The Health Hazards of Government Guidelines on Salt

SaltIntakeGuidelinesGraphic2014-08-17.jpgSource of graphic: online version of the WSJ article quoted and cited below.

(p. A1) A long-running debate over the merits of eating less salt escalated Wednesday when one of the most comprehensive studies yet suggested cutting back on sodium too much actually poses health hazards.

Current guidelines from U.S. government agencies, the World Health Organization, the American Heart Association and other groups set daily dietary sodium targets between 1,500 and 2,300 milligrams or lower, well below the average U.S. daily consumption of about 3,400 milligrams.
The new study, which tracked more than 100,000 people from 17 countries over an average of more than three years, found that those who consumed fewer than 3,000 milligrams of sodium a day had a 27% higher risk of death or a serious event such as a heart attack or stroke in that period than those whose intake was estimated at 3,000 to 6,000 milligrams. Risk of death or other major events increased with intake above 6,000 milligrams.
The findings, published in the (p. A2) New England Journal of Medicine, are the latest to challenge the benefit of aggressively low sodium targets–especially for generally healthy people. Last year, a report from the Institute of Medicine, which advises Congress on health issues, didn’t find evidence that cutting sodium intake below 2,300 milligrams reduced risk of cardiovascular disease.

For the story, see:
RON WINSLOW. “Low-Salt Diets May Pose Health Risks, Study Finds.” The Wall Street Journal (Thur., Aug. 14, 2014): A1-A2.
(Note: the online version of the story has the date Aug. 13, 2014, an has the title “Low-Salt Diets May Pose Health Risks, Study Finds.”)

Butter Is Back

(p. B1) Changing views of nutrition are turning butter into one of the great comeback stories in U.S. food history.
. . .
The revival flows in part from new legions of home gourmets inspired by celebrity chefs and cooking shows with butter-rich recipes. Butter makers have encouraged the trend, using food channels and websites to promote what they say is their products’ natural simplicity.
Butter’s shifting fortunes also reflect the vicissitudes of thinking on healthy eating that rattle the national diet. Families for decades opted for vegetable spreads because of concerns about butter’s high concentration of saturated fat, only to be told more recently that the trans fats traditionally contained in margarine are just as unhealthy. Many Americans also have altered their thinking on how important reducing all fat is for controlling weight.

For the full story, see:
KELSEY GEE. “Butter Makes Comeback as Margarine Loses Favor.” The Wall Street Journal (Thurs., June 26, 2014): B1-B2.
(Note: ellipsis added.)
(Note: the last quoted sentence was in the online, but not the print, version.)
(Note: the online version of the review has the date June 25, 2014, and has the title “Butter Makes Comeback as Margarine Loses Favor.”)

“The Lone Commando Who Answers to No One and Breaks Rules to Save Patients Is No Longer a Viable Job Description”

(p. D5) A keen sense of loss permeates “Code Black,” an affecting love letter from a young doctor to his hospital. Over the years, plenty of similar romances have been immortalized in book form, but this may be the first to play out as a documentary, and is surely the first to emerge from our newly reformed health care climate. You’d think you’d be in for some celebration.
But not in the least. In fact, among all its familiar themes, the film’s most striking is the profound sense of estrangement between the young doctors on the screen and all the recent efforts at improving the health care system. The spirit that brought them to medicine and keeps them there, they say over and over, was never even part of the national discussion.
. . .
. . . , as their department chairman points out, the day of the cowboy doctor is over; the lone commando who answers to no one and breaks rules to save patients is no longer a viable job description. Newly smothered in paperwork and quality control, many of these young doctors grieve for a self-image that has ridden off into the sunset.

For the full review, see:
ABIGAIL ZUGER, M.D.. “Saving Lives and Pushing Paper.” The New York Times (Tues., July 1, 2014): D5.
(Note: ellipses added.)
(Note: the online version of the review has the date JUNE 30, 2014.)

“Long, Lonely Odyssey “from Heresy to Orthodoxy””

MadnessAndMemoryBK2014-06-05.jpg

Source of book image: online version of the NYT review quoted and cited below.

(p. D5) As the Nobel committee put it in the 1997 citation for Dr. Prusiner’s prize in physiology or medicine, he had established “a novel principle of infection” — one so controversial that a few experts in the field still continue to search for that elusive virus. But as far as Dr. Prusiner is concerned, the Nobel confirmed that his long, lonely odyssey “from heresy to orthodoxy” was over.

The journey he details was full of hurdles. Some were of the kind likely to befall any researcher: insufficient laboratory space, poor correlation between needs and resources. (At one point, Dr. Prusiner calculated that for a single year’s worth of experiments he would have to house and feed 72,000 mice, an impossible multimillion-dollar proposition.) He submitted a grant application that was not just rejected for funding but actually “disapproved,” often the kiss of death for a train of scientific thought.
Some of his problems were a little darker but still universal — graduate students captured by competing labs, data appropriated and misrepresented by erstwhile colleagues, bitter authorship battles.
Some of Dr. Prusiner’s shoals, however, seem more particular to his personal operating style. As a teenager he was blessed with what he describes as indefatigable self-confidence, and this trait apparently endures, to the considerable irritation of others.

For the full review, see:
ABIGAIL ZUGER, M.D. “Books; A Victory Lap for a Heretical Neurologist.” The New York Times (Sat., May 20, 2014): D5.
(Note: the online version of the review has the date May 19, 2014.)

The book under review is:
Prusiner, Stanley B. Madness and Memory: The Discovery of Prions–a New Biological Principle of Disease. New Haven, CT: Yale University Press, 2014.

The Opportunity Cost of Surgeons Dictating and Documenting Health Records

(p. A13) Across the country, doctors waste precious time filling in unnecessary electronic-record fields just to satisfy a regulatory measure. I personally spend two hours a day dictating and documenting electronic health records just so I can be paid and not face a government audit. Is that the best use of time for a highly trained surgical specialist?

For the full commentary, see:
DANIEL F. CRAVIOTTO JR. “A Doctor’s Declaration of Independence; It’s time to defy health-care mandates issued by bureaucrats not in the healing profession.” The Wall Street Journal (Tues., April 29, 2014): A13.
(Note: the online version of the commentary has the date April 28, 2014.)

How Medicaid Rewards Doctors Who Mistreat Patients

(p. A13) I recently operated on a child with strabismus (crossed eyes). This child was covered by Medicaid. I was required to obtain surgical pre-authorization using a Current Procedural Terminology, or CPT, code for medical identification and billing purposes. The CPT code identified the particular procedure to be performed. Medicaid approved my surgical plan, and the surgery was scheduled.
During the surgery, I discovered the need to change my plan to accommodate findings resulting from a previous surgery by another physician. Armed with new information, I chose to operate on different muscles from the ones noted on the pre-approved plan. The revised surgery was successful, and the patient obtained straight eyes.
However, because I filed for payment using the different CPT code for the surgery I actually performed, Medicaid was not willing to adjust its protocol. The government denied all payment. Ironically, the code-listed payment for the procedure I ultimately performed was an amount 40% less than the amount approved for the initially authorized surgery. For over a year, I challenged Medicaid about its decision to deny payment. I wrote numerous letters and spoke to many Medicaid employees explaining the predicament. Eventually I gave up fighting what had obviously become a losing battle.

For the full commentary, see:
ZANE F. POLLARD. “The Bureaucrat Sitting on Your Doctor’s Shoulder; When I’m operating on a child, I shouldn’t have to wonder if Medicaid will OK a change in the surgical plan..” The Wall Street Journal (Thurs., May 22, 2014): A13.
(Note: the online version of the commentary has the date May 21, 2014.)

Government Regulations Favor Health Care Incumbents

WhereDoesItHurtBK2014-05-28.jpg

Source of book image: online version of the WSJ review quoted and cited below.

(p. A11) The rise in U.S. health-care costs, to nearly 18% of GDP today from around 6% of GDP in 1965, has alarmed journalists, inspired policy wonks and left patients struggling to find empathy in a system that tends to view them as “a vessel for billing codes,” as the technologist Dave Chase has put it.

Enter Jonathan Bush, dyslexic entrepreneur, . . .
. . .
. . . , Mr. Bush touts technology as a driver of change. It has revolutionized the way we shop for books and select hotels, but health-care delivery has been stubbornly resistant. Mr. Bush notes that the number of people supporting each doctor has climbed to 16 today from 10 in 1990–half of whom, currently, are administrators handling the mounting paperwork. Astonishingly, as Mr. Bush observes, the government had to pay doctors billions of dollars, via the 2009 HITECH Act, to incentivize them to upgrade from paper to computers. Meanwhile, fast-food chains discovered computers on their own, because the market demanded it.
. . .
Let entrepreneurs loose on these challenges, Mr. Bush believes, and they will come up with solutions.
Mr. Bush identifies three major obstacles to the kinds of change he has in mind. First, large hospital systems leverage their market position to charge hefty premiums for basic services, then use the proceeds to buy more regional hospitals and local practices. “As big ones take over the small,” Mr. Bush laments, “prices shoot up. Choices vanish.” Second, government regulations, especially state laws, favor powerful incumbents, shielding “imaging centers and hospitals from competition.” Third, heath care suffers from a risk-avoidant culture. The maxim “do no harm,” Mr. Bush says, should not be an excuse for clinging to a flawed status quo.

For the full review, see:
David A. Shaywitz. “BOOKSHELF; A System Still in Need of Repair; Routine medical services can be done for less cost–one of many obvious realities that current health-care practices studiously ignore.” The Wall Street Journal (Mon., May 19, 2014): A11.
(Note: ellipses added.)
(Note: the online version of the review has the date May 18, 2014, and has the title “BOOKSHELF; Book Review: ‘Where Does It Hurt?’ by Jonathan Bush; Routine medical services can be done for less cost–one of many obvious realities that current health-care practices studiously ignore.”)

The book under review is:
Bush, Jonathan, and Stephen Baker. Where Does It Hurt?: An Entrepreneur’s Guide to Fixing Health Care. New York: Portfolio, 2014.

Young Inca Woman Was Probably Murdered

MurderedIncanYoungWoman2014-04-28.jpg “The Incan mummy.” Source of caption and photo: online version of the NYT article quoted and cited below.

Hobbes famously wrote that for most of human existence, life has been “poor, nasty, brutish, and short.” Further evidence:

(p. D4) Scientists who have examined the mummy of a young Inca say that her death was most likely a homicide and that it was not because of Chagas disease, the tropical parasitic infection that she had.

For the full story, see:
“Observatory; A Verdict of Murder.” The New York Times (Tues., MARCH 4, 2014): D4.
(Note: the online version of the story has the date MARCH 3, 2014.)

The famous Hobbes quote can be found on p. 70 of:
Hobbes, Thomas. Leviathan, Dover Philosophical Classics. Mineola, New York: Dover Publications, Inc., 2006 [first published 1651].

Crispr Molecular System Allows Scientists to Edit Genes

CrisprEditsGenes2014-04-28.jpgSource of graph: online version of the NYT article quoted and cited below.

(p. D1) In the late 1980s, scientists at Osaka University in Japan noticed unusual repeated DNA sequences next to a gene they were studying in a common bacterium. They mentioned them in the final paragraph of a paper: “The biological significance of these sequences is not known.”
Now their significance is known, and it has set off a scientific frenzy.
The sequences, it turns out, are part of a sophisticated immune system that bacteria use to fight viruses. And that system, whose very existence was unknown until about seven years ago, may provide scientists with unprecedented power to rewrite the code of life.
In the past year or so, researchers have discovered that the bacterial system can be harnessed to make precise changes to the DNA of humans, as well as other animals and plants.
This means a genome can be edited, much as a writer might change words or fix spelling errors. It allows “customizing the genome of any cell or any species at will,” said Charles Gersbach, an assistant professor of biomedical engineering at Duke University.

For the full story, see:
ANDREW POLLACK. “A Powerful New Way to Edit DNA.” The New York Times (Tues., MARCH 4, 2014): D1 & D5.
(Note: the online version of the story has the date MARCH 3, 2014.)

30,000 Year Old Virus Revived from Permafrost

(p. D5) From Siberian permafrost more than 30,000 years old, [French and Russian researchers] have revived a virus that’s new to science.
“To pull out a virus that’s 30,000 years old and actually grow it, that’s pretty impressive,” said Scott O. Rogers of Bowling Green State University who was not involved in the research. “This goes well beyond what anyone else has done.”
. . .
Measuring 1.5 micrometers long, the viruses are 25 percent bigger than any virus previously found.
. . .
“Sixty percent of its gene content doesn’t resemble anything on earth,” Dr. Abergel said. She and her colleagues suspect that pithoviruses may be parasitic survivors of life forms that were very common early in the history of life.
. . .
“Its potential implications for evolutionary theory and health are quite astonishing,” said Eske Willerslev, an evolutionary biologist at the University of Copenhagen.

For the full story, see:
Carl Zimmer. “Out of Siberian Ice, a Virus Revived.” The New York Times (Tues., MARCH 4, 2014): D5.
(Note: ellipses, and bracketed words, added.)
(Note: the online version of the story has the date MARCH 3, 2014.)

In France “‘Liberté, Égalité, Fraternité’ Means that What’s Yours Should Be Mine”

SantacruzGuillaumeFrenchEntrepreneurInLondon2014-04-27.jpgGuillaume Santacruz is among many French entrepreneurs now using London as their base. He said of his native France, “The economy is not going well, and if you want to get ahead or run your own business, the environment is not good.” Source of caption and photo: online version of the NYT article quoted and cited below.

(p. 1) Guillaume Santacruz, an aspiring French entrepreneur, brushed the rain from his black sweater and skinny jeans and headed down to a cavernous basement inside Campus London, a seven-story hive run by Google in the city’s East End.
. . .
A year earlier, Mr. Santacruz, who has two degrees in finance, was living in Paris near the Place de la Madeleine, working in a boutique finance firm. He had taken that job after his attempt to start a business in Marseille foundered under a pile of government regulations and a seemingly endless parade of taxes. The episode left him wary of starting any new projects in France. Yet he still hungered to be his own boss.
He decided that he would try again. Just not in his own country.
“A lot of people are like, ‘Why would you ever leave France?’ ” Mr. Santacruz said. “I’ll tell you. France has a lot of problems. There’s a feeling of gloom that seems to be growing deeper. The economy is not going well, and if you want to get ahead or run your own business, the environment is not good.”
. . .
(p. 5) “Making it” is almost never easy, but Mr. Santacruz found the French bureaucracy to be an unbridgeable moat around his ambitions. Having received his master’s in finance at the University of Nottingham in England, he returned to France to work with a friend’s father to open dental clinics in Marseille. “But the French administration turned it into a herculean effort,” he said.
A one-month wait for a license turned into three months, then six. They tried simplifying the corporate structure but were stymied by regulatory hurdles. Hiring was delayed, partly because of social taxes that companies pay on salaries. In France, the share of nonwage costs for employers to fund unemployment benefits, education, health care and pensions is more than 33 percent. In Britain, it is around 20 percent.
“Every week, more tax letters would come,” Mr. Santacruz recalled.
. . .
Diane Segalen, an executive recruiter for many of France’s biggest companies who recently moved most of her practice, Segalen & Associés, to London from Paris, says the competitiveness gap is easy to see just by reading the newspapers. “In Britain, you read about all the deals going on here,” Ms. Segalen said. “In the French papers, you read about taxes, more taxes, economic problems and the state’s involvement in everything.”
. . .
“It is a French cultural characteristic that goes back to almost the revolution and Robespierre, where there’s a deep-rooted feeling that you don’t show that you make money,” Ms. Segalen, the recruiter, said. “There is this sense that ‘liberté, égalité, fraternité’ means that what’s yours should be mine. It’s more like, if someone has something I can’t have, I’d rather deprive this person from having it than trying to work hard to get it myself. That’s a very French state of mind. But it’s a race to the bottom.”

For the full story, see:
LIZ ALDERMAN. “Au Revoir, Entrepreneurs.” The New York Times, SundayBusiness Section (Sun., MARCH 23, 2014): 1 & 5.
(Note: ellipses added.)
(Note: the online version of the story has the date MARCH 22, 2014.)

SegalenDianeFrenchEntrepreneurInLondon2014-04-27.jpg ‘Diane Segalen moved most of her executive recruiting practice to London from Paris. In France, she says, “there is this sense that ‘liberté, égalité, fraternité’ means that what’s yours should be mine.”” Source of caption and photo: online version of the NYT article quoted and cited above.