we know it.”

. . .

Yet one Wall Street analyst who specializes in biotechnology and pharmaceuticals said that the time, money and effort might be better spent on initiatives to prevent cancer, like reducing smoking and rates of obesity. The Centers for Disease Control and Prevention says being obese increases a person’s risk of cancer. And reducing smoking is a proven way to cut the cancer death rate.

“This moonshot is 100 percent hype; this is the absolute wrong way to do this,” said the analyst, Stephen Brozak, the president of WBB Securities.

Presidents since Richard M. Nixon have sought to tackle cancer, of which there are more than 100 types of disease that can vary in how they grow, spread and respond to treatment. The cancer institute estimates that nearly 40 percent of men and women will be diagnosed with some type of cancer at some point during their lifetimes. The American Cancer Society estimates there will be 1.9 million new cases of cancer in the United States this year, and more than 609,000 cancer deaths.

For the full story, see:

Sheryl Gay Stolberg and Gina Kolata. “President Aims to Cut The Cancer Death Rate In Half Over 25 Years.” The New York Times (Thursday, February 3, 2022): A17.

(Note: ellipses added.)

(Note: the online version of the story has the date Feb. 2, 2022, and has the title “Biden Presents Ambitious Plan to Cut Cancer Death Rate in Half.”)

Expert Medical Advice Often Flip-Flops

(p. D6) A History of Medical Flip-Flops

Shifting medical advice is surprisingly common, and it tends to fall into three categories: emerging guidance, replacement advice and reversals.

Emerging guidance comes during times of crisis — like pandemics — and is destined to change quickly. In the past several months, guidance about the best way to treat Covid patients, masks to prevent transmission and the limits of vaccine protection have all shifted as knowledge of the coronavirus and its variants has evolved.

Sometimes it’s hard to tell the difference between replacement advice, which is issued when research improves on advice that came before it, and a full reversal, which comes about because a common medical practice got ahead of the science and never actually worked or even caused harm. Here are some examples of true medical flip-flops in recent years.

MENOPAUSE HORMONES TO PROTECT THE HEART: In 2002, decades of advice about the heart benefits of menopause hormones seemed to change overnight when a major study called the Women’s Health Initiative was halted after researchers detected more heart attacks in the women taking hormones. In hindsight, doctors had misinterpreted data from observational research. The current advice: Hormones can relieve menopause symptoms but shouldn’t be used for chronic disease prevention.

VIOXX AS A LOWER-RISK ARTHRITIS TREATMENT: In 1999, the Food and Drug Administration approved Vioxx as a breakthrough pain reliever because it lowered the risk of gastrointestinal problems. But by 2004, Merck had withdrawn the drug because studies showed it significantly raised the risk of heart attack.

ARTHROSCOPIC SURGERY ON AGING KNEES: For years, the partial removal of torn meniscus tissue was the most common orthopedic procedure in the United States, with about 700,000 performed a year. In 2013, a researcher in Finland compared the operation to a “sham” procedure and found there was no benefit. Most doctors now recommend physical therapy instead.

VITAMIN MEGADOSES TO LOWER CANCER AND HEART RISK: For years, doctors believed various vitamins could lower risk for cancer and heart disease, but a number of studies showed just the opposite. A study of beta carotene and vitamin A found that the supplements actually increased the risk of lung cancer in male smokers. A study of vitamin E and selenium, thought to protect against prostate cancer, increased risk for the disease.

STENTS FOR STABLE HEART DISEASE: Doctors used to insert stents — tiny wire mesh tubes that prop open arteries — in millions of otherwise stable patients with heart disease. A study found that the surgical procedure was no better than drug therapy for preventing heart attacks.

Dr. Vinay Prasad, associate professor at the University of California San Francisco, and Dr. Adam S. Cifu, a professor of medicine at the University of Chicago Department of Medicine, coined the term “medical reversal” and concluded that about 40 percent of common medical practices that they reviewed turned out to be useless or harmful. In their book, “Ending Medical Reversal: Improving Outcomes, Saving Lives,” they noted that most of these failed treatments were initially embraced because they were based on logical reasoning.

“The thing that’s often behind reversal: All of these things have a good story, they have good pathophysiological rationale,” Dr. Cifu said. “They should work. But things only work if they’ve been shown in people to work, and people are so complicated.”

For the full story, see:

Tara Parker-Pope. “Shifting Medical Advice Is a Feature, Not a Bug.” The New York Times (Tuesday, November 2, 2021): D6.

(Note: the online version of the story was updated Oct. 24, 2021, and has the title “Is the New Aspirin Advice a Medical Flip-Flop, or Just Science?” The paragraphs on menopause hormones to protect the heart and on vitamin megadoses to lower cancer and heart risk appear in the online version, but not in the print version.)

The book co-authored by Prasad and mentioned above is:

Prasad, Vinayak K., and Adam S. Cifu. Ending Medical Reversal: Improving Outcomes, Saving Lives. Baltimore: Johns Hopkins University Press, 2015.