(p. D2) Once there was a mutant worm in an experiment. It lived for 46 days. This was much longer than the oldest normal worm, which lived just 22.
Researchers identified the mutated gene that had lengthened the worm’s life, which led to a breakthrough in the study of aging — it seemed to be controlled by metabolic processes. Later, as researchers studied these processes, all signs seemed to point to the nucleolus.
. . .
“We think the nucleolus plays an important role in regulating the life span of animals,” said Adam Antebi, a cellular biologist at the Max Planck Institute for Biology of Ageing in Germany. He’s an author of a new review published last week in Trends in Cell Biology that examines all the new ways that researchers have fallen in love with the nucleolus — especially its role in aging.
For the full story see:
(Note: ellipsis added.)
(Note: the online version of the story has the date May 20, 2018 [sic], and has the title “The Thing Inside Your Cells That Might Determine How Long You Live.”)
The academic study of the role of the nucleolus in extending lifespans, mentioned above, is: