Sometimes Indigenous People Know More Than Credentialed Scientists

(p. D4) As a group of European botanists prepared to travel across Borneo by motorboat and four-wheel-drive vehicles, they heard about a species of palm with an extremely rare quirk.

It flowers underground.

The palm, Pinanga subterranea, is one of 74 plants that scientists from the Royal Botanic Gardens, Kew, in London named as new to science last year, thrilling some in the botany world. The botanists who went plant-hunting in Southeast Asia six years ago were not expecting to find it.

But the plant is not hard to find: It grows abundantly on Borneo, the third-largest island in the world, which includes parts of Indonesia and Malaysia.

. . .

. . ., the “discovery” of Pinanga subterranea is an example of conventional science catching up with Indigenous knowledge.

“We have described this as new to science,” said William J. Baker, the most senior scientist on the trip. “But the preexisting knowledge about this palm is layered, and was already there before we even got anywhere near it.”

Over the past 30 years, non-Indigenous scientists have turned more to Indigenous knowledge to expand or test their research, with varying degrees of sensitivity.

. . .

There have been a number of collaborative studies that credit Indigenous communities with having generations of wisdom on topics that include shellfish productivity, grizzly bear management and raptor behavior. In some cases the communities lead or participate in the research.

For the full story see:

Mike Ives and Hasya Nindita. “‘New to Science’ Plant Wasn’t Such a Secret.” The New York Times (Tuesday, January 30, 2024): D4.

(Note: ellipses added.)

(Note: the online version of the story has the date Jan. 20, 2024, and has the title “A Plant That Flowers Underground Is New to Science, but Not to Borneo.”)

“Fiennes Is Superb” as “Calmly Eccentric Self-Taught Scholar”

(p. A13) Every now and then a film comes along—not a great one, necessarily—that makes you deeply glad. It’s how I feel about “The Dig.”

. . .

The dig in question has come to be called Sutton Hoo, after its site on the banks of a tidal river in Suffolk. The film, directed by Simon Stone and adapted by Moira Buffini from a John Preston novel about the discovery, plunges us into the adventure by following an unassuming gent named Basil Brown (Ralph Fiennes) as he bicycles his way to the fairly imposing house of Edith Pretty (Carey Mulligan), a widow eager to investigate a mysterious group of mounds on her property. The project calls for an archaeologist—not Indiana Jones, necessarily, but someone with more extensive training than Basil, who was, in real life, the man who made the discovery, and who describes himself here with with laconic pride as a lifelong excavator. Yet the nation is preparing for war, no archaeologists are available and Basil will have to do.

Thus does “The Dig” deftly address issues of class—Basil knows more about the history and texture of Suffolk’s soil than any credentialed expert a museum might have sent—while giving us a prime example of an archetype dear to English films, the calmly eccentric self-taught scholar (who of course smokes a pipe). Mr. Fiennes is superb in the role—you’ll be glad to watch him digging away with his shovel, and you’ll be thrilled, as I was, when, after digging for a good while, he shows up at Edith’s door and says, his voice quivering with emotion, “I think you’d better come and see.” (The emotional spectrum of the cinematography, by Mike Eley, ranges from solemn to ecstatic.)

For the full review see:

Joe Morgenstern. “Unearthing a Glittering Tale.” The Wall Street Journal (Friday, Jan. 29, 2021 [sic]): A13.

(Note: ellipsis added.)

(Note: the online version of the review has the date January 28, 2021 [sic], and has the title “‘The Dig’: Unearthing a Glittering Tale.”)

Successes of Thiel’s Entrepreneurial Anti-College Fellowships Undermine Veneration of Higher Ed

Gary Becker won the Nobel Prize in part for his work as a founder of the study of the economics of human capital. One common finding of the field is that investment in higher education has a high rate of return. So Becker was puzzled when his own grandson pondered skipping college in order to directly become a technology entrepreneur.

I speculate that information technology will make it increasingly easy for autodidacts to learn on their own what they need to know, whenever they need to know it. I further speculate that formal education, especially formal higher education, will wither into irrelevance, just as the Post Office has withered in the face of email and Amazon.

(p. B4) Peter Thiel is trying harder than ever to get young people to skip college.

Since 2010, Thiel, an early Facebook investor and a founder of PayPal Holdings, has offered to pay students $100,000 to drop out of school to start companies or nonprofits.

. . .

Some big successes include Vitalik Buterin, co-founder of Ethereum, the blockchain network; Laura Deming, a key figure in venture investing in aging and longevity; Austin Russell, who runs self-driving technologies company Luminar Technologies; and Paul Gu, co-founder of consumer lending company Upstart.

When he began his fellowship, Thiel, a vocal libertarian who was an active supporter of Donald Trump in 2016, was disenchanted with leading colleges and convinced they weren’t best suited for many young people.

His aim, at least in part, was to undermine the popular view that college was necessary for all students, and that top universities should be accorded prestige and veneration.

Since then, public opinion has shifted toward his perspective. More Americans are rethinking the value of a college education. At the same time, America’s elite universities have come under fire for their handling of a surge in antisemitism and for maintaining what critics call a double standard regarding free speech.

For the full story see:

Gregory Zuckerman. “Thiel’s Offer to Skip College Draws Many.” The Wall Street Journal (Monday, Feb. 26, 2024): B4.

(Note: ellipsis added.)

(Note: the online version of the story has the date February 24, 2024, and has the title “Peter Thiel’s $100,000 Offer to Skip College Is More Popular Than Ever.”)

Becker is best known for:

Becker, Gary S. Human Capital: A Theoretical and Empirical Analysis; with Special Reference to Education. 3rd ed. New York: Columbia University Press, 1993.

Black Physician Wants to “Play Fair” and Be Judged on Merit

(p. A17) Do I deserve to jump the line? If I say yes, I may play a leading role in ending the scourge of atherosclerosis—also known as hardening of the arteries. If I play fair, I may lose the opportunity to save people around the world from heart attacks and strokes. I’m angry at the National Institutes of Health for putting me in this position. I’m even angrier it has done so in the name of racial equity.

My quandary comes down to whether I should “check the box” on an upcoming NIH grant application attesting to my recent African heritage. Since at least 2015, the NIH has asserted its belief in the intrinsic superiority of racially diverse research teams, all but stating that such diversity influences funding decisions. My family’s origins qualify me under the federal definition of African-American. Yet I feel it’s immoral and narcissistic to use race to gain an advantage over other applicants. All that should matter is the merit of my application and the body of my work, which is generally accepted as foundational in atherosclerosis research.

. . .

If I refuse to identify myself as African-American, our application is more likely to lose on “diversity” grounds. It’s a double wrong. Not only is the system rigged based on nonscientific—and possibly illegal—criteria; it encourages me to join in the rigging.

Truth be told, I made my decision years ago. When my study team files our application, it won’t note my West African origins. If we don’t get the grant, so be it. I refuse to engage in a moral wrong in pursuit of a moral good—even one as important as saving lives from the leading killer on earth. My father, who struggled against racism to achieve so much on the merits of his own work, would never forgive me for “checking the box” to grab a race-based advantage.

And no matter what happens, I can never forgive the National Institutes of Health for reinjecting racism into medical research.

For the full commentary see:

Kevin Jon Williams. “Why I’m Saying No to NIH’s Racial Preferences.” The Wall Street Journal (Thursday, March 28, 2024): A17.

(Note: ellipsis added.)

(Note: the online version of the commentary has the date March 27, 2024, and has the same title as the print version.)

So-Called “Progressives” Block Progress Toward School Choice

(p. A15) I was wrong to think that Democrats would support school choice to help their constituents out of poverty. Although polling consistently shows that a majority of minority parents want school choice, progressive politicians consistently oppose all such programs.

To understand why, consider who’s funding their campaigns: teachers unions. For unions, choice means competition, and urban public schools with low proficiency ratings can’t compete. Unions know the only way to keep their political power is to keep children trapped in failing schools. Give parents access to other educational options, and they’ll ditch the schools that take them for granted.

. . .

I have discussed school choice with Mr. Trump, and I’m encouraged by what he said. I’m likewise impressed by his actions to advance the cause in real time—namely, by endorsing several of the pro-school choice Republicans in Texas’s legislative primaries. If Mr. Trump uses his bully pulpit to build support for school choice across the country, as he did in Texas, I believe he’ll help improve the lives of many generations of Americans.

I’ve never given financial support to Mr. Trump’s campaign, and I don’t plan to. But on the issue I care about most deeply, the stakes are high.  . . .  . . . the choice is clear.

For the full commentary see:

Jeff Yass. “Trump Is Best for School Choice, Even if I Won’t Donate to Him.” The Wall Street Journal (Tuesday, April 9, 2024): A15.

(Note: ellipses added.)

(Note: the online version of the commentary has the date April 8, 2024, and has the title “Trump Is Best for School Choice, Even if I Won’t Donate to His Campaign.”)

Babies’ Curiosity Leads Them to Prefer Persons Who Inform

(p. C2) . . . Katarina Begus of Birkbeck, University of London and her colleagues . . . started out exploring the origins of curiosity. When grown-ups think that they are about to learn something new, their brains exhibit a pattern of activity called a theta wave. The researchers fitted out 45 11-month-old babies with little caps covered with electrodes to record brain activity. The researchers wanted to see if the babies would also produce theta waves when they thought that they might learn something new.

The babies saw two very similar-looking people interact with a familiar toy like a rubber duck. One experimenter pointed at the toy and said, “That’s a duck.” The other just pointed at the object and instead of naming it made a noise: She said “oooh” in an uninformative way.

Then the babies saw one of the experimenters pick up an unfamiliar gadget. You would expect that the person who told you the name of the duck could also tell you about this new thing. And, sure enough, when the babies saw the informative experimenter, their brains produced theta waves, as if they expected to learn something. On the other hand, you might expect that the experimenter who didn’t tell you anything about the duck would also be unlikely to help you learn more about the new object. Indeed, the babies didn’t produce theta waves when they saw this uninformative person.

. . .

Babies leap at the chance to learn something new—and can figure out who is likely to teach them. The babies did prefer the person in their own group, but that may have reflected curiosity, not bias. They thought that someone who spoke the same language could tell them the most about the world around them.

For the full commentary see:

Alison Gopnik. “Mind & Matter; Babies Show a Clear Bias—To Learn New Things.” The Wall Street Journal (Saturday, Oct. 29, 2016 [sic]): C2.

(Note: ellipses added.)

(Note: the online version of the commentary was updated Oct. 26, 2016 [sic], and has the same title as the print version.)

Begus’s co-authored academic paper is:

Begus, Katarina, Teodora Gliga, and Victoria Southgate. “Infants’ Preferences for Native Speakers Are Associated with an Expectation of Information.” Proceedings of the National Academy of Sciences 113, no. 44 (2016): 12397-402.

In “An Entrenched Echo Chamber” the Highly Credentialed Slow Progress Toward an Alzheimer’s Cure

Centralized research funding (often centralized by government agencies) reduces the pluralism of ideas and methods that often lead to breakthrough innovations. The story of Alzheimer’s research, quoted below, is a dramatic case-in-point.

A secondary related lesson from the story quoted below is that Dr. Thambisetty, one of the outsiders struggling to make a difference, is trying to evade the enormous costs of mandated phase 3 clinical trials, by only investigating drugs that already have been approved by the FDA for use against other conditions. With his severely limited funding, and the huge costs of mandated phase 3 clinical trials, this may be a shrewd strategy for Thambisetty, but notice that by following it, he will never explore all the as-yet-unapproved chemicals that might include the best magic bullet against Alzheimer’s.)

(p. A25) What if a preposterous failed treatment for Covid-19 — the arthritis drug hydroxychloroquine — could successfully treat another dreaded disease, Alzheimer’s?

Dr. Madhav Thambisetty, a neurologist at the National Institute on Aging, thinks the drug’s suppression of inflammation, commonly associated with neurodegenerative disorders, might provide surprising benefits for dementia.

It’s an intriguing idea. Unfortunately, we won’t know for quite a while, if ever, whether Dr. Thambisetty is right. That’s because unconventional ideas that do not offer fealty to the dominant approach to study and treat Alzheimer’s — what’s known as the amyloid hypothesis — often find themselves starved for funds and scientific mind share.

Such shortsighted rigidity may have slowed progress toward a cure — a tragedy for a disease projected to affect more than 11 million people in the United States by 2040.

. . .

. . ., in 2006, an animal experiment published in the journal Nature identified a specific type of amyloid protein as the first substance found in brain tissue to directly cause symptoms associated with Alzheimer’s. Top scientists called it a breakthrough that provided a key target for treatments. The paper became one of the most cited in the field, and funds to explore similar proteins skyrocketed.

. . .

In 2022, my investigation in Science showed evidence that the famous 2006 experiment that helped push forward the amyloid hypothesis used falsified data. On June 24 [2024], after most of its authors conceded technical images were doctored, the paper was finally retracted.

. . .

In reporting for my forthcoming book about the disturbing state of play in Alzheimer’s research, I’ve spoken to many scientists pursuing alternatives. Dr. Thambisetty, for example, compares brain tissues from people who died in their 30s or 40s with and without genetic risk factors for Alzheimer’s. He then compares these findings to tissues from deceased Alzheimer’s patients and people who didn’t have the disease. Where changes overlap, drug targets might emerge. Rather than develop new drugs through lab and animal testing, followed by clinical trials that cost vast sums — a process that can take decades — he examines treatments already approved as reasonably safe and effective for other conditions. Patent protections have lapsed for many, making them inexpensive.

Experiments have also begun to test the weight-loss drug semaglutide (sold as Wegovy, among other brands). Researchers hope that results due in 2026 will show that its anti-inflammatory effects — like Dr. Thambisetty’s idea about hydroxychloroquine — slow cognitive decline.

Ruth Itzhaki, a research scientist at the University of Oxford, stirred curiosity in the 1990s when she shared evidence tying Alzheimer’s to herpesvirus — a scourge spread by oral or genital contact and often resulting in painful infections. For years, powerful promoters of the amyloid hypothesis ignored or dismissed the infection hypothesis for Alzheimer’s, effectively rendering it invisible, Dr. Itzhaki said with exasperation. Research suggests that viruses may hide undetected in organs, including the brain, for years, causing symptoms divergent from the original infection.

. . .

Sometimes a disease stems from a single clear-cut origin, such as genetic mutations that cause deadly sickle cell disease. “But very few diseases of aging have just one cause. It’s just not logical,” said Dr. Matthew Schrag, a neurologist at Vanderbilt University Medical Center. Working independently of his university, he discovered the 2006 research image manipulations.

. . .

“There is an entrenched echo chamber that involves a lot of big names,” Dr. Schrag said. “It’s time for the field to move on.”

For the full commentary see:

Charles Piller. “All the Alzheimer’s Research We Didn’t Do.” The New York Times (Friday, July 12, 2024): A25.

(Note: ellipses, and bracketed year, added.)

(Note: the online version of the commentary has the date July 7, 2024, and has the same title as the print version. Where there are a couple of small differences in wording, the passages quoted above follow the online version.)

Piller’s paper in Science, mentioned above, is:

Piller, Charles. “Blots on a Field?” Science 377, no. 6604 (July 2022): 358-63.

Piller’s commentary is related to his forthcoming book:

Piller, Charles. Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s. New York: Atria/One Signal Publishers, Forthcoming on February 4, 2025.

“Funny, Obsessed Weirdos . . . Taking Children’s Entertainment . . . Seriously”

(p. C4) . . . to everyone other than Muppet obsessives, Henson the artist is still a bit shadowy. Good news: Now we have “Jim Henson Idea Man” (on Disney+), a tribute to the artist and a treasure trove of archival footage and interviews about his work and life.  . . .

The film, directed by Ron Howard, starts with Henson and two of his Muppet friends, Fozzie Bear and Kermit the Frog — Henson’s alter ego — being interviewed on TV by none other than Orson Welles.

. . .

. . . what struck me especially was that Howard has made a movie that every young artist should watch (and older ones, too), whether they’re making puppets, paintings, music, movies or anything that requires creative labor.

That’s because the film shows that Henson’s work was rooted in an unquenchable drive for exploration. One interviewee notes that he was lured into working on “Sesame Street” by the promise that he could make the kind of short experimental films he loved — and suddenly I realized that my taste for unhinged abstraction in film had been partly shaped when I was 4 and plopped in front of PBS.

. . .

The immense delight in “Jim Henson Idea Man” comes with simply watching funny, obsessed weirdos like Henson and his friends doing something nobody else was doing, something few people do anymore: taking children’s entertainment (and later adult entertainment) seriously as craft. I’ve heard naysayers argue that it’s silly to ask children’s movies to be any good, since they’re just for kids. But Henson knew better: Every opportunity to make something was a chance to explore with the audience. There’s a reason, then, that his work lasts.

For the full review see:

Alissa Wilkinson. “CRITIC’S NOTEBOOK; Took Kid Stuff Seriously.” The New York Times (Wednesday, June 5, 2024): C4.

(Note: ellipses added.)

(Note: the online version of the review has the dated May 31, 2024, and has the title “CRITIC’S NOTEBOOK; ‘Jim Henson Idea Man’: In a Joyful Weirdo, Lessons for Young Artists.”)

“Extended School Closures Did Not Significantly Stop the Spread of Covid, While the Academic Harms for Children Have Been Large and Long-Lasting”

(p. A13) Four years ago this month, schools nationwide began to shut down, igniting one of the most polarizing and partisan debates of the pandemic.

Some schools, often in Republican-led states and rural areas, reopened by fall 2020. Others, typically in large cities and states led by Democrats, would not fully reopen for another year.

A variety of data — about children’s academic outcomes and about the spread of Covid-19 — has accumulated in the time since. Today, there is broad acknowledgment among many public health and education experts that extended school closures did not significantly stop the spread of Covid, while the academic harms for children have been large and long-lasting.

For the full story see:

Sarah Mervosh, Claire Cain Miller and Francesca Paris. “Pandemic School Closures Came at a Steep Cost to Students, Data Shows.” The New York Times (Friday, March 29, 2024): A13.

(Note: the online version of the story was updated March 19, 2024, and has the title “What the Data Says About Pandemic School Closures, Four Years Later.”)

Jerry Seinfeld Knows “the Extreme Left and P.C. Crap” Hampers Comedy

(p. C1) Since the attacks of Oct. 7 [2023] in Israel, and through their bloody and volatile aftermath in Gaza, Mr. Seinfeld, 70, has emerged as a strikingly public voice against antisemitism and in support of Jews in Israel and the United States, edging warily toward a more forward-facing advocacy role than he ever seemed to seek across his decades of fame.

He has shared reflections about life on a kibbutz in his teens, and in December traveled to Tel Aviv to meet with hostages’ families, soberly recounting afterward the missile attack that greeted him during the trip.

He has participated, to a point, in the kind of celebrity activism with which few associate him — letter-signing campaigns, earnest messages on social media — answering simply recently when asked about the motivation for his visit to Israel: “I’m Jewish.”

And as some American cities and college campuses simmer with conflict over the Middle East crisis and Israel’s military response, Mr. Seinfeld has faced a measure of public scorn that he has rarely courted as a breakfast-obsessed comedian, intensified by the more vocal advocacy of his wife, Jessica, a cookbook author.

. . .

(p. C4) Since “Seinfeld,” he has spoken most expansively about the art of comedy itself, framing it as a morally neutral pursuit whose highest aim is to make people laugh. (Mr. Seinfeld recently made headlines for suggesting in an interview with The New Yorker that “the extreme left and P.C. crap” had hampered comedy.)

For the full story see:

Matt Flegenheimer and Marc Tracy. “Jerry Seinfeld Is Clearly No Longer About Nothing.” The New York Times (Monday, May 6, 2024): C1 & C4.

(Note: ellipsis, and bracketed year, added.)

(Note: the online version of the story has the date May 4, 2024, and has the title “Jerry Seinfeld Can No Longer Be About Nothing.”)

Tax Universities to Offset Their Negative Externalities?

(p. A11) What can we do about the corruption of American higher education? Milton Friedman had an idea 20 years ago: Tax the schools rather than subsidize them. That reflected a change of heart. In “Capitalism and Freedom” (1960), he argued that college education had enough “positive externalities” to justify subsidies. But when I was researching a book in 2003, I emailed him (then 91) and asked if he still believed that.

He replied: “I have not changed my view that higher education has some positive externality, but I have become much more aware that it also has negative externalities. I am much more dubious than I was . . . that there is any justification at all for government subsidy of higher education. The spread of PC”—political correctness—“would seem to be a very strong negative externality, and certainly the 1960s student demonstrations were negative externalities. . . . A full analysis along those lines might lead you to conclude that higher education should be taxed to offset its negative externalities.”

For the full commentary, see:

Richard Vedder. “Harvard Should Pay Its Fair Share.” The Wall Street Journal (Saturday, Dec. 23, 2023): A11.

(Note: ellipses in original.)

(Note: the online version of the commentary has the date December 22, 2023, and has the same title as the print version.)

Friedman’s book mentioned above is:

Friedman, Milton. Capitalism and Freedom. Chicago: The University of Chicago Press, 1962.