Costs of Covid Lockdowns and Mask Mandates Exceeded Benefits

(p. A15) The Centers for Disease Control and Prevention belatedly admitted failure this week. “For 75 years, CDC and public health have been preparing for Covid-19, and in our big moment, our performance did not reliably meet expectations,” Director Rochelle Walensky said. She vowed to establish an “action-oriented culture.”

. . .

U.S. states with more-restrictive policies fared no better, on average, than states with less-restrictive policies. There’s still no convincing evidence that masks provided any significant benefits. When case rates throughout the pandemic are plotted on a graph, the trajectory in states with mask mandates is virtually identical to the trajectory in states without mandates. (The states without mandates actually had slightly fewer Covid deaths per capita.) International comparisons yield similar results. A Johns Hopkins University meta-analysis of studies around the world concluded that lockdown and mask restrictions have had “little to no effect on COVID-19 mortality.”

. . .

In 2006 he and colleagues at the University of Pittsburgh considered an array of proposed measures to deal with a virus as deadly as the 1918 Spanish flu.

Should schools be closed? Should everyone wear face masks in public places? Should those exposed to an infection be required to quarantine at home? Should public-health officials rely on computer models of viral spread to impose strict limitations on people’s movements? In each case, the answer was no, because there was no evidence these measures would make a significant difference.

“Experience has shown,” Henderson’s team concluded, “that communities faced with epidemics or other adverse events respond best and with the least anxiety when the normal social functioning of the community is least disrupted.” The researchers specifically advised leaders not to be guided by computer models, because no model could reliably predict the effects of the measures or take into account the “devastating” collateral damage. If leaders overreacted and panicked the public, “a manageable epidemic could move toward catastrophe.”

This advice was subsequently heeded in the pre-Covid pandemic plans prepared by the CDC and other public-health agencies. The WHO’s review of the scientific literature concluded that there was “no evidence” that universal masking “is effective in reducing transmission.” The CDC’s pre-2020 planning scenarios didn’t recommend universal masking or extended school and business closures even during a pandemic as severe as the 1918 Spanish flu.

For the full commentary see:

John Tierney. “Fauci and Walensky Double Down on Failure.” The Wall Street Journal (Friday, Aug. 19, 2022): A15.

(Note: ellipses added.)

(Note: the online version of the commentary has the date August 18, 2022, and has the title “Fauci and Walensky Double Down on Failed Covid Response.”)

Human Challenge Trial Sped Phase 3 of Typhoid Vaccine Clinical Trial

Observers Give Thumbs-Up to Matthew Speight as He Prepared to Drink Typhoid Bacteria as Part of a Human Challenge Trial.
Source of Image: NYT commentary cited below.

(p. D3) “I was curious.” That’s how James M. Duggan, an Oxford University medical student, explains why he agreed to swallow a big dose of live typhoid bacteria.

. . .

Mr. Duggan, 33, was not on a self-destructive sympathy bender. Like more than 100 other residents of Oxford, England, he was taking part in a trial of a new typhoid vaccine.

Typhoid fever, caused by the bacteria Salmonella typhi and spread in food and water, kills almost 200,000 victims a year — many of them young children — in Africa, Asia and Latin America. Survivors may suffer perforated intestines, heart problems and other complications.

The experimental vaccine was a big success. The trial’s results were published in The Lancet on Thursday [Sept. 28, 2017]: the vaccine turned out to be 87 percent effective.

. . .

“These are great results,” said Dr. Anita Zaidi, the foundation’s director of diarrheal diseases. “And challenge tests are a great way to short-circuit the process of proving it works.

“If we’d done this in the field, we would have had to follow children for three or four years.”

So-called challenge tests involve giving subjects an experimental vaccine and then deliberately infecting them with the disease to see if it protects them.

These tests can only be done with illnesses — like cholera or malaria — that can be rapidly and completely cured, or with diseases — like seasonal flu — that normally do not damage healthy adults.

. . .

So what would motivate dozens of well-educated Britons to swallow a vial full of the germs that made Typhoid Mary famous? In interviews, they gave various reasons.

Some, like Mr. Duggan, were curious. Some wanted to help poor people. And some mostly wanted the cash.

Participants who followed all the steps, which included recording their temperatures online, making daily clinic visits and providing regular blood and stool samples, received about $4,000.

They all said they understood the risks.

For the full commentary see:

Donald G. McNeil Jr. “Curiosity, and Cash, Fight a Fever.” The New York Times (Tuesday, October 3, 2017): D3.

(Note: ellipses, and bracketed date, added.)

(Note: the online version of the commentary has the date Sept. 28, 2017, and has the title “They Swallowed Live Typhoid Bacteria — On Purpose.”)

The print version of The Lancet article mentioned above is:

Jin, Celina, Malick M. Gibani, Maria Moore, Helene B. Juel, Elizabeth Jones, James Meiring, Victoria Harris, Jonathan Gardner, Anna Nebykova, Simon A. Kerridge, Jennifer Hill, Helena Thomaides-Brears, Christoph J. Blohmke, Ly-Mee Yu, Brian Angus, and Andrew J. Pollard. “Efficacy and Immunogenicity of a Vi-Tetanus Toxoid Conjugate Vaccine in the Prevention of Typhoid Fever Using a Controlled Human Infection Model of Salmonella Typhi: A Randomised Controlled, Phase 2b Trial.” The Lancet 390, no. 10111 (Dec. 2, 2017): 2472-80.

Leftist Anti-Covid-Vaccine Roman Catholic Nun Defends Free Speech

(p. A12) MONTSERRAT, Spain — Sister Teresa Forcades came to public notice years ago for her unflinching liberal views: an outspoken Roman Catholic nun whose pronouncements ran counter to the church’s positions on same-sex marriage and abortion.

She became a fixture on Spanish television, appearing in her nun’s habit to advocate independence for her native region of Catalonia, and to debate other hot-button topics, including vaccines. She had trained as a doctor, partly in the United States, and argued that vaccinations might one day pose a danger to a free society.

. . .

“It’s always important that criticism is possible, to have dissenting voices,” she said of her views, which center as much on her doubts about the vaccines as her right to question them in public. “The answer cannot be that in the time of a crisis, society cannot allow the criticism — it’s precisely then that we need it.”

. . .

In the world of vaccine skeptics, Sister Teresa, who was born in 1966 to a nurse and a commercial agent, is hard to categorize. She acknowledges that some vaccines are beneficial, but opposes making them mandatory. Her misgivings about coronavirus vaccines largely stem from her view that pharmaceutical companies are not to be trusted, and the clinical trials were rushed.

. . .

Sister Teresa, though staunchly leftist, doesn’t distance herself from right-wing followers, calling her distrust of some vaccines a “transversal question able to reach a wide spectrum of people.”

For the full story see:

Nicholas Casey. “Spanish Nun With Medical Training Champions Vaccine Distrust.” The New York Times (Saturday, April 24, 2021): A12.

(Note: ellipses added.)

(Note: the online version of the article has the date April 23, 2021, and has the title “A Nun and a Doctor, She’s One of Europe’s Longstanding Vaccine Skeptics.”

Those Who Survived Dictatorship Know We Need “More Freedom, More Speech, Not Less”

(p. A19) The left’s reaction to Mr. Trump’s rhetoric was instructive. Anyone who mentioned the lab-leak theory was assailed as pro-Trump. Social-media companies removed posts mentioning it. By January 2021, it was obvious that shutting down debate was the true antiscience position. Invaluable months were lost, time the Chinese Communist Party used to destroy data and spread disinformation about the virus’s origins. We may never know the truth, but we do know there was a coverup.

Increasing numbers of Americans believe their freedom is under attack, and I agree. . . .

Schools are being pressured to remove books and cancel professors for spreading the “wrong” ideas. These sentiments are all too familiar to me, and to anyone who has survived life in a dictatorship. The only answer is more freedom, more speech, not less.

For the full commentary see:

Garry Kasparov. “‘Woke’ Is a Bad Word for a Real Threat to American Democracy.” The Wall Street Journal (Thursday, Nov. 18, 2021): A19.

(Note: ellipsis added.)

(Note: the online version of the commentary has the date November 17, 2021, and has the same title as the print version.

“Paradox”: “Masks Work and Mask Mandates Do Not Work”

(p. A19) The Evidence

From the beginning of the pandemic, there has been a paradox involving masks. As Dr. Shira Doron, an epidemiologist at Tufts Medical Center, puts it, “It is simultaneously true that masks work and mask mandates do not work.”

To start with the first half of the paradox: Masks reduce the spread of the Covid virus by preventing virus particles from traveling from one person’s nose or mouth into the air and infecting another person. Laboratory studies have repeatedly demonstrated the effect.

Given this, you would think that communities where mask-wearing has been more common would have had many fewer Covid infections. But that hasn’t been the case.

In U.S. cities where mask use has been more common, Covid has spread at a similar rate as in mask-resistant cities. Mask mandates in schools also seem to have done little to reduce the spread. Hong Kong, despite almost universal mask-wearing, recently endured one of the world’s worst Covid outbreaks.

Advocates of mandates sometimes argue that they do have a big effect even if it is not evident in populationwide data, because of how many other factors are at play. But this argument seems unpersuasive.

After all, the effect of vaccines on severe illness is blazingly obvious in the geographic data: Places with higher vaccination rates have suffered many fewer Covid deaths. The patterns are clear even though the world is a messy place, with many factors other than vaccines influencing Covid death rates.

Yet when you look at the data on mask-wearing — both before vaccines were available and after, as well as both in the U.S. and abroad — you struggle to see any patterns.

Almost 30 Percent

The idea that masks work better than mask mandates seems to defy logic. It inverts a notion connected to Aristotle’s writings: that the whole should be greater than the sum of the parts, not less.

The main explanation seems to be that the exceptions often end up mattering more than the rule. The Covid virus is so contagious that it can spread during brief times when people take off their masks, even when a mandate is in place.

For the full commentary see:

David Leonhardt. “Masks Work, So Why Haven’t Mandates Made Much Difference?” The New York Times (Wednesday, June 1, 2022): A19.

(Note: the headings appeared in bold in the original.)

(Note: the online version of the commentary has the date May 31, 2021, and has the title “Why Masks Work, but Mandates Haven’t.”

Corrupt Crony “Emergent” Firm Emerges as Incompetent Too

Emergent’s role in crony capitalism was documented in an earlier entry, that documented the donations and lobbying gifts they bestowed on congress and regulators in order to fill the emergency health stockpile with dubious anthrax vaccine instead of the masks and ventilators that were in demand during the Covid-19 pandemic.

(p. A7) WASHINGTON — Workers at a plant in Baltimore manufacturing two coronavirus vaccines accidentally conflated the ingredients several weeks ago, contaminating up to 15 million doses of Johnson & Johnson’s vaccine and forcing regulators to delay authorization of the plant’s production lines.

The plant is run by Emergent BioSolutions, a manufacturing partner to both Johnson & Johnson and AstraZeneca, the British-Swedish company whose vaccine has yet to be authorized for use in the United States. Federal officials attributed the mistake to human error.

. . .

The mistake is a major embarrassment both for Johnson & Johnson, whose one-dose vaccine has been credited with speeding up the national immunization program, and for Emergent, its subcontractor, which has faced fierce criticism for its heavy lobbying for federal contracts, especially for the government’s emergency health stockpile.

For the full story see:

Sharon LaFraniere and Noah Weiland. “Factory Mix-Up Ruins 15 Million Doses Of Vaccine From Johnson & Johnson.” The New York Times (Thursday, April 1, 2021): A7.

(Note: ellipsis added.)

(Note: the online version of the article was updated Aug. [sic] 1, 2021, and has the title “Factory Mix-Up Ruins Up to 15 Million Vaccine Doses From Johnson & Johnson.”

Covid Lockdowns “Embolden” Invasive Species and Wildlife Poaching

(p. 1) In a typical spring, breeding seabirds — and human seabird-watchers — flock to Stora Karlsö, an island off the coast of Sweden.

That might seem like a tidy parable about how nature recovers when people disappear from the landscape — if not for the fact that ecosystems are complex. The newly numerous eagles repeatedly soared past the cliffs where a protected population of common murres laid its eggs, flushing the smaller birds from their ledges.

In the commotion, some eggs tumbled from the cliffs; others were snatched by predators while the murres were away. The murres’ breeding performance dropped 26 percent, Jonas Hentati-Sundberg, a marine ecologist at the Swedish University of Agricultural Sciences, found. “They were flying out in panic, and they lost their eggs,” he said.

. . .

(p. 6) Multiple studies found that as traffic eased in the spring of 2020, the number of wild animals that were struck and killed by cars declined. But the number of wildlife-vehicle collisions soon crept back up, even as traffic remained below normal levels, one team of researchers reported.

“Per mile driven, there were more accidents happening during the pandemic, which we interpreted as changes in animal space use,” said Joel Abraham, a graduate student studying ecology at Princeton University and an author of the study. “Animals started using roads. And it was difficult for them to stop, even when traffic started to rebound.”

The lockdowns seemed to embolden some invasive species, increasing the daytime activity of Eastern cottontail rabbits in Italy, where their rapid expansion may threaten native hares, while disrupting efforts to control others.

. . .

Spikes in wildlife poaching and persecution, as well as illegal logging and mining, were reported in multiple countries.

Economic insecurity might have driven some of this activity, but experts believe that it was also made possible by lapses in human protection, including reduced staffing in parks and preserves and even an absence of tourists, whose presence might typically discourage illegal activity.

“We’re not entirely the bad guys,” said Mitra Nikoo, a research assistant at the University of Victoria. “We’re actually doing a lot more good than we’ve been giving ourselves credit for.”

For the full story see:

Emily Anthes. “‘Anthropause’ During Pandemic Healed Nature, but Hurt It, Too.” The New York Times, First Section (Sunday, July 17, 2022): 1 & 6.

(Note: ellipses added.)

(Note: the online version of the story was updated July 21, 2022, and has the title “Did Nature Heal During the Pandemic ‘Anthropause’?”)

Government Sends Town’s $360,000 Covid Relief Funds to 24-Year-Old Who Loses It All at Online Casinos

(p. A4) TOKYO — Residents of a rural Japanese town were each looking forward to receiving a $775 payment last month as part of a coronavirus pandemic stimulus program.

But a municipal official mistakenly wired the town of Abu’s entire Covid relief budget, nearly $360,000, to a single recipient on the list of low-income households eligible to receive the money. After promising to return the accidental payment, the police said, the man gambled it away.

The man, Sho Taguchi, 24, told the police that he had lost the money in online casinos, a police official in Yamaguchi Prefecture said by phone on Thursday [May 19, 2022]. The day before, the authorities arrested Mr. Taguchi, the official said. The charge: fraud.

Japan is not the only country where coronavirus relief money has been misappropriated. The fraud has been so widespread in the United States that the Justice Department recently appointed a prosecutor to go after it. People have been accused of buying a Pokémon card, a Lamborghini and other luxuries.

But Abu, population 2,952, may be the only town on earth where an entire Covid stimulus fund has vanished at the hands of an online gambler who received it through administrative error. The details of the case, and the rare attention from Japan’s national news media, have come as a shock to residents of the seaside town.

For the full story see:

Hisako Ueno and Mike Ives. “A Town’s Covid Money Was Sent to One Man in Error. He Gambled It Away.” The New York Times (Friday, May 20, 2022): A4.

(Note: bracketed date added.)

(Note: the online version of the story has the date May 19, 2022, and has the title “A Town’s Covid Money Was Sent to One Man in Error. He Gambled It All Away.”)

New York City Hurt as Wealthy Residents Move to Miami

(p. A1) When roughly 300,000 New York City residents left during the early part of the pandemic, officials described the exodus as a once-in-a-century shock to the city’s population.

Now, new data from the Internal Revenue Service shows that the residents who moved to other states by the time they filed their 2019 taxes collectively reported $21 billion in total income, substantially more than those who departed in any prior year on record. The IRS said the data captured filings received in 2020 and as late as July 2021.

Many new or returning residents have since moved in. But the total income of those who had initially left was double the average amount of those who had departed over the previous decade, a potential loss that could have long-term effects on a city that relies heavily on its wealthiest residents to support schools, law enforcement and other public services.

The sheer number of people who left in such a short period raises uncertainty about New York City’s competitiveness and economic stability. The top 1 percent of earners, who make more than $804,000 a year, contributed 41 percent of the city’s personal income taxes in 2019.

About one-third of the people who left moved from Manhattan, and had an average income of $214,300. No other large American county had a similar exodus of wealth.

Early in the pandemic, Sam Williamson, 51, a white-collar defense lawyer living on the Upper West Side of Manhattan, first relocated to Utah, then to Long Island. After a return to the city, he and (p. A19) his family permanently moved to Miami last year when his law firm opened an office there.

“I love New York City, but it’s been a challenging time,” Mr. Williamson said. “I didn’t feel like the city handled the pandemic very well.”

. . .

Gergana Ivanova, 28, a clothing designer and social media influencer, said her decision to move to Miami was less about taxes. The pandemic made the downsides of living in New York City more noticeable, she said, including the lack of space in her tiny Queens apartment and the trash piling up on the sidewalks. She felt less safe walking around when the streets were emptier.

“It didn’t feel happy and positive like it used to,” she said.

. . .

The exodus to Florida was especially robust, and not just for the retiree crowd. In 2020, New York City had a net loss of nearly 21,000 residents to Florida, IRS data showed, almost double the average annual net loss from before the pandemic.

. . .

Zak Jacoby was the general manager of a bar on the Lower East Side when the pandemic hit. Throughout 2020, his employment status fluctuated with the city’s changing indoor dining rules, a stressful period that put him on and off unemployment benefits.

Mr. Jacoby, 37, flew to Miami in January 2021 to see a friend — and decided to stay permanently after getting a job offer at a local restaurant group. If there was another virus surge, he said, the state would be less likely to shut down businesses, giving him more job security.

“My mind-set was, Florida’s more lenient on Covid, and there’s going to be less regulation,” he said.

For the full story see:

Nicole Hong and Matthew Haag. “Exodus of New York’s Wealthy Leaves Lasting Costs in Wake.” The New York Times (Tuesday, June 28, 2022): A1 & A19.

(Note: ellipses added.)

(Note: the online version of the story has the same date as the print version, and has the title “The Flight of New York City’s Wealthy Was a Once-in-a-Century Shock.” The online version of the story says that the print version has the title “An Exodus of New York’s Wealthy Has Left Lasting Costs,” but my National print version has the somewhat different title “Exodus of New York’s Wealthy Leaves Lasting Costs in Wake.”)

Lacking Government Approval During Pandemic, “State-of-the-Art Testing Machines . . . Weren’t Turned On”

(p. 12) The ethics manual of the American College of Physicians states that “the ethical imperative for physicians to provide care” overrides “the risk to the treating physician, even during epidemics.” Nevertheless, for most of human history, doctors often ran away in the face of widespread contagious disease.

. . .

When health workers stick around to treat patients, even at risk to their own lives, it is something to be celebrated, and the journalist Marie Brenner does just that in “The Desperate Hours,” an account of how workers at New York-Presbyterian, an academic health system, coped with the Covid surge in New York City beginning in the spring of 2020. The book details both medical heroism and corporate cowardice, prescient decisions and howling missteps, all against the backdrop of a swirling and mysterious pandemic that claimed the lives of more than 30,000 residents, not to mention 35 New York-Presbyterian employees.

Along the way we encounter some eye-opening anecdotes. Early on, New York City hospitals were faced with an alarming dearth of masks and a near rebellion by workers on the front lines. In response, New York-Presbyterian’s chief operating officer, Dr. Laura Forese, a pediatric orthopedic surgeon, assured staff members that “masks would not be necessary” unless workers were in direct contact with infected patients. Though she was working off mistaken C.D.C. guidelines, it was “advice and regulation that countermanded every bit of common sense understood by public health officials since the Black Plague,” Brenner writes.

. . .

Yet state-of-the-art testing machines at New York-Presbyterian weren’t turned on because the leadership was waiting for the government to approve their use. When doctors and nurses complained, the communications office attempted to throttle them and even threatened them with demotions or dismissal. It is part of what Dr. Steve Corwin, New York-Presbyterian’s chief executive, calls “a failure of imagination on our part.”

The book has its share of heroes who buck the strictures of the system to speak the truth about what was coming (or had already arrived). No one was more heroic than Dr. Nathaniel Hupert, an infectious-disease modeler at New York-Presbyterian who raised the alarm about the pandemic in February 2020 but was largely ignored.

“This is going to be historically bad, rivaling the medical consequences of 1918, but far exceeding it in terms of global financial impact,” he warned his colleagues. “If we get through this, it will be the sort of thing that we will tell our grandchildren about.” Yet when Hupert showed his projections at a planning meeting, the medical school dean told him, “I think we will be all right.”

. . .

Compounding the disaster was that little guidance was coming from executives on how to navigate the crisis, including how to potentially ration beds and ventilators (which fortunately did not come to pass). “The amount of moral damage they did to a lot of people while they get paid millions of dollars is disgusting,” a critical-care physician says bitterly.

For the full review, see:

Sandeep Jauhar. “Plagued.” The New York Times Book Review (Sunday, July 3, 2022): 12.

(Note: ellipses added.)

(Note: the online version of the review has the date June 19, 2022, and has the title “Facing Death During the Pandemic.”)

The book under review is:

Brenner, Marie. The Desperate Hours: One Hospital’s Fight to Save a City on the Pandemic’s Front Lines. New York: Flatiron Books, 2022.

“Maverick” Chinese Entrepreneur Zhou Hang Dares Criticize Zero Covid Policy

(p. B1) China’s entrepreneur class is grappling with the worst economic slump in decades as the government’s zero Covid policy has shut down cities and kept would-be customers at home. Yet they can’t seem to agree on how loudly they should complain — or even whether they should at all.

. . .

Their approach, the equivalent of an ostrich sticking its head in the sand, doesn’t make sense to Zhou Hang. Mr. Zhou, a tech entrepreneur and a venture capitalist, has questioned how his peers can pretend it’s business as usual, given the political and economic upheaval. Stop putting up with the ridiculous reality, he urged. It’s time to speak up and seek change.

Mr. Zhou is rare in China’s business community for being openly critical of the government’s zero Covid policy, which has put hundreds of millions of people under some kind of lockdowns in the past few months, costing jobs and revenues. He’s saying what many others are whispering in private but fear to say in public.

“The questions we should ask ourselves are,” he wrote in an article that was censored within an hour of posting (p. B4) but shared widely in other formats, “what caused such widespread negative sentiment across the society? Who should be responsible for this? And how can we change it?”

He said the lockdowns in Shanghai and other cities made it clear that wealth and social status meant little to a government determined to pursue its zero Covid policy. “We’re all nobodies who could be sent to the quarantine camps, and our homes could be broken into,” he wrote. “If we still choose to adapt to and put up with this, all of us will face the same destiny: trapped.”

. . .

Mr. Zhou, 49, is known as a maverick in Chinese business circles. He founded his first business in stereo systems with his brother in the mid-1990s when he was still in college. In 2010, he started Yongche, one of the first ride-hailing companies.

Unlike most Chinese bosses, he didn’t demand that his employees work overtime, and he didn’t like liquor-filled business meals. He turned down hundreds of millions of dollars in funding and refused to participate in subsidy wars because doing so didn’t make economic sense. He ended up losing out to his more aggressive competitor Didi.

He later wrote a best seller about his failure and became a partner at a venture capital firm in Beijing. In April [2022], he was named chairman of the ride-sharing company Caocao, a subsidiary of auto manufacturing giant Geely Auto Group.

A Chinese citizen with his family in Canada, Mr. Zhou said in an interview that in the past many wealthy Chinese people like him would move their families and some of their assets abroad but work in China because there were more opportunities.

Now, some of the top talent are trying to move their businesses out of the country, too. It doesn’t bode well for China’s future, he said.

“Entrepreneurs have good survivor’s instinct,” he said. “Now they’re forced to look beyond China.” He coined a term — “passive globalization” — based on his discussions with other entrepreneurs. “Many of us are starting to take such actions,” he said.

For the full story see:

Li Yuan. “A Solitary Critic on ‘Zero Covid’.” The New York Times (Saturday, June 11, 2022): B1 & B4.

(Note: ellipses, and bracketed year, added.)

(Note: the online version of the story has the date June 10, 2022 and has the title “A Chinese Entrepreneur Who Says What Others Only Think.”)