Dogs Can Alert Owners to Epileptic or Diabetic Emergencies

(p. B1) Rosebud is a service dog trained at a nonprofit called Canine Partners for Life in Cochraneville, Pa. The dog can detect when Ms. Vible will have a seizure about 15 minutes before it happens. She lets Ms. Vible know with a whine or a bark and then lies down with her owner until the seizure is over.

Seizure-alert dogs are part of a growing class of service animals that can detect warning signs of epileptic seizures and diabetic emergencies and identify other medical conditions. Demand has surged, according to trainers and training centers—some of which now have long wait lists—as recent scientific studies have started to confirm the dogs’ efficacy in helping their owners.

. . .

Their acute sense of smell helps the dogs detect low and high blood-sugar levels and epileptic seizures before they happen. Researchers haven’t yet identified the specific compounds that the dogs are smelling. But once the dogs recognize the smell, they are trained to respond with a specific action such as barking or pawing at their owners. Depending on the owner’s state and the animal’s training, some dogs also might alert another adult, bring a juice box or press a button that sends a phone text to a caregiver.

The University of Bristol in England this year produced a study of dogs’ ability to detect hypoglycemia, which occurs when a diabetic’s blood sugar drops dangerously. If left untreated, this can lead to unconsciousness or death. In assessing the effectiveness of 27 glycemia-alert dogs, the Bristol study found that the dogs alerted their owners to 83% of hypoglycemic episodes in more than 4,000 hypo- and hyperglycemic episodes.

The findings of another study released this year showed promise for people suffering from epilepsy. Researchers from the University of Rennes in Normandy, France, presented dogs with samples of breath and sweat odors obtained from epileptic patients having seizures, not having seizures and exercising (to determine whether the dogs were just detecting sweat). All of the dogs succeeded in identifying the epileptic-seizure-odor sample, and the dogs spent about 23 seconds investigating the seizure smell, compared with about five seconds spent on the other samples.

The lead researcher of the study, Amelie Catala, a Ph.D. candidate at the University of Rennes, says the research could help in the development of electronic noses, devices that can detect and analyze odors and flavors.

“If there is an organic compound related to these diseases that we can detect and identify, it could help develop electronic noses,” she says.

Medical-alert dogs are being trained by for-profit and nonprofit centers, by individual trainers and at times by individual pet owners themselves. In addition to those skills already mentioned, some have been trained to warn patients about abnormal heart rhythms, and to detect allergens. Dogs also have been trained to help identify certain cancers in laboratory settings.

For the full story, see:

Aili McConnon. “Dogs That Can Read Warning Signs Progress Before Explosion.” The Wall Street Journal (Monday, Sept. 16, 2019 [sic]): R9.

(Note: ellipsis added.)

(Note: the online version of the story has the date Sept. 12, 2019 [sic], and has the title “A Growing Role for Medical-Alert Dogs.” The last four paragraphs quoted above appear in the online, but not in the print, version of the article.)

The University of Bristol academic paper mentioned above is:

Rooney, Nicola J., Claire M. Guest, Lydia C. M. Swanson, and Steve V. Morant. “How Effective Are Trained Dogs at Alerting Their Owners to Changes in Blood Glycaemic Levels?: Variations in Performance of Glycaemia Alert Dogs.” PLOS ONE 14, no. 1 (2019): e0210092.

The University of Rennes academic paper mentioned above is:

Catala, Amélie, Marine Grandgeorge, Jean-Luc Schaff, Hugo Cousillas, Martine Hausberger, and Jennifer Cattet. “Dogs Demonstrate the Existence of an Epileptic Seizure Odour in Humans.” Scientific Reports 9, no. 1 (2019): article #4103.

Shark Tank Shows Capitalism as a “Bootstrap Meritocracy”

(p. 24) . . . my favorite TV show is “Shark Tank.”  . . .  The premise of the tank is that small-business owners get an audience with investors — the “sharks,” a crew of millionaires and billionaires that includes Mark Cuban, Daymond John and Lori Greiner, the “queen of QVC” — in the hope of provoking a bidding war for a stake in the company. Sometimes the sharks dismiss the ideas outright, and they often do so cruelly, but in a satisfying, detailed way. You start to feel as if you could write your own business plan after watching a few episodes.

. . .

(p. 25) The show dramatizes a romantic vision of our economy, depicting it as a bootstrap meritocracy.

. . .

Part of the show’s appeal is that it’s an equal-opportunity forum — you don’t have to know a Silicon Valley V.C. or even a banker to get your audience with the sharks.

. . .

I was so politically assertive as a kid because I wanted someone to respect my opinion, to value me. I wanted to be taken seriously. I think most kids feel this way, dismissed outright for being small. In the tank, no one is dismissed — the sharks start every segment with furrowed brows, ready to take notes and hear out pitches, no matter how preposterous. They begin the process with a clean slate every time. Somewhere deep down, I want all these deals to work, I want the enthusiasm that sharks feel to be genuine and I want the contestants to walk away with business plans ready to be set into motion. Even if “Shark Tank” is propaganda — the selling and marketing of the American dream — the fantasy feels real.

For the full commentary, see:

Jaime Lowe. “Letter of Recommendation: ‘Shark Tank’.” The New York Times Magazine (Sunday, October 1, 2017 [sic]): 24-25.

(Note: ellipses added.)

(Note: the online version of the commentary has the date Sept. 28, 2017 [sic], and has the same title as the print version.)

SpaceX Embraces Fast Failures as the Best Path to Fast Fixes

(p. B1) SpaceX’s Starship spacecraft pulled off an extended flight through space on its third test mission, marking major progress for a vehicle that could one day transport astronauts to the moon and beyond.

Shortly after launching the nearly 400-foot-tall rocket Thursday [March 14, 2024], SpaceX successfully separated the booster from the spacecraft, which proceeded to fly for around an hour before it was lost while re-entering Earth’s atmosphere, according to a company livestream.

The mission advanced much farther than the company’s previous two Starship test flights. It was a milestone for a vehicle that is a centerpiece of SpaceX’s commercial ambitions, NASA’s space exploration plans, and company founder Elon Musk’s goal of one day sending humans to Mars.

. . .

(p. B4) Current and former SpaceX leaders have said the company embraces failing fast to try to rapidly identify fixes and improve. The company took 63 corrective actions to address issues that emerged during the initial launch, and an additional 17 following the second, according to the FAA.

For the full story, see:

Micah Maidenberg. “SpaceX Starship’s Third Test Mission Marks Major Progress Before Explosion.” The Wall Street Journal (Friday, March 15, 2024): B1 & B4.

(Note: ellipsis, and bracketed date, added.)

(Note: the online version of the story was updated March 14, 2024, and has the title “SpaceX’s Starship Makes Major Progress in Third Flight Test.”)

Allowing the Sale of Hearing Aids Over-the-Counter (O.T.C.) Results in “Increased Innovation and Lower Prices”

(p. D3) A year ago, the Food and Drug Administration announced new regulations allowing the sale of over-the-counter hearing aids and setting standards for their safety and effectiveness.

. . .

Some background: In 2020, the influential Lancet Commission on Dementia Prevention, Intervention and Care identified hearing loss as the greatest potentially modifiable risk factor for dementia.

Previous studies had demonstrated a link between hearing loss and cognitive decline, said Dr. Frank Lin, an otolaryngologist and epidemiologist at Johns Hopkins and lead author of the new research.

“What remained unanswered was, If we treat hearing loss, does it actually reduce cognitive loss?” he said. The ACHIEVE study (for Aging and Cognitive Health Evaluation in Elders) showed that, at least for a particular group of older adults, it could.

. . .

A small study recently published in JAMA Otolaryngology found that patients who were given a commercially available, self-fitting hearing aid in a clinical trial could, after six weeks, hear as well as patients fitted with the same device by audiologists.

. . .

The United States is the first country to develop a regulated O.T.C. hearing aid market, and “the tech companies and the retailers are still experimenting,” Dr. Lin pointed out. He predicts increased innovation and lower prices ahead.

For the full commentary, see:

Paula Span. “THE NEW OLD AGE; A Challenging Over-the-Counter Market for Hearing Aids.” The New York Times (Tuesday, October 31, 2023): D3.

(Note: ellipses added.)

(Note: the online version of the commentary has the date Oct. 30, 2023, and has the title “THE NEW OLD AGE; Hearing Aids Are More Affordable, and Perhaps More Needed, Than Ever.”)

The “small study” mentioned above is:

De Sousa, Karina C., Vinaya Manchaiah, David R. Moore, Marien A. Graham, and De Wet Swanepoel. “Effectiveness of an over-the-Counter Self-Fitting Hearing Aid Compared with an Audiologist-Fitted Hearing Aid: A Randomized Clinical Trial.” JAMA Otolaryngology–Head & Neck Surgery 149, no. 6 (2023): 522-30.

Musk Calls German Anti-Electric-Vehicle Ecoactivists “Dumber Than a Doorstop”

(p. B1) GRÜNHEIDE, Germany—When Tesla opened its first full-scale European factory in this sleepy community outside of Berlin, Elon Musk was feted as a hero, the chancellor gave a speech and workers cheered the rollout of new Model Ys.

On Wednesday [March 13, 2024], almost two years to the day later, Musk was back, this time to cheer up workers after an act of sabotage by suspected eco-activists shut down the plant for more than a week.

. . .

Tesla didn’t respond to requests for comment on the various incidents. In a post on his X social-media platform, Musk has called the eco-activists “dumber than a doorstop” for their criticism of electric vehicles.

As the plant’s managers and workers gathered in a tent on the factory grounds for a “team huddle” on Wednesday, Musk could be seen carrying his son. Hoisting the boy onto his shoulders amid calls of “Elon, Elon,” he shouted back: “They can’t stop us!” and “Ich liebe Dich!”—German for “I love you.”

As he left, reporters asked him whether he was still committed to expanding the plant and producing vehicles in Germany.

“Yes, absolutely,” he said. “Germany rocks!”

For the full story, see:

William Boston. “Tesla Faces Blowback in Germany.” The Wall Street Journal (Friday, March 15, 2024): B1-B2.

(Note: ellipses, and bracketed date, added.)

(Note: the online version of the story has the date March 14, 2024, and has the title “Elon Musk’s Plans to Conquer Europe Collide With Germany’s Culture Wars.”)

Researchers and Entrepreneurs Experiment with Once-Taboo Geoengineering Projects to Reverse Global Warming

(p. A3) Dumping chemicals in the ocean? Spraying saltwater into clouds? Injecting reflective particles into the sky? . . .

These geoengineering approaches were once considered taboo by scientists and regulators who feared that tinkering with the environment could have unintended consequences, but now researchers are receiving taxpayer funds and private investments to get out of the lab and test these methods outdoors.

. . .

In Israel, a startup called Stardust Solutions has begun testing a system to disperse a cloud of tiny reflective particles about 60,000 feet in altitude, reflecting sunlight away from Earth to cool the atmosphere in a concept known as solar radiation management, or SRM. Yanai Yedvab, Stardust chief executive and a former deputy chief scientist at the Israel Atomic Energy Commission, wouldn’t disclose the composition of the proprietary particles.

Yedvab said Stardust has raised $15 million from two investors and has conducted low-level aerial tests using white smoke to simulate the particles’ path in the atmosphere. After the company completes indoor safety testing, it intends to conduct a limited outdoor test of the dispersion technology, monitoring devices and particles in the next few months, Yedvab said.

. . .

Experiments aimed at cooling the atmosphere by reflecting sunlight away from Earth are an attempt to mimic what happens when a volcano erupts. In 1991, Mount Pinatubo, an active volcano in the Philippines, spewed sulfur and ash into the upper atmosphere, lowering the Earth’s temperature by .5 degrees Celsius (.9 degrees Fahrenheit) for an entire year.

For the full story, see:

Eric Niiler. “New Experiments Aim to Cool Planet.” The Wall Street Journal (Thursday, February 15, 2024): A3.

(Note: ellipses added.)

(Note: the online version of the story has the date February 14, 2024, and has the title “Scientists Resort to Once-Unthinkable Solutions to Cool the Planet.” The online version says that the title of the print version was also “Scientists Resort to Once-Unthinkable Solutions to Cool the Planet.” But my print version has the title “New Experiments Aim to Cool Planet.”)

Isaacson Reprises His Themes of “Science, Genius, Experiment, Code, Thinking Different” in Book on CRISPR

(p. 12) The landmark research that brought Doudna and Charpentier to the pinnacle of global acclaim has the potential to control future pandemics — either by outwitting the next viral plague through better screening and treatment or by engineering human beings with better disease resistance programmed into their cells. The technique of gene editing that they patented, which goes by the unwieldy acronym of CRISPR-Cas9, makes it possible to selectively snip and alter bits of DNA as though they were so many hems to take up or waistbands to let out. The method is based on defenses pioneered by bacteria in their ages-old battle against viruses.

. . .

The CRISPR history holds obvious appeal for Walter Isaacson, a biographer of Albert Einstein, Benjamin Franklin, Steve Jobs and Leonardo da Vinci. In “The Code Breaker” he reprises several of his previous themes — science, genius, experiment, code, thinking different — and devotes a full length book to a female subject for the first time.

. . .

Isaacson keeps a firm, experienced hand on the scientific explanations, which he mastered through extensive readings and interviews, all of which are footnoted.

For the full review, see:

Dava Sobel. “Deus Ex Machina.” The New York Times Book Review (Sunday, March 21, 2021 [sic]): 12.

(Note: ellipses added.)

(Note: the online version of the review has the date March 8, 2021 [sic], and has the title “A Biography of the Woman Who Will Re-Engineer Humans.”)

The book under review is:

Isaacson, Walter. The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race. New York: Simon & Schuster, 2021.

Federal and State Regulatory Thicket Thwarts “Permitting, Siting, Construction and Operation” of New Energy Infrastructure and Technology

(p. C5) Environmentalists have long argued that tackling climate change will require regulations to discourage fossil-fuel use, such as a carbon tax or a cap-and-trade program. In reality, there is no plausible path to a low-carbon economy without a serious deregulatory program. Today’s thicket of environmental regulation at the federal and state levels thwarts permitting, siting, construction and operation of virtually every class of new infrastructure and technology. There are simply too many veto points and opportunities for obstruction, at too many procedural and jurisdictional levels, to conceivably embark on a rapid mission to remake the nation’s energy economy.

. . .

The U.S. can no longer continue to neglect its compounding infrastructure and clean-energy needs. We aren’t going to regulate our way to a thriving low-carbon economy and a more stable climate. America needs to get back to building again.

For the full commentary, see:

Ted Nordhaus. “For a Clean-Energy Future, We Need Deregulation.” The Wall Street Journal (Saturday, February 19, 2022 [sic]): C5.

(Note: ellipsis added.)

(Note: the online version of the commentary has the date February 17, 2022 [sic], and has the same title as the print version.)

“Momentum Around Solar Geoengineering Is Building Fast”

(p. A19) A few years ago, the idea of deliberately blocking the sun to combat climate change was taboo for scientists. But a lot can change in a short time.

As the disastrous effects of climate change mount, Congress has asked federal scientists for a research plan, private money is flowing and rogue start-ups are attempting experiments — all signs that momentum around solar geoengineering is building fast. The most discussed approach involves spraying tiny particles into the stratosphere to reflect sunlight and cool the planet. Other proposals include injecting sea salt into clouds to increase their reflectivity or using giant space parasols to block the sun.

It might all sound like dystopian science fiction, but some techno-futurists, like OpenAI’s chief executive, Sam Altman, are already normalizing it: “We’re going to have to do something dramatic with climate like geoengineering as a Band-Aid, as a stopgap,” he said in January [2024] at the World Economic Forum in Davos.

No one fully understands the risks of these technologies — which could include calamitous disruptions in weather — or how significant the benefits could be. I’m increasingly convinced that we should do more research on solar geoengineering.

. . .

. . . science is fallible precisely because it is a practice, a cooperative human activity. And as the moral philosopher Alasdair MacIntyre reminds us, engaging in a practice well requires exercising its virtues — which for science include transparency, honesty, humility, skepticism and collaboration.

For the full commentary, see:

Jeremy Freeman. “Let’s Find Out if This Can Cool the Planet.” The New York Times (Tuesday, March 19, 2024): A19.

(Note: ellipses, and bracketed year, added.)

(Note: the online version of the commentary has the date March 17, 2024, and has the title “The Best Way to Find Out if We Can Cool the Planet.”)

Texas Is “One State” Whose “Streamlined Permitting Process Allows Wind, Solar and Battery Projects to Get Built and Connected”

(p. A1) Something unusual is happening in America. Demand for electricity, which has stayed largely flat for two decades, has begun to surge.

Over the past year, electric utilities have nearly doubled their forecasts of how much additional power they’ll need by 2028 as they confront an unexpected explosion in the number of data centers, an abrupt resurgence in manufacturing driven by new federal laws, and millions of electric vehicles being plugged in.

Many power companies were already struggling to keep the lights on, especially during extreme weather, and say the strain on grids will only increase. Peak demand in the summer is projected to grow by 38,000 megawatts nationwide in the next five years, according to an analysis by the consulting firm Grid Strategies, which is like adding another California to the grid.

“The numbers we’re seeing are pretty crazy,” said Daniel Brooks, vice president of integrated grid and energy systems at the Electric Power Research Institute, a nonprofit organization.

In an ironic twist, the swelling appetite for more electricity, driven not only by electric cars but also by battery and solar factories and other aspects of the clean-energy transition, could also jeopardize the country’s plans to fight climate change.

To meet spiking demand, utilities in states like Georgia, North Carolina, South Carolina, Tennessee and Virginia are proposing to build dozens of power plants over the next 15 years that would burn natural gas. In Kansas, one utility has postponed the retirement of a coal plant to help power a giant electric-car battery factory.

. . .

(p. A15) At the same time, investment in American manufacturing is hitting a 50-year high, fueled by new federal tax breaks to lift microchip and clean-tech production. Since 2021, companies have announced plans to spend at least $525 billion on factories for semiconductors, batteries, solar panels and more.

In Georgia, where dozens of electric vehicle companies and suppliers are setting up shop, the state’s largest utility now expects 16 times as much growth in electricity demand this decade as it did two years ago.

Millions of Americans are also buying plug-in vehicles and electric heat pumps for their homes, spurred by recent federal incentives. In California, one-fifth of new cars sold are electric, and officials estimate that E.V.s could account for 10 percent of power use during peak hours by 2035.

. . .

So far, one state that has kept pace with explosive demand is Texas, where electricity use has risen 29 percent over the past decade, partly driven by things like bitcoin mining, liquefied natural gas terminals and the electrification of oil fields. Texas’s streamlined permitting process allows wind, solar and battery projects to get built and connected faster than almost anywhere else, and the state zoomed past California last year to lead the nation in large-scale solar power.

“Texas still has problems, but there’s a lot to learn from how the state makes it easier to build clean energy,” said Devin Hartman, director of energy and environmental policy at the R Street Institute.

For the full story, see:

Brad Plumer and Nadja Popovich. “Energy Appetite in U.S. Endangers Goals on Climate.” The New York Times (Monday, March 17, 2024): A1 & A15.

(Note: ellipses, and bracketed year, added.)

(Note: the online version of the story has the date March 14, 2024, and has the title “A New Surge in Power Use Is Threatening U.S. Climate Goals.”)

Musk Fights for Right of Individuals in Sweden to Enter into Contracts

(p. A15) Sweden is the West’s most corporatist society. Powerful interest groups, often described as “social partners,” use collective bargaining to set rents for apartments and wages earned in labor markets.

This model is being challenged by Tesla CEO Elon Musk, who is refusing to enter into collective wage agreements with Swedish trade unions. The unions have responded with strikes and blockades on Tesla operations in the country.

. . .

Liberal democracy presupposes fundamental rights and freedoms. Some of these, such as the freedoms of opinion, press and expression, are enshrined in the Swedish constitution. But the right of the individual to enter into contracts isn’t similarly guaranteed.

. . .

Liberal democracy is being threatened globally by growing populist and illiberal movements. The government in Stockholm should counteract this threat by strengthening people’s individual rights and freedoms in the Swedish constitution. If this happens, Mr. Musk will have given Sweden a great gift.

For the full commentary, see:

Lars Jonung. “Musk Fights Sweden’s Unions.” The Wall Street Journal (Wednesday, February 14, 2024): A15.

(Note: ellipses added.)

(Note: the online version of the commentary has the date February 13, 2024, and has the same title as the print version.)