Category: Covid-19

Chinese Scientists “Withdrew” Research Paper That Noted Proximity of Shi Bat Lab to Wuhan Market

(p. A11) For the past 15 years, Chinese scientist Shi Zhengli has warned the world—in English, Chinese and French—that bats harbor coronaviruses that pose serious risks to human health.

The flying mammals are a likely culprit in the pandemic now sweeping the globe, and Dr. Shi and her laboratories in Wuhan, where the outbreak was first identified, have attracted suspicion.

. . .

Dr. Shi’s experience—and her large set of reference material—helped her determine that the new coronavirus loose in Wuhan had most likely come from a bat. In fact, a sample her team collected in Yunnan province in 2013 was about 96% identical to the genetic sequence of the virus that causes Covid-19.

All of that has raised questions about whether the virus could have somehow escaped from one of Dr. Shi’s labs and infected Wuhan’s population.

In a February [2020] research paper, Chinese scientists pointed out that the Wuhan market, where the coronavirus began spreading late last year, was close to her labs as well as those of another local scientist who has worked on bats at the Wuhan Municipal Centers for Disease Control and Prevention.

The authors withdrew their paper as “speculation” after it got widespread international notice.

For the full story, see:

James T. Areddy. “‘Bat Woman’ Draws Scrutiny.” The Wall Street Journal (Wednesday, April 22, 2020): A11.

(Note: ellipsis, and bracketed year, added.)

(Note: the online version of the story has the date April 21, 2020, and has the title “China Bat Expert Says Her Wuhan Lab Wasn’t Source of New Coronavirus.”)

Early Promising Results from Gilead-Sponsored Study on Remdesivir

(p. B3) A doctor in Chicago told colleagues that Gilead’s drug remdesivir appeared to help many patients enrolled in a clinical trial site at the University of Chicago Medicine hospital, according to a news report in online health publication STAT, which cited a video of the remarks. The doctor said that the hospital had enrolled 125 patients in two remdesivir studies sponsored by Gilead, and that most had been discharged from the hospital, and two had died.

. . .

“Partial data from an ongoing clinical trial is by definition incomplete and should never be used to draw conclusions about the safety or efficacy of a potential treatment that is under investigation,” a University of Chicago spokeswoman said in an email. “Drawing any conclusions at this point is premature and scientifically unsound.”

. . .

Last week, Gilead reported in the New England Journal of Medicine that remdesivir showed encouraging results in treating 53 patients with severe Covid-19 symptoms. The patients were given the drug under so-called compassionate use, which allows for doctors to request unapproved drugs for patients in emergency situations.

Of the 53 compassionate use patients who received remdesivir, nearly half were discharged from the hospital and seven patients died, or 13% of the total, according to the New England Journal paper. Of 30 patients using breathing tubes connected to ventilators, 17 had their tubes disconnected after remdesivir treatment.

For the full story, see:

Joseph Walker. “Gilead Shares Up 9.7% On Encouraging Signs In Covid-19 Drug Trial.” The Wall Street Journal (Saturday, April 18, 2020): B3.

(Note: ellipses added.)

(Note: the online version of the story has the date April 17, 2020, and has the title “Coronavirus Drug Report, Though Inconclusive, Sends Gilead Higher.” Where the versions differ, the passages quoted above follow the somewhat longer online version.)

Chinese Communists Censor Academic Articles on Origins of Covid-19

(p. A21) Beijing has claimed that the virus originated in a Wuhan “wet market,” where wild animals were sold. But evidence to counter this theory emerged in January [2020]. Chinese researchers reported in the Lancet Jan. 24 that the first known cases had no contact with the market, and Chinese state media acknowledged the finding. There’s no evidence the market sold bats or pangolins, the animals from which the virus is thought to have jumped to humans. And the bat species that carries it isn’t found within 100 miles of Wuhan.

Wuhan has two labs where we know bats and humans interacted. One is the Institute of Virology, eight miles from the wet market; the other is the Wuhan Center for Disease Control and Prevention, barely 300 yards from the market.

Both labs collect live animals to study viruses. Their researchers travel to caves across China to capture bats for this purpose. Chinese state media released a minidocumentary in mid-December following a team of Wuhan CDC researchers collecting viruses from bats in caves. The researchers fretted openly about the risk of infection.

. . .

While the Chinese government denies the possibility of a lab leak, its actions tell a different story. The Chinese military posted its top epidemiologist to the Institute of Virology in January. In February Chairman Xi Jinping urged swift implementation of new biosafety rules to govern pathogens in laboratory settings. Academic papers about the virus’s origins are now subject to prior restraint by the government.

For the full commentary, see:

Tom Cotton. “Coronavirus and the Laboratories in Wuhan.” The Wall Street Journal (Wednesday, April 22, 2020): A21.

(Note: ellipsis, and bracketed year, added.)

(Note: the online version of the commentary has the date April 21, 2020, and has the title “ON BUSINESS; Airbnb Defied the Odds of Startup Success. How Will It Survive a Pandemic?”)

Firm Founders “Learned to Cope With a Lot of Adversity and Have a Lot of Resilience”

(p. B6) I’m a sucker for good stories about the founding of companies.

Yvon Chouinard started apparel maker Patagonia in a chicken coop; James Dyson went through 5,000 prototypes on his way to inventing a bagless vacuum cleaner; Steve Ellis opened Chipotle burrito shops simply to earn enough money to start a gourmet restaurant (he never got that far).

Airbnb Inc.’s story takes the cake. In 2008, a couple entrepreneurial types living on Ramen noodles in San Francisco cooked up an online home-sharing scheme. They recruited a computer scientist, funded their idea in the early days by maxing out credit cards and selling politically-themed cereal boxes, and held on until their company shook up the entire lodging industry.

. . .

“There’s this crazy idealism that founders have,” Brian Chesky, one of those Airbnb founders and the company’s chief executive, told me this week in a video chat. “They’ve learned to cope with a lot of adversity and have a lot of resilience.”

For the full commentary, see:

John D. Stoll. “ON BUSINESS; Airbnb Defied the Startup Odds. Will It Survive a Pandemic?” The Wall Street Journal (Saturday, April 18, 2020): B6.

(Note: ellipsis added.)

(Note: the online version of the commentary has the date April 17, 2020, and has the title “ON BUSINESS; Airbnb Defied the Odds of Startup Success. How Will It Survive a Pandemic?”)

Small Is Not Always Beautiful

(p. A16) Zaid Kurdieh has so many fava beans growing at his farm in upstate New York that he could send 4,000 pounds a week to the best chefs in New York City. In Kentucky, Robert Eversole and Thomas Sargent planted enough winter greens to fill the all the salad bars at the University of Kentucky and still have enough left over to feed fans at the state’s two major spring horse races.

But the coronavirus pandemic has postponed the Kentucky Derby and shut the university. And in New York, chefs who would normally be shelling Mr. Kurdieh’s fava beans for their spring menus have closed their restaurants.

So these small farmers, like many others across the country who spent decades building a local, sustainable agricultural system, are staring at their fields and wondering what to do now that the table has been kicked out from under the modern farm-to-table movement.

. . .

Farm-to-table — the term has become a fixture in the culinary lexicon — started in the 1970s, when Chez Panisse and a handful of other restaurants hatched what then seemed like a radical notion: Build menus from food grown by nearby farmers who are thoughtful about everything from the seeds they select and the soil they grow them in to the communities they feed.

That idea grew into a pipeline connecting farmers, ranchers and chefs that in 2019 had generated $12 billion in income for small-scale producers including cheesemakers and vintners. Governments, hospitals and schools have come to see the value in buying locally grown food. No Silicon Valley tech company worth its stock price would dare to design a cafeteria without local food.

Since the pandemic hit, that conduit has shut down. The loss in sales could run as high as $689 million, with much higher costs in jobs and other businesses that make up the farm-to-table economic ecosystem, according to a report compiled in March by the National Sustainable Agriculture Coalition.

For the full story, see:

Kim Severson. “Farm-to-Table Falters, and Growers Are in Limbo.” The New York Times (Friday, April 10, 2020): A16.

(Note: ellipsis added.)

(Note: the online version of the story has the date April 9, 2020, and has the title “The Farm-to-Table Connection Comes Undone.”)

An Informed Public Can Protect Themselves Better than Central Planners Can Protect Them

(p. A15) China teaches one thing: When a novel respiratory virus emerges, a free press is on balance an indispensable medical asset. The steps an informed public can take to protect itself are far more potent than any top-down action. Unknown is whether the new disease really originated in a meat market in Wuhan, as was first reported. But suppressing news of its outbreak once it was discovered was China’s most fatal mistake.

For the full commentary, see:

Holman W. Jenkins, Jr. “BUSINESS WORLD; Coronavirus Needs a Free Press.” The Wall Street Journal (Wednesday, February 12, 2020): A15.

(Note: the online version of the commentary has the date Feb. 11, 2020, and has the same title as the print version.)

A Map as Large as the Territory It Represents

(p. A4) As more reliable data comes in, said Dr. Spiegelhalter, “the Covid-19 pandemic is rapidly becoming a constrained problem.”

. . .

Statistical science, he said, “is a machine, in a sense, to turn the variability that we see in the world — the unpredictability, the enormous amount of scatter and randomness that we see around us — into a tool that can quantify our uncertainty about facts and numbers and science.”

But as he acknowledged in his book, “The Art of Statistics,” models “are simplifications of the real world — they are the maps not the territory.” (This is reminiscent of Jorge Luis Borges’s story, “On Exactitude in Science,” about a map growing as large as the territory it was meant to represent.)

For the full review, see:

Siobhan Roberts. “Embracing the Uncertainties of the Pandemic.” The New York Times (Wednesday, April 8, 2020): A4.

(Note: ellipsis added.)

(Note: the online version of the review has the date April 7, and has the title “Embracing the Uncertainties.”)

The Spiegelhalter book mentioned above, is:

Spiegelhalter, David. The Art of Statistics: How to Learn from Data. New York: Basic Books, 2019.

Each Week, Chinese Children Read “Socialism Is Good. Capitalism Is Bad.”

(p. A11) Many Chinese children of my generation read a newspaper column for students called “Socialism Is Good. Capitalism Is Bad.” Each week, it described the wonders of China alongside the hardships of capitalist societies. The lesson: Socialist China takes care of its people, while people in the United States go hungry and the elderly die alone.

For the full commentary, see:

Li Yuan. “THE NEW NEW WORLD; China Builds Culture of Hate With Selective Coverage of the Pandemic.” The New York Times (Thursday, April 23, 2020): A11.

(Note: the online version of the commentary has the date April 22, 2020, and has the title “THE NEW NEW WORLD; With Selective Coronavirus Coverage, China Builds a Culture of Hate.”)

Since SARS, Japanese Protect One Another by Wearing Masks

(p. A4) PARIS — Until a few weeks ago, Asian tourists were the only mask-wearers in Paris, eliciting puzzlement or suspicion from French locals, or even hostility as the coronavirus began sweeping across Europe.

. . .

This taboo is falling fast, not only in France but across Western countries, after mounting cries from experts who say the practice is effective in curbing the coronavirus pandemic.

The shift for Western nations is profound and has had to overcome not merely the logistical challenges of securing enough masks, which are significant enough, but also a deep cultural resistance and even stigma associated with mask-wearing, which some Western leaders described flatly as “alien.”

Seemingly, it won’t be for much longer. After discouraging people from wearing face masks, France, like the United States, has begun urging its citizens to wear basic or homemade ones outside. And some parts of Europe are moving faster than the United States by requiring masks instead of simply recommending their use.

. . .

. . . masks were . . . alien to Asia until it was struck by the SARS pandemic in 2003.

In Japan, after people got used to masks, they continued to wear them against seasonal allergies or to protect one another from germs. Unlike in other Asian nations, where many wear masks against air pollution, mask-wearing became widespread despite the absence of immediate threats.

Mask-wearing has become such a part of daily life that it now plays a role in maintaining an overall feeling of being “reassured” in Japanese society, said Yukiko Iida, an expert on masks at the Environmental Control Center, an environmental consulting company based in Tokyo.

“When you put on a mask, you’re not inconveniencing others when you cough,” Ms. Iida said. “You’re showing others that you’re abiding by social etiquette, and so people feel reassured.”

. . .

Daniel Illouz, a pharmacist in eastern Paris, said that he had been skeptical of the government’s repeated message that widespread mask-wearing was not helpful in fighting the epidemic.

“I don’t see why in all the Asian countries, where they have masks, it would work, but it wouldn’t work for us,” he said.

For the full story, see:

Norimitsu Onishi and Constant Méheut. “Wearing Masks, Common in Asia, Rises in the West.” The New York Times (Friday, April 10, 2020): A4.

(Note: ellipses added.)

(Note: the online version of the story has the date April 9, 2020, and has the title “Mask-Wearing Is a Very New Fashion in Paris (and a Lot of Other Places).”)

Hospitals Punish Workers Who Expose Management Failures

(p. B5) In New York City, the epicenter of the crisis in the United States, every major private hospital system has sent memos in recent weeks ordering workers not to speak with the media, as have some public hospitals.

One system, NYU Langone Medical Center, which has more than 30,000 employees at six inpatient centers, dozens of outpatient facilities and the New York University School of Medicine, sent an email on March 27 [2020] warning that staff members speaking to the media without permission “will be subject to disciplinary action, including termination.” The email was reported earlier by Bloomberg.

Administrators suggested “appropriate” posts on social media instead. “Please share positive and uplifting messages that support your colleagues and our organization,” they said in another email.

Similar lines are being drawn nationwide. A doctor in Washington State was removed from his hospital position after speaking publicly about a shortage of protective equipment and testing; the staffing firm that employs him said he was being reassigned. Nurses in Detroit recently walked off the job to protest critically low staffing after a colleague who had spoken up on the issue was fired.

For the full story, see:

Noam Scheiber and Brian M. Rosenthal. “Nurse Questions Hospital On Safety. He’s Out a Job.” The New York Times (Friday, April 10, 2020): B1 & B5.

(Note: bracketed year added.)

(Note: the online version of the story was updated April 15, 2020, and has the title “Nurses and Doctors Speaking Out on Safety Now Risk Their Job.”)

Entrepreneurially Nimble Amish Pivot to Make Face Masks

(p. A9) SUGARCREEK, Ohio — On April 1, John Miller, a manufacturer here with deep connections to the close-knit Amish community of Central Ohio, got a call from Cleveland Clinic. The hospital system was struggling to find protective face masks for its 55,000 employees, plus visitors. Could his team sew 12,000 masks in two days?

He appealed to Abe Troyer with Keim, a local lumber mill and home goods business and a leader in the Amish community: “Abe, make a sewing frolic.” A frolic, Mr. Miller explained, “is a colloquial term here that means, ‘Get a bunch of people. Throw a bunch of people at this.’”

A day later, Mr. Troyer had signed up 60 Amish home seamstresses, and the Cleveland Clinic sewing frolic was on.

. . .

Almost overnight, a group of local industry, community and church leaders has mobilized to sustain Amish households by pivoting to work crafting thousands of face masks and shields, surgical gowns and protective garments from medical-grade materials. When those run scarce, they switch to using gaily printed quilting fabric and waterproof Tyvek house wrap.

For the full story, see:

Elizabeth Williamson. “In Ohio, Amish Families Pivot to Make Medical Gear.” The New York Times (Friday, April 10, 2020): A9.

(Note: ellipsis added.)

(Note: the online version of the story was updated April 16, 2020, and has the title “In Ohio, the Amish Take On the Coronavirus.”)