Category: Government

When Humans Control Animals, Their Wily Resilience Can Cause “Unforeseen Consequences”

(p. A15) For the past three years, a gray squirrel has set out to ruin my life, chewing leaves off my beloved exotic hibiscus and geraniums.

. . .

. . . , Mary Roach’s “Fuzz: When Nature Breaks the Law” makes me feel grateful that my nemesis is only a rodent, and that I live in Ohio, not Colorado or India. My refrigerator will not be emptied by a bear; I will not be throttled by a leopard while taking out the compost.

. . .

There’s something demonic at work in India’s leopards and macaques, but the dilemma finds its root in human behavior. For centuries, feeding monkeys has been considered a religious offering, but this ritual has fueled a certain conviction on the monkeys’ part that humans are in service to them. Ms. Roach’s attempts to pin down government officials on how they might tackle the problem (including hiring more monkey catchers and staffing more monkey sterilization centers) are hilariously convoluted and laced with bizarre anecdotes. She’s passed from one office to the next and back again, never getting an answer. Before redirecting her, one official “veered off into a story about a macaque that got inside the All India Institute of Medical Sciences and took to pulling IV needles out of patients’ arms and sucking the glucose like a child with a straw in a pop bottle.”

During World War II, the U.S. military established a naval air station on Midway Atoll, the strategically significant string of islets halfway between North America and Asia. But the islands turned out to be also a significant nesting ground for thousands of albatrosses, and the result was hundreds of collisions between the airplanes and the huge soaring birds. It is heartbreaking to read of sailors being made to club the long-living albatrosses—80,000 in one assault, 21,000 in another—to reduce the population. Still, nature prevailed. “For a brief time the hazard to aircraft was reduced,” read one report. “The following season there appeared to be as many albatrosses as before.” After every possible deterrent and lethal attack on the gentle birds failed, the air base was closed and in 1993 converted into a refuge. The contrast between this midcentury horror and the reverence shown earlier this year for Wisdom, the 70-year-old Laysan albatross still nesting on Midway, could hardly be more stark.

. . .

This book is largely about the unspooling of unforeseen consequences, and our feeble attempts to put the animal genies we’ve freed back into their bottles.

For the full review, see:

Julie Zickefoose. “BOOKSHELF; Rebellious Nature.” The Wall Street Journal (Tuesday, Nov. 2, 2021): A15.

(Note: ellipses added.)

(Note: the online version of the review has the date November 1, 2021, and has the title “BOOKSHELF; ‘Fuzz’ Review: Rebellious Nature.”)

The book under review is:

Roach, Mary. Fuzz: When Nature Breaks the Law. NY: W. W. Norton & Company, 2021.

Asteroids as Another Existential Threat

Do we best prepare for uncertain existential future threats by huge centrally planned government spending, or by allowing the flourishing of general purpose technologies and nimble entrepreneurs?

(p. C4) The most immediate threat isn’t from the largest or smallest asteroids but from those in between. Over the past two decades, asteroid hunters with NASA and other international space agencies have identified and tracked the orbits of more than 20,000 asteroids—also known as near-Earth objects—that pass through our neighborhood as they orbit the sun. Of those, about 2,000 are classified as potentially hazardous—asteroids that are large enough (greater than 150 yards in diameter) to cause local destruction and that come close enough to Earth to someday pose a threat.

The good news is that scientists don’t expect any of these known asteroids to collide with Earth within at least the next century. Some will come pretty close, though: On an unlucky Friday the 13th in April 2029, the thousand-foot-wide asteroid Apophis will pass a mere 19,000 miles from Earth—closer than the satellites that bring us DISH TV.

But here’s the bad news: Hundreds of thousands of other near-Earth asteroids, both large and small, haven’t been identified. We have no idea where they are and where they are going. On Feb. 15, 2013, a relatively small, 60-foot-wide asteroid traveling at 43,000 mph exploded in the atmosphere near the Russian city of Chelyabinsk, sending out a blast wave that injured 1,500 people. No one had seen the asteroid coming.

We need to find and track these unknown invaders as soon as possible. But while NASA’s “planetary defense” budget has been steadily increasing over the past decade, the $150 million allocated in 2019 for asteroid detection, asteroid tracking and related programs amounts to less than 1% of the space agency’s $21.5 billion budget.

For the full commentary, see:

Gordon L. Dillow. “The Asteroid Peril Isn’t Science Fiction.” The Wall Street Journal (Saturday, July 5, 2019): C4.

(Note: the online version of the commentary has the date July 5, 2019, and has the same title as the print version.)

Dillow’s commentary is related to his book:

Dillow, Gordon L. Fire in the Sky: Cosmic Collisions, Killer Asteroids, and the Race to Defend Earth. New York: Scribner, 2019.

Biden’s Cancer “Moonshot Is 100 Percent Hype”

(p. A17) WASHINGTON — President Biden unveiled a plan on Wednesday to reduce the death rate from cancer by at least 50 percent over the next 25 years — an ambitious new goal, he said, to “supercharge” the cancer “moonshot” program he initiated and presided over five years ago as vice president.

Mr. Biden, joined by his wife, Jill Biden, and Vice President Kamala Harris, also announced a campaign to urge Americans to undergo screenings that were missed during the coronavirus pandemic.

. . .

More screenings are not the answer — the only cancers for which screening has indisputably lowered the death rate are colon and cervical. Death rates for other cancers, like breast, have fallen, but a large part of the drop, if not all of it, is because of improved treatment, said Donald A. Berry, a biostatistician at the University of Texas M.D. Anderson Cancer Center who has spent decades studying these issues.

“Everybody loves early detection, but it comes with harms,” he said — principally, the harm of finding and treating tumors that do not need to be treated because they are innocuous. “The harms we know, but the benefits of screening are very uncertain,” he said.

If the age-adjusted cancer death rate were to plunge by 50 percent, it would have to be because cancers were being cured. Some treatments, like a drug that treats chronic myelogenous leukemia, have slashed death rates for that disease, but such marked effects in cancer are few and far between.

. . .

The White House billed the event as a fresh push by the president to “reignite” the moonshot program and “end cancer as we know it.”

. . .

Yet one Wall Street analyst who specializes in biotechnology and pharmaceuticals said that the time, money and effort might be better spent on initiatives to prevent cancer, like reducing smoking and rates of obesity. The Centers for Disease Control and Prevention says being obese increases a person’s risk of cancer. And reducing smoking is a proven way to cut the cancer death rate.

“This moonshot is 100 percent hype; this is the absolute wrong way to do this,” said the analyst, Stephen Brozak, the president of WBB Securities.

Presidents since Richard M. Nixon have sought to tackle cancer, of which there are more than 100 types of disease that can vary in how they grow, spread and respond to treatment. The cancer institute estimates that nearly 40 percent of men and women will be diagnosed with some type of cancer at some point during their lifetimes. The American Cancer Society estimates there will be 1.9 million new cases of cancer in the United States this year, and more than 609,000 cancer deaths.

For the full story, see:

Sheryl Gay Stolberg and Gina Kolata. “President Aims to Cut The Cancer Death Rate In Half Over 25 Years.” The New York Times (Thursday, February 3, 2022): A17.

(Note: ellipses added.)

(Note: the online version of the story has the date Feb. 2, 2022, and has the title “Biden Presents Ambitious Plan to Cut Cancer Death Rate in Half.”)

Expert Medical Advice Often Flip-Flops

(p. D6) A History of Medical Flip-Flops

Shifting medical advice is surprisingly common, and it tends to fall into three categories: emerging guidance, replacement advice and reversals.

Emerging guidance comes during times of crisis — like pandemics — and is destined to change quickly. In the past several months, guidance about the best way to treat Covid patients, masks to prevent transmission and the limits of vaccine protection have all shifted as knowledge of the coronavirus and its variants has evolved.

Sometimes it’s hard to tell the difference between replacement advice, which is issued when research improves on advice that came before it, and a full reversal, which comes about because a common medical practice got ahead of the science and never actually worked or even caused harm. Here are some examples of true medical flip-flops in recent years.

MENOPAUSE HORMONES TO PROTECT THE HEART: In 2002, decades of advice about the heart benefits of menopause hormones seemed to change overnight when a major study called the Women’s Health Initiative was halted after researchers detected more heart attacks in the women taking hormones. In hindsight, doctors had misinterpreted data from observational research. The current advice: Hormones can relieve menopause symptoms but shouldn’t be used for chronic disease prevention.

VIOXX AS A LOWER-RISK ARTHRITIS TREATMENT: In 1999, the Food and Drug Administration approved Vioxx as a breakthrough pain reliever because it lowered the risk of gastrointestinal problems. But by 2004, Merck had withdrawn the drug because studies showed it significantly raised the risk of heart attack.

ARTHROSCOPIC SURGERY ON AGING KNEES: For years, the partial removal of torn meniscus tissue was the most common orthopedic procedure in the United States, with about 700,000 performed a year. In 2013, a researcher in Finland compared the operation to a “sham” procedure and found there was no benefit. Most doctors now recommend physical therapy instead.

VITAMIN MEGADOSES TO LOWER CANCER AND HEART RISK: For years, doctors believed various vitamins could lower risk for cancer and heart disease, but a number of studies showed just the opposite. A study of beta carotene and vitamin A found that the supplements actually increased the risk of lung cancer in male smokers. A study of vitamin E and selenium, thought to protect against prostate cancer, increased risk for the disease.

STENTS FOR STABLE HEART DISEASE: Doctors used to insert stents — tiny wire mesh tubes that prop open arteries — in millions of otherwise stable patients with heart disease. A study found that the surgical procedure was no better than drug therapy for preventing heart attacks.

Dr. Vinay Prasad, associate professor at the University of California San Francisco, and Dr. Adam S. Cifu, a professor of medicine at the University of Chicago Department of Medicine, coined the term “medical reversal” and concluded that about 40 percent of common medical practices that they reviewed turned out to be useless or harmful. In their book, “Ending Medical Reversal: Improving Outcomes, Saving Lives,” they noted that most of these failed treatments were initially embraced because they were based on logical reasoning.

“The thing that’s often behind reversal: All of these things have a good story, they have good pathophysiological rationale,” Dr. Cifu said. “They should work. But things only work if they’ve been shown in people to work, and people are so complicated.”

For the full story, see:

Tara Parker-Pope. “Shifting Medical Advice Is a Feature, Not a Bug.” The New York Times (Tuesday, November 2, 2021): D6.

(Note: the online version of the story was updated Oct. 24, 2021, and has the title “Is the New Aspirin Advice a Medical Flip-Flop, or Just Science?” The paragraphs on menopause hormones to protect the heart and on vitamin megadoses to lower cancer and heart risk appear in the online version, but not in the print version.)

The book co-authored by Prasad and mentioned above is:

Prasad, Vinayak K., and Adam S. Cifu. Ending Medical Reversal: Improving Outcomes, Saving Lives. Baltimore: Johns Hopkins University Press, 2015.

Calcutta Commuters Avoid Slow Unreliable Trams Because “People Want to Move Fast”

(p. A4) “You get all the flavors of Calcutta here, so it’s the best way to travel,” said a medical student, Megha Roy, riding the tram with two friends. She used the Anglicized version of Kolkata, which residents deploy interchangeably with its current spelling and pronunciation.

The three friends had jumped onboard spontaneously, with no clear idea of where the tram was going, or when it was scheduled to get there. But it didn’t really matter. The ride itself was an unexpected treat.

“It’s like a fairy tale,” Ms. Roy said.

. . .

. . . the authorities say that while trams should remain a part of the transit mix, buses and the city’s metro system better serve 21st-century riders in the city of some 15 million people.

. . .

“Scientifically, economically, environmentally, there is no reason to convert the tramways for buses,” said Debasish Bhattacharyya, president of the Calcutta Tram Users’ Association.

But the scene at one tram stop suggested commuters may feel differently. Fewer than half a dozen people were waiting for the tram, while nearby, hundreds were piling onto buses that sagged under the weight of so many passengers, belching black plumes of diesel exhaust as they careened over the tram’s tracks and onto the street.

Admittedly, neither speed nor punctuality are hallmarks of the trams, which must contend with a mélange of traffic on their routes: trucks, buses, cars, vintage yellow Ambassador taxis, rickshaws manual and electric, pedestrians, herds of goats and the occasional cow.

“Nobody knows when the next car will come,” Mr. Bhattacharyya said. “They say this is the control room, but nothing is controlled, everything is scattered,” he said, gesturing to a hub of the tram system in central Kolkata.

. . .

Aboard a tram crawling along Lenin Sarani, one of central Kolkata’s main thoroughfares and named in honor of the Russian revolutionary, Sumit Chandra Banerjee, a ticket taker, said he looked forward to mandatory retirement when he turned 60 in October [2021].

. . .

Many of Kolkata’s urban landmarks — from cinemas and bookstores to museums and hospitals — were built near the tracks. One of those institutions was Das Gupta Books, founded in 1886.

Aranda Das Gupta, the shop’s fourth-generation managing director, called the tram a “beautiful journey,” while acknowledging that it takes “maximum time.”

“Nowadays,” he said, “people want to move fast.”

For the full story, see:

Emily Schmall. “INDIA DISPATCH; Kolkata Is Letting Its ‘Fairy Tale’ Trams Waste Away.” The New York Times (Friday, September 3, 2021): A4.

(Note: ellipses, and bracketed year, added.)

(Note: the online version of the story has the date Sept. 2, 2021, and has the title “INDIA DISPATCH; Kolkata’s ‘Fairy Tale’ Trams, Once Essential, Are Now a Neglected Relic.”)

Feds Impede Consumer Choice by Going Back to Incandescent Ban

(p. A16) In 2019, the Trump administration blocked a rule designed to phase out older incandescent bulbs, calling it unnecessary and an impediment to consumer choice.

With the move, the administration heeded to both industry demands as well as free market proponents who have long railed against tougher efficiency regulations for consumer appliances and goods, like energy-saving bulbs or water-saving dishwashers, as governmental overreach.

“The new bulb is many times more expensive, and I hate to say it, it doesn’t make you look as good,” Donald J. Trump, the former president, quipped at a White House meeting in 2019, referring to an early common complaint that LEDs emit a harsher light, though recent LED lights come in warmer hues. “We’re bringing back the old light bulb,” he later told a rally in Michigan.

The Biden administration has moved to reinstate the standards. But in a letter to the Department of Energy last year, NEMA, the industry group, urged federal rules to allow companies to manufacture and import inefficient bulbs for at least another year, followed by another year or more to sell out stockpiled inventory.

For the full story, see:

Hiroko Tabuchi. “Obsolete Bulbs Fill the Shelves At Dollar Stores.” The New York Times (Monday, January 24, 2022): A1 & A16.

(Note: the online version of the story has the date January 23, 2022, and has the title “Old-Fashioned, Inefficient Light Bulbs Live On at the Nation’s Dollar Stores.”)

Instead of Centralizing With C.D.C., the Need for Speed Requires “Clinical and Commercial Labs to Create and Deploy Tests”

(p. A22) The faulty coronavirus testing kits developed by the Centers for Disease Control and Prevention in the early weeks of the pandemic were not only contaminated but had a basic design flaw, according to an internal review by the agency.

Health officials had already acknowledged that the test kits were contaminated, but the internal report, whose findings were published in PLOS ONE on Wednesday, also documented a design error that caused false positives.

. . .

The C.D.C.’s test was designed to detect three distinct regions, or target sequences, of the virus’s genetic material. The test kits contain a set of what are known as primers, which bind to and make copies of the target sequences, and probes, which produce a fluorescent signal when these copies are made, indicating that genetic material from the virus is present.

The primers and probes need to be carefully designed so that they bind to the target sequences and not to each other. In this case, that did not happen. One of the probes in the kit sometimes bound to one of the primers, producing the fluorescent signal and generating a false positive.

“It’s something that should have been caught in the design phase,” said Susan Butler-Wu, a clinical microbiologist at the Keck School of Medicine of the University of Southern California. “That’s one thing that you check for.”

. . .

The bigger lesson, Dr. Butler-Wu said, is that the responsibility for developing diagnostic tests should be distributed more widely during a public health emergency. Rather than relying on the C.D.C. to be the sole test developer, officials could also enlist clinical and commercial labs to create and deploy tests.

“It’s great that there’s all these additional checks in place, but what are you going to do when there’s a new emerging pathogen and we need to respond quickly?” she said. “I don’t think that’s a viable model for responding to a pandemic.”

For the full story, see:

Emily Anthes. “C.D.C. Finds Design Error In Testing Kits It Distributed.” The New York Times Thursday, December 16, 2021): A22.

(Note: ellipses added.)

(Note: the online version of the story has the date Dec. 15, 2021, and has the title “C.D.C. Virus Tests Were Contaminated and Poorly Designed, Agency Says.”)

The PLOS ONE article mentioned above is:

Lee, Justin S., Jason M. Goldstein, Jonathan L. Moon, Owen Herzegh, Dennis A. Bagarozzi, Jr., M. Steven Oberste, Heather Hughes, Kanwar Bedi, Dorothie Gerard, Brenique Cameron, Christopher Benton, Asiya Chida, Ausaf Ahmad, David J. Petway, Jr., Xiaoling Tang, Nicky Sulaiman, Dawit Teklu, Dhwani Batra, Dakota Howard, Mili Sheth, Wendi Kuhnert, Stephanie R. Bialek, Christina L. Hutson, Jan Pohl, and Darin S. Carroll. “Analysis of the Initial Lot of the CDC 2019-Novel Coronavirus (2019-nCoV) Real-Time RT-PCR Diagnostic Panel.” PLOS ONE 16, no. 12 (Dec. 15, 2021). DOI: 10.1371/journal.pone.0260487.

Majority of Economists Say Price Controls Would Fail to “Successfully” Reduce Inflation

(p. B1) America’s recent inflation spike has prompted renewed interest in an idea that many economists and policy experts thought they had long ago left behind for good: price controls.

The federal government last imposed broad-based limits on how much private companies could charge for their goods and services in the 1970s, when President Richard M. Nixon ushered in wage and price freezes over the course of a few years. That experiment was widely regarded as a failure, and ever since, the phrase “price controls” has, at least for many people, called to mind images of product shortages and bureaucratic overreach. In recent decades, few economists have bothered to study the idea at all.

. . .

(p. B2) Artificially holding down prices leads to shortages, inefficiencies or other unintended consequences, like an increase in black-market activity. And while some economists say price controls on specific products can make sense in specific situations — to prevent price-gouging after a natural disaster, for example — most argue that they are a poor tool for fighting inflation, which is a broad increase in prices.

In a recent survey of 41 academic economists conducted by the University of Chicago’s Booth School of Business, 61 percent said that price controls similar to those imposed in the 1970s would fail to “successfully reduce U.S. inflation over the next 12 months.” Others said the policy might bring down inflation in the short-term but would lead to shortages or other problems.

“Price controls can of course control prices — but they’re a terrible idea!” David Autor, an economist at the Massachusetts Institute of Technology, wrote in response to the survey.

. . .

“It sounds good: Your wages are going to be higher, and your prices are going to be the same,” said Lawrence H. Summers, a Harvard University economist. “Unless there is a mechanism for producing more stuff, it’s just going to result in longer queues.”

For the full story, see:

Ben Casselman and Jeanna Smialek. “A Throwback Idea Returns As Inflation Rears Its Head.” The New York Times (Monday, January 17, 2022): B1-B2.

(Note: ellipses added.)

(Note: the online version of the story was updated Jan. 13, 2022, and has the title “Price Controls Set Off Heated Debate as History Gets a Second Look.”)

“Fission Is in Fashion” and Is Over-Regulated

(p. A15) Fission is in fashion as drawbacks of intermittent wind and solar power emerge.

. . .

Regulatory limits on annual exposure around nuclear plants are less than a year’s background radiation from rocks and cosmic rays. Radiation scientists now know that people can safely absorb that much radiation every day because DNA is repaired and cells are replaced constantly in living beings. Yet regulators’ mandated limits, at a thousandth of what’s really harmful, create fright of all radiation. No one needed to be evacuated at Fukushima or around Chernobyl, places where thousands died from unwarranted fear and relocation stress.

For the full commentary, see:

Robert Hargraves. “If You Want Clean Power, Go Fission.” The Wall Street Journal (Thursday, January 27, 2022): A15.

(Note: ellipsis added.)

(Note: the online version of the commentary has the date Jan. 26, 2022, and has the same title as the print version.)

DeSantis Upgrades Infrastructure to Mitigate Flooding

(p. A5) The Republican governor, unlike many of his Democratic counterparts, didn’t use the term “climate change” or endorse specific policies aimed at combating factors that most climate scientists say are driving warming, such as greenhouse-gas emissions. He focused on responding to the effects of a warming climate.

“What I’ve found is people, when they start talking about things like global warming, they typically use that as a pretext to do a bunch of left-wing things,” said Mr. DeSantis at the event. “We’re not doing any left-wing stuff.”

Governors and lawmakers in several Republican-led states, including Idaho, South Carolina and Texas, are taking a similar approach as concern about climate change increases. After natural disasters that research suggests are becoming more frequent and intense, they are taking measures such as infrastructure upgrades to mitigate flooding, wildfires and severe storms. Such moves are vital to their states’ economic livelihood, they say.

. . .

At the Oldsmar event, Mr. DeSantis outlined a proposal to dedicate more than $270 million to 76 projects aimed at bolstering defenses against rising sea levels and flooding. “We’re a low-lying state, we’re a storm-prone state, and we’re a flood-prone state,” he said.

For the full story, see:

Arian Campo-Flores. “Republicans Adjust Climate Message.” The Wall Street Journal (Monday, January 24, 2022): A5.

(Note: ellipsis added.)

(Note: the online version of the story has the date Jan. 23, 2022, and has the title “Millions Have Lost a Step Into the Middle Class, Researchers Say.”)

Machiavelli Described the Methods of Tyrants

(p. C12) But anyone who observes politics, business or even the loftiest social institutions will know that the world is rife with backstabbers, hypocrites and ethical ne’er-do-wells all thriving at the highest levels—beyond the reach of law or hashtag.

. . .

Machiavelli’s gift, Mr. Boucheron argues, was “naming with precision that which was happening.” He explains the behavior of tyrants not to excuse them, but to show the rest of us what to look out for, in the clearest terms possible. Machiavelli’s “lucidity,” says Mr. Boucheron, was the “weapon of the despairing.”

Other political thinkers have read Machiavelli this way. Jean-Jacques Rousseau wrote in “The Social Contract” that Machiavelli was not advising tyrants but “instructing the people on what they have to fear.” John Adams credited Machiavelli for helping him think through the likely threats to a young American republic.

For the full review, see:

Philip Delves Broughton. “A Poetics for Tyrants.” The Wall Street Journal (Saturday, January 25, 2020): C12.

(Note: ellipsis added.)

(Note: the online version of the review has the date January 24, 2020, and has the title “‘Machiavelli’ Review: A Poetics for Tyrants.”)

The book under review is:

Boucheron, Patrick. Machiavelli: The Art of Teaching People What to Fear. Translated by Willard Wood. New York: Other Press, 2020.