Though Visible, Not Everyone Saw the Unexpected Buckyball

(p. A24) Robert F. Curl Jr., who shared the 1996 Nobel Prize in Chemistry as one of the discoverers of remarkably simple but completely unexpected carbon molecules known as buckyballs, died on July 3 at a retirement home in Houston. He was 88.

His death was announced by Rice University, where Dr. Curl was a professor emeritus of chemistry.

Buckyballs, with their round, hollow structure, upended chemists’ notions of what was possible for the shapes of molecules. A flood of scientists started studying them, spurring the nascent field of nanotechnology and dreams of building molecule-size machines.

. . .

The finding was serendipitous, because they had been looking for something else.

“You could argue it wasn’t any of our areas of interest,” James R. Heath, a graduate student of Dr. Smalley’s who performed many of the buckyball experiments, said in an interview.

. . .

For the experiment, Dr. Kroto was interested in molecules containing long chains of carbon that had been observed in interstellar space. He hypothesized that the long-chain molecules were created in the atmospheres of carbon-rich red giant stars.

. . .

At a science conference in 1984, Dr. Kroto ran into Dr. Curl, an old friend. Dr. Curl told him about an apparatus of Dr. Smalley’s that used a laser to create an intensely hot vapor that coalesced into clusters. Dr. Kroto realized that this apparatus could create conditions similar to those in the atmosphere of a red giant.

. . .

. . . Dr. Smalley finally agreed to try it, and the three professors, along with Dr. Heath and two graduate students, started their work.

They indeed discovered the long carbon chains that Dr. Kroto had wanted to find.

They also found something else — the buckyballs.

Dr. Heath said Dr. Curl provided a healthy dose of skepticism during the 11-day whirlwind of discovery.

“All of us were like excitable kids,” Dr. Heath said. “And Bob was like the adult in the room. And he would come up with reasons that we had to go back and test and make sure that this was right or that was correct. We all viewed Bob not like he was a devil’s advocate — more like he was an insurance policy. If Bob agreed with you, you were probably right.”

It turned out that the Exxon experiments had also created small numbers of buckyballs, but those researchers had overlooked them in their data. At Rice, the scientists realized what they had found.

For the full obituary see:

Kenneth Chang. “Robert F. Curl Jr., 88, Nobel Prize Winner in Chemistry.” The New York Times (Thursday, July 21, 2022): A24.

(Note: ellipses added.)

(Note: the online version of the obituary has the date July 20, 2022, and has the title “Robert F. Curl Jr., Nobel Prize Winner in Chemistry, Dies at 88.”

Wary, Subdued Infants Tend to Grow into “Anxious, Inhibited Adults”

(p. A21) Prof. Jerome Kagan, a Harvard psychologist whose research into temperament found that shy infants often grow up to be anxious and fearful adults because of their biological nature as well as the way they were nurtured, died on May 10 in Chapel Hill, N.C.

. . .

Professor Kagan argued in more than two dozen books, including the widely praised “The Nature of the Child” (1984), that some children were genetically wired to worry and that they proved to be more resilient than expected as they passed from one stage of maturity to another. He also contended that the specifics of parenting were often not as crucial to a child’s future as parents think, although the child’s natural predisposition to be shy or exuberant could be altered by experience.

. . .

Professor Kagan and his collaborators, including Howard A. Moss and Nancy C. Snidman, pioneered the reintroduction of physiology as a determinant of psychological characteristics that could be measured in the brain.

They derived their conclusions from lengthy studies that started with the videotaped reactions of toddlers and infants as young as 4 months to various stimuli — unfamiliar objects, people and situations — and correlated those reactions to their temperament as teenagers and beyond, as measured in interviews.

The wary ones who were subdued, shy and hovered around their mothers or who fussed, thrashed around and cried — about 15 percent of the total — tended to become anxious, inhibited adults. Another 15 percent who were ebullient as infants and embraced every new toy and interviewer tended to develop into fearless children and adolescents.

Professor Kagan acknowledged that as an ideological liberal he had originally believed that all individuals were capable of achieving similar goals if afforded the same opportunities. “I was so resistant to awarding biology much influence,” he wrote.

For the full obituary see:

Sam Roberts. “Jerome Kagan, 92, Psychologist Who Tied Temperament to Biology, Is Dead.” The New York Times (Saturday, May 22, 2021): A21.

(Note: ellipses added.)

(Note: the online version of the obituary has the date May 21, 2021, and has the title “Jerome Kagan, Who Tied Temperament to Biology, Dies at 92.”

Kagan’s book, mentioned above, is:

Kagan, Jerome. The Nature of the Child (Tenth Anniversary Edition). New York: Basic Books, 1994.

A.I. Cannot Learn What 4-Year-Old Learns From Trial-And-Error Experiments

(p. C3) A few weeks ago a Google engineer got a lot of attention for a dramatic claim: He said that the company’s LaMDA system, an example of what’s known in artificial intelligence as a large language model, had become a sentient, intelligent being.

Large language models like LaMDA or San Francisco-based Open AI’s rival GPT-3 are remarkably good at generating coherent, convincing writing and conversations—convincing enough to fool the engineer. But they use a relatively simple technique to do it: The models see the first part of a text that someone has written and then try to predict which words are likely to come next. If a powerful computer does this billions of times with billions of texts generated by millions of people, the system can eventually produce a grammatical and plausible continuation to a new prompt or a question.

. . .

In what’s known as the classic “Turing test,” Alan Turing in 1950 suggested that if you couldn’t tell the difference in a typed conversation between a person and a computer, the computer might qualify as intelligent. Large language models are getting close. But Turing also proposed a more stringent test: For true intelligence, a computer should not only be able to talk about the world like a human adult—it should be able to learn about the world like a human child.

In my lab we created a new online environment to implement this second Turing test—an equal playing field for children and AI systems. We showed 4-year-olds on-screen machines that would light up when you put some combinations of virtual blocks on them but not others; different machines worked in different ways. The children had to figure out how the machines worked and say what to do to make them light up. The 4-year-olds experimented, and after a few trials they got the right answer. Then we gave state-of-the-art AI systems, including GPT-3 and other large language models, the same problem. The language models got a script that described each event the children saw and then we asked them to answer the same questions we asked the kids.

We thought the AI systems might be able to extract the right answer to this simple problem from all those billions of earlier words. But nobody in those giant text databases had seen our virtual colored-block machines before. In fact, GPT-3 bombed. Some other recent experiments had similar results. GPT-3, for all its articulate speech, can’t seem to solve cause-and-effect problems.

If you want to solve a new problem, googling it or going to the library may be a first step. But ultimately you have to experiment, the way the children did. GPT-3 can tell you what the most likely outcome of a story will be. But innovation, even for 4-year-olds, depends on the surprising and unexpected—on discovering unlikely outcomes, not predictable ones.

For the full commentary see:

Alison Gopnik. “What AI Still Doesn’t Know How To Do.” The Wall Street Journal (Saturday, July 16, 2022): C3.

(Note: ellipsis added.)

(Note: the online version of the commentary has the date July 15, 2022, and has the same title as the print version.)

The “Intellect” and “Bravado” Behind the Success of Thiel, Musk, and the “PayPal Mafia”

(p. C7) Next week marks the 20th anniversary of PayPal becoming a publicly traded company. The IPO valued the online payments processor at nearly $1 billion—an eye-opening sum at the time. Back in the day, technology firms marked such occasions with glitzy celebrations. PayPal took a different path. Its youthful employees gathered in the parking lot of their Palo Alto, Calif., office building, where the company’s enigmatic chief executive, Peter Thiel, performed a keg stand and then played 10 simultaneous games of speed chess, winning nine of them.

Jimmy Soni tells that story and many others in “The Founders,” a gripping account of PayPal’s origins and a vivid portrait of the geeks and contrarians who made its meteoric rise possible. His richly reported narrative includes corporate intrigue, workplace hijinks, breakthrough innovation and first-class nerdiness.

. . .

Julie Anderson, one of X.com’s early employees, dropped the company’s California-based telephone customer-service provider and relaunched the service in Nebraska. Why there? Because many of her relatives lived there.

. . .

Confirming a cliché, staffers do spend all night at the office—sometimes sleeping under their desks, though not always. “There’s this massive value that you harness when you’re doing an all-nighter,” says Mr. Levchin, “when you’ve gone for presumably seven or eight hours of work, and you’re really getting up to a point when something’s about to be born—and then you go for eight more hours! And instead of stopping to go to sleep and letting these ideas dissipate, you actually focus on the findings you’ve made in the last few hours, and you just go crazy and do some more of that.”

. . .

Why did PayPal thrive when others—eMoneyMail, PayPlace, c2it—failed? One key was limiting the losses from fraud. If the company had taken a traditional approach, observes a member of the fraud-analytics team, it “would have hired people who had been building logistic regression models for banks for twenty years but never innovated.” Instead it turned to young, open-minded engineers who devised unorthodox methods.

. . .

. . . “The Founders” makes crystal-clear that PayPal’s human capital—a potent cocktail of intellect, bravado and competitiveness, complemented by the occasional keg stand—laid the foundation for success.

For the full review, see:

Matthew Rees. “Making the Future Click.” The Wall Street Journal (Saturday, Feb. 12, 2022): C7.

(Note: ellipses added.)

(Note: the online version of the review has the date February 11, 2022, and has the title “‘The Founders’ Review: Making the Future Click.”)

The book under review is:

Soni, Jimmy. The Founders: The Story of PayPal and the Entrepreneurs Who Shaped Silicon Valley. New York: Simon & Schuster, 2022.

The “Perceptually Divergent” Are Open to How Species Differ in Their Sensory Trade-Offs

(p. C1) That I found myself surprised at so many moments while reading “An Immense World,” Ed Yong’s new book about animal senses, speaks to his exceptional gifts as a storyteller — . . .

. . .

(p. C4) Yong’s book is funny and elegantly written, mercifully restrained when it comes to jargon, though he does introduce a helpful German word that he uses throughout: Umwelt. It means “environment,” but a little more than a century ago the Baltic German zoologist Jakob von Uexküll used it to refer more specifically to that sensory bubble — an animal’s perceptual world.

. . .

The human Umwelt will necessarily shape how we apprehend other Umwelten. “An Immense World” inevitably refers to the philosopher Thomas Nagel’s foundational essay on this struggle, “What Is It Like to Be a Bat?”

But some humans might be more open-minded than others. A number of the sensory biologists Yong meets are perceptually divergent, seeing color differently or having difficulty remembering familiar faces: “Perhaps people who experience the world in ways that are considered atypical,” he writes, “have an intuitive feeling for the limits of typicality.”

When it comes to sight, there’s a trade-off between sensitivity and resolution; humans tend to have extraordinary visual acuity during the day but have a much harder time seeing at night, while animals with better night vision don’t register the crisp images at a distance that we do. “Senses always come at a cost,” Yong writes. “No animal can sense everything well.” The world inundates us with stimuli. Registering some of it is taxing enough; fully processing the continuous deluge of it would be overwhelming.

For the full review, see:

Jennifer Szalai. “An Enthralling Tour Of Nonhuman Reality.” The New York Times (Thursday, June 23, 2022): C1 & C4.

(Note: ellipses added.)

(Note: the online version of the review has the date June 22, 2022, and has the title “‘An Immense World’ Is a Thrilling Tour of Nonhuman Perception.”)

The book under review is:

Yong, Ed. An Immense World: How Animal Senses Reveal the Hidden Realms around Us. New York: Random House, 2022.

When HR Team-Building Is on Fire

(p. B2) Walking barefoot across hot coals, an ancient religious ritual popularized in recent years as a corporate team-building exercise, has once again bonded a group of co-workers through the shared suffering of burned feet.

In the latest case of the stunt going wrong, 25 employees of a Swiss ad agency were injured Tuesday [June 14, 2022] evening while walking over hot coals in Zurich, officials said. Ten ambulances, two emergency medical teams and police officers from multiple agencies were deployed to help, according to the Zurich police. Thirteen people were briefly hospitalized.

. . .

Mr. Willey, who taught for years at the University of Pittsburgh, once shared the world record for the longest distance walked on hot coals.

The promises made by corporate retreat organizers are frequently unjustified, Mr. Willey said.

“They’re telling you that it’s all in your mind, and this will give you powers that will continue,” he said. “It’s not in your mind. Anybody can do it. And I don’t think the confidence you get from it is necessarily going to last that long.”

Mr. Willey said that coals at 1,000 degrees are safe to walk on for 20 feet or more, adding that he walked on coals at that temperature for 495 feet without getting a blister.

On his website, he writes that at a brisk walk your bare foot comes into contact with coals for just around a second, which is not enough time for heat to be transmitted painfully from coals to the human flesh. Both the coals and skin have vastly lower thermal conductivity than, for instance, metal, he said.

But mistakes can lead to injuries. These include curling your toes and trapping a coal between them; walking on coals that are too hot; choosing the wrong type of wood, since some get hotter than others; and performing a fire walk on a beach, where your feet might sink into sand, Mr. Willey said.

For the full story, see:

Alex Traub. “Company’s Team-Building Exercise Involved Hot Coals. It Ended Badly.” The New York Times (Monday, June 20, 2022): B2.

(Note: ellipsis, and bracketed date, added.)

(Note: the online version of the story has the date June 17, 2022, and has the title “Walking on Hot Coals: A Company Event Goes Wrong.”)

“Don’t Give Up and Say There’s No Point”

(p. A18) TOKYO—The world’s oldest verified living person, Kane Tanaka of Japan, has died at age 119.

. . .

According to Japanese news accounts, Ms. Tanaka loved chocolate and carbonated drinks and hoped to live to 120. Her motto was “Don’t give up and say there’s no point. Live with all your heart.”

For the full story, see:

Chieko Tsuneoka. “World’s Oldest Person Dies at 119.” The Wall Street Journal (Tuesday, April 26, 2022): A18.

(Note: ellipsis added.)

(Note: the online version of the story was updated April 25, 2022, and has the title “World’s Oldest Person, Japan’s Kane Tanaka, Dies at 119.” The print version has a longer first sentence than the online version, which is quoted above.)

Workers With Little Choice in the Hours They Work Are Twice as Likely to Seek a New Job

(p. A11) . . . new survey data this week shows that full-time workers have more work-related stress and anxiety than their hybrid and remote counterparts.

Overall satisfaction with their workplace declined by 1.6 times as much for those working five days in the office compared with the other groups, according to the report from Future Forum, a consortium funded by Slack Technologies Inc., Boston Consulting Group and MillerKnoll.

The survey of more than 10,800 knowledge workers across about 20 industries including financial services, consumer goods and technology, comes as companies have been calling workers back to their desks at a higher rate than at any other time during the pandemic.

The discontent reflected in the data among those working in the office every day highlights risks that companies take by giving priority to face time and in-office culture over worker preferences for flexibility coming out of the pandemic, says Brian Elliott, executive leader of Future Forum.

“We were kind of shocked that it was as bad as it was,” he says. “It’s going to impact people’s tendency to resign.”

Of the workers surveyed, about 5,000 are based in the U.S. The share of those workers who are now back in the office five days a week rose from 29% in the last quarter of 2021 to 35% in the first quarter of this year.

Workers with little to no ability to set their own hours were more than 2½ times as likely to look for a new job in the coming year as those who have some say in when they work, according to the survey.

For the full story, see:

Katherine Bindley. “For Many, the Optimal Workweek Is One or Two Days in the Office’.” The Wall Street Journal (Monday, April 25, 2022): A11.

(Note: ellipsis added.)

(Note: the online version of the story was updated April 22, 2022, and has the title “What if the Optimal Workweek Is Two Days in the Office?”)

Dreaming Often Is Nonlinear Problem-Solving

(p. A15) Antonio Zadra and Robert Stickgold, two of the world’s leading researchers in the science of sleep and dreams, have written a remarkable account of what we know and don’t know about this mysterious thing that happens during the night.

. . .

To many, dreams are prophecies, implanted in our brains by God or angels; to others, they exist to encode our memories of the previous day, to others they are simply random neural firings.

. . .

The weight of the evidence supports a more elaborate, nuanced and wondrous version of the memory-encoding hypothesis. Messrs. Zadra and Stickgold have designed a conceptual model they call Nextup (“Network Exploration to Understand Possibilities”), using it to describe the progression of dreams throughout the four sleep stages and their different functions. They debunk the common myth that we only dream during REM sleep and show that, in fact, we are typically dreaming throughout the night and in nonREM sleep states. They tie all of this into the brain’s “default mode network,” in which our minds are wandering and, often, problem-solving. When we’re awake, our brains are so busy attending to the environment that we tend to favor linear connections and thinking; when we allow ourselves to daydream, we solve problems that have distant, novel or nonlinear solutions.

For the full review, see:

Daniel J. Levitin. “Destination Anywhere.” The Wall Street Journal (Saturday, March 6, 2021): C7.

(Note: ellipses added.)

(Note: the online version of the review was updated March 5, 2021, and has the title “‘When Brains Dream’ Review: Night Shift.”)

The book under review is:

Zadra, Antonio, and Robert Stickgold. When Brains Dream: Exploring the Science and Mystery of Sleep. New York: W. W. Norton & Company, 2021.

Gary Becker Foresaw a Cure for Obesity that Daniel Kahneman Wrote Was “Implausible”

I have found much of value in Daniel Kahneman’s Thinking, Fast and Slow. But the following passage is not included in what I value.

A famous example of the Chicago approach is titled A Theory of Rational Addiction; it explains how a rational agent with a strong preference for intense and immediate gratification may make the rational decision to accept future addiction as a consequence. I once heard Gary Becker, one of the authors of that article, who is also a Nobel laureate of the Chicago school, argue in a lighter vein, but not entirely as a joke, that we should consider the possibility of explaining the so-called obesity epidemic by people’s belief that a cure for diabetes will soon become available. He was making a valuable point: when we observe people acting in ways that seem odd, we should first examine the possibility that they have a good reason to do what they do. Psychological interpretations should only be invoked when the reasons become implausible—which Becker’s explanation of obesity probably is.

Source: Kahneman, Daniel. Thinking, Fast and Slow. New York: Farrar, Straus and Giroux, 2011, p. 412.

Gary Becker is vindicated again:

(p. A16) An experimental drug has enabled people with obesity or who are overweight to lose about 22.5 percent of their body weight, about 52 pounds on average, in a large trial, the drug’s maker announced on Thursday.

The company, Eli Lilly, has not yet submitted the data for publication in a peer-reviewed medical journal or presented them in a public setting. But the claims nonetheless amazed medical experts.

“Wow (and a double Wow!)” Dr. Sekar Kathiresan, chief executive of Verve Therapeutics, a company focusing on heart disease drugs, wrote in a tweet. Drugs like Eli Lilly’s, he added, are “truly going to revolutionize the treatment of obesity!!!”

Dr. Kathiresan has no ties to Eli Lilly or to the drug.

. . .

The Eli Lilly study lasted 72 weeks and involved 2,539 participants. Many qualified as obese, while others were overweight but also had such risk factors as high blood pressure, high cholesterol levels, cardiovascular disease or obstructive sleep apnea.

They were divided into four groups. All received diet counseling to reduce their calorie intake by about 500 a day.

One group was randomly assigned to take a placebo, while the other three received doses of tirzepatide ranging from 5 milligrams to 15 milligrams. Patients injected themselves with the drug once a week.

. . .

The medications are among a new class of drugs called incretins, which are naturally occurring hormones that slow stomach emptying, regulate insulin and decrease appetite. The side effects include nausea, vomiting and diarrhea. But most patients tolerate or are not bothered by these effects.

For the full story, see:

Gina Kolata. “Experimental Obesity Drug Produces 20% Weight Loss.” The New York Times (Friday, April 29, 2022): A16.

(Note: ellipses added.)

(Note: the online version of the story was updated May 1, 2022, and has the title “Patients Taking Experimental Obesity Drug Lost More Than 50 Pounds, Maker Claims.” Where there is a slight difference in wording between the online and the print versions, the passages quoted above follow the online version.)

Kahneman’s book is:

Kahneman, Daniel. Thinking, Fast and Slow. New York: Farrar, Straus and Giroux, 2011.

Some Venture Capitalists “Act as Mentors,” Some Install Seasoned Veterans as C.E.O.s, and Some Are “Founder-Friendly,” Allowing Genius “to Do Its Work”

(p. C4) . . . Mallaby never quite settles on the story he wants to tell. He introduces the book by laying out what he intends to do: “to explain the venture-capital mind-set” and “to evaluate venture capital’s social impact.” This mind-set, he says, revolves around the “power law” of his title — the idea that the distribution of phenomena is not “normal” but skewed. Instead of a bell curve, picture a long tail, where “winners advance at an accelerating, exponential rate.” Adapt or die, sink or swim — there’s no middle ground. This is why V.C.s like to talk about “grand slams” and “moon shots”; Peter Thiel says that a fund’s top investment should generate returns so spectacular that it will outperform everything else in the fund put together.

This, clearly, isn’t the kind of logic that has much use for steady, incremental growth, to say nothing of a flourishing middle class. You might therefore wonder about the “social impact” of venture capital, which Mallaby deems to be, on the whole, good. He concedes that “V.C.s as individuals can stumble sideways into lucky fortunes,” or can sometimes do unhelpful things. But he is ultimately bullish on what they have to offer: “Venture capital as a system is a formidable engine of progress — more so than is frequently acknowledged.” That engine, Mallaby reminds us, has funded such ventures as the development of synthetic insulin and, more recently, plant-based alternatives to ecologically damaging meat.

. . .

He gives examples of the different kinds of funds, with their various personalities and philosophies. There are V.C.s who see it as their role to act as mentors and coaches to inexperienced founders. There are V.C.s who insist on installing seasoned outsiders at start-ups to serve as C.E.O.s. There are also “founder-friendly” V.C.s, who promise to be hands-off, allowing genius, no matter how unorthodox or weird, to do its work.

For the full review, see:

Jennifer Szalai. “BOOKS OF THE TIMES; A Funder-Friendly Look at Venture Capital.” The New York Times (Tuesday, February 1, 2022): C4.

(Note: ellipses added.)

(Note: the online version of the review has the date Jan. 31, 2022, and has the title “BOOKS OF THE TIMES; ‘The Power Law’ Is a Funder-Friendly Look at the World of Venture Capital.”)

The book under review is:

Mallaby, Sebastian. The Power Law: Venture Capital and the Making of the New Future. New York: Penguin Press, 2022.