Science – Page 27 – artdiamondblog.com

Scientific Insight Requires Hard Work More than Easy Epiphany

(p. A21) The myth of the finches obscures the qualities that were really responsible for Darwin’s success: the grit to formulate his theory and gather evidence for it; the creativity to seek signs of evolution in existing animals, rather than, as others did, in the fossil record; and the open-mindedness to drop his belief in creationism when the evidence against it piled up.
The mythical stories we tell about our heroes are always more romantic and often more palatable than the truth. But in science, at least, they are destructive, in that they promote false conceptions of the evolution of scientific thought.
Of the tale of Newton and the apple, the historian Richard S. Westfall wrote, “The story vulgarizes universal gravitation by treating it as a bright idea … A bright idea cannot shape a scientific tradition.” Science is just not that simple and it is not that easy.
. . .
Even if we are not scientists, every day we are challenged to make judgments and decisions about technical matters like vaccinations, financial investments, diet supplements and, of course, global warming. If our discourse on such topics is to be intelligent and productive, we need to dip below the surface and grapple with the complex underlying issues. The myths can seduce one into believing there is an easier path, one that doesn’t require such hard work.
But even beyond issues of science, there is a broader lesson to learn, . . . . We all run into difficult problems in life, and we will be happier and more successful if we appreciate that the answers often aren’t quick, or easy.

For the full commentary, see:
LEONARD MLODINOW. “It Is, in Fact, Rocket Science.” The Wall Street Journal (Sat., MAY 16, 2015): A21.
(Note: ellipsis internal to third quoted paragraph, in original; other ellipses, added.)
(Note: the online version of the commentary was updated on MAY 15, 2015.)

Mlodinow’s book, related to the commentary quoted above, is:
Mlodinow, Leonard. The Upright Thinkers: The Human Journey from Living in Trees to Understanding the Cosmos. New York: Pantheon Books, 2015.

Inflation of the Co-Authorship Bubble

Source of graphic: online version of the WSJ article quoted and cited below.

(p. A1) . . . , there has been a notable spike since 2009 in the number of technical reports whose author (p. A10) counts exceeded 1,000 people, according to the Thomson Reuters Web of Science, which analyzed citation data. In the ever-expanding universe of credit where credit is apparently due, the practice has become so widespread that some scientists now joke that they measure their collaborators in bulk–by the “kilo-author.”

Earlier this year, a paper on rare particle decay published in Nature listed so many co-authors–about 2,700–that the journal announced it wouldn’t have room for them all in its print editions. And it isn’t just physics. In 2003, it took 272 scientists to write up the findings of the first complete human genome–a milestone in biology–but this past June, it took 1,014 co-authors to document a minor gene sequence called the Muller F element in the fruit fly.
. . .
More than vanity is at stake. Credit on a peer-reviewed research article weighs heavily in hiring, promotion and tenure decisions. “Authorship has become such a big issue because evaluations are performed based on the number of papers people have authored,” said Dr. Larivière.
. . .
Michigan State University mathematician Jack Hetherington published a paper in 1975 on low temperature physics in Physical Review Letters with F.D.C. Willard. His colleagues only discovered that his co-author was a siamese cat several years later when Dr. Hetherington started handing out copies of the paper signed with a paw print.
In the same spirit, Shalosh B. Ekhad at Rutgers University so far has published 32 peer-reviewed papers in scientific journals with his co-author Doron Zeilberger. It turns out that Shalosh B. Ekhad is Hebrew for the model number of a personal computer used by Dr. Zeilberger. “The computer helps so much and so often,” Dr. Zeilberger said.
Not everyone takes such pranks lightly.
Immunologist Polly Matzinger at the National Institute of Allergy and Infectious Diseases named her dog, Galadriel Mirkwood, as a co-author on a paper she submitted to the Journal of Experimental Medicine. “What amazed me was that the paper went through the entire editorial process and nobody noticed,” Dr. Matzinger said. When the journal editor realized he had published work crediting an Afghan hound, he was furious, she recalled.
Physicists may be more open-minded. Sir Andre Geim, winner of the 2010 Nobel Prize in Physics, credited H.A.M.S. ter Tisha as his co-author of a 2001 paper published in the journal Physica B. Those journal editors didn’t bat an eye when his co-author was unmasked as a pet hamster. “Not a harmful joke,” said Physica editor Reyer Jochemsen at the Leiden University in the Netherlands.
“Physicists apparently, even journal editors, have a better sense of humor than the life sciences,” said Dr. Geim at the U.K.’s University of Manchester.

For the full story, see:
ROBERT LEE HOTZ. “Scientists Observe Odd Phenomenon of Multiplying Co-Authors.”The Wall Street Journal (Mon., Aug. 10, 2015): A1 & A10.
(Note: ellipses added.)
(Note: the online version of the story has the title “How Many Scientists Does It Take to Write a Paper? Apparently, Thousands.”)

Lives Lost Due to Peer Review Delays

(p. A25) In this age of instant information, medicine remains anchored in the practice of releasing new knowledge at a deliberate pace. It’s time for medical scientists to think differently about how quickly they alert the public to breakthrough findings.
Last week the National Institutes of Health announced that it had prematurely ended a large national study of how best to treat people with high blood pressure because of its exceptional results.
In this trial of more than 9,000 people age 50 and older with high blood pressure, an aggressive treatment strategy to keep systolic blood pressure below 120 was compared with a conventional one aimed at keeping it below 140. The subjects all had a high risk of heart attacks, stroke and heart failure. The N.I.H. concluded, six years into a planned eight-year study, that for these patients, pushing blood pressure down far below currently recommended levels was very beneficial.
. . .

The new information may justify a more vigorous strategy for treating blood pressure, but for now doctors and patients have been left with incomplete results, some headlines and considerable uncertainty about whether to modify current treatments.
Medicine needs to change its approach to releasing new, important information. Throughout science we are seeing more rapid modes of communication. The traditional approach was not to publish until everything was finalized and ready to be chiseled in stone. But these sorts of delays are unnecessary with the Internet. Moreover, although all the trial data has yet to be tabulated, an analysis was considered sufficiently definitive to lead independent experts to stop the multimillion-dollar study.
We believe that when there is such strong evidence for a major public health condition, there should be rapid release of the information that led to the decision to stop the trial. This approach could easily be accomplished by placing the data on the N.I.H. website or publishing the data on such platforms as bioRxiv.org, which enables fast, open review by the medical community.
. . .
Kudos to the scientists who conducted such a large, complex and important study with what will be likely to have lifesaving consequences for a condition that can be treated easily in most patients. Now the medical community needs to adopt a new approach in situations like this one to disseminate lifesaving results in a timely, comprehensive and transparent way. Lives depend on it.

For the full commentary, see:
ERIC J. TOPOL and HARLAN M. KRUMHOLZ. “Don’t Sit on Medical Breakthroughs.” The New York Times (Fri., SEPT. 17, 2015): A25.
(Note: ellipses added.)
(Note: the online version of the commentary has the date SEPT. 17, 2015, and the title “Don’t Delay News of Medical Breakthroughs.”)

Newly Found, Early Human Species, Respected Their Dead

(p. A1) [A] . . . new hominin species was announced on Thursday, [September 10, 2015] by an international team of more than 60 scientists led by Lee R. Berger, an American paleoanthropologist who is a professor of human evolution studies at the University of the Witwatersrand in Johannesburg. The species name, H. naledi, refers to the cave where the bones lay undisturbed for so long; “naledi” means “star” in the local Sesotho language.
In two papers published this week in the open-access journal eLife, the researchers said that the more than 1,550 fossil elements documenting the discovery constituted the largest sample for any hominin species in a single African site, and one of the largest anywhere in the world.
. . .
The finding, like so many others in science, was the result of pure luck followed by considerable effort.
Two local cavers, Rick Hunter and Steven Tucker, found the narrow entrance to the chamber, measuring no more than seven and a half inches wide. They were skinny enough to squeeze through, and in the light of their headlamps they saw the bones all around them. When they showed the fossil pictures to Pedro Boshoff, a caver who is also a geologist, he alerted Dr. Berger, who organized an investigation.
. . .
(p. A3) Besides introducing a new member of the prehuman family, the discovery suggests that some early hominins intentionally deposited bodies of their dead in a remote and largely inaccessible cave chamber, a behavior previously considered limited to modern humans. Some of the scientists referred to the practice as a ritualized treatment of their dead, but by “ritual” they said they meant a deliberate and repeated practice, not necessarily a kind of religious rite.
. . .
At the news conference in South Africa on Thursday, [September 10, 2015] announcing the findings, Dr. Berger said: “I do believe that the field of paleoanthropology had convinced itself, as much as 15 years ago, that we had found everything, that we were not going to make major discoveries and had this story of our origins figured out. I think many people quit exploring, thought it was safer to conduct science inside a lab or behind a computer.” What the new species Naledi says, Dr. Berger concluded, “is that there is no substitute for exploration.”

For the full story, see:
JOHN NOBLE WILFORD. “Cave Yields Addition to Human Family Tree.”The New York Times (Fri., SEPT. 11, 2015): A1 & A3.
(Note: ellipses, and bracketed word and date, added.)
(Note: the online version of the story has the date SEPT. 10, 2015, and has the title “Homo Naledi, New Species in Human Lineage, Is Found in South African Cave,”)

Those Who Use “Consensus” Argument on Global Warming, Should Endorse Genetically Modified Food

(p. B3) NAIROBI, Kenya — Mohammed Rahman doesn’t know it yet, but his small farm in central Bangladesh is globally significant. Mr. Rahman, a smallholder farmer in Krishnapur, about 60 miles northwest of the capital, Dhaka, grows eggplant on his meager acre of waterlogged land.
As we squatted in the muddy field, examining the lush green foliage and shiny purple fruits, he explained how, for the first time this season, he had been able to stop using pesticides. This was thanks to a new pest-resistant variety of eggplant supplied by the government-run Bangladesh Agricultural Research Institute.
Despite a recent hailstorm, the weather had been kind, and the new crop flourished. Productivity nearly doubled. Mr. Rahman had already harvested the small plot 10 times, he said, and sold the brinjal (eggplant’s name in the region) labeled “insecticide free” at a small premium in the local market. Now, with increased profits, he looked forward to being able to lift his family further out of poverty. I could see why this was so urgent: Half a dozen shirtless kids gathered around, clamoring for attention. They all looked stunted by malnutrition.
. . .
I, . . . , was once in [the] . . . activist camp. A lifelong environmentalist, I opposed genetically modified foods in the past. Fifteen years ago, I even participated in vandalizing field trials in Britain. Then I changed my mind.
After writing two books on the science of climate change, I decided I could no longer continue taking a pro-science position on global warming and an anti-science position on G.M.O.s.
There is an equivalent level of scientific consensus on both issues, I realized, that climate change is real and genetically modified foods are safe. I could not defend the expert consensus on one issue while opposing it on the other.

For the full commentary, see:
MARK LYNAS. “How I Got Converted to G.M.O. Food.” The New York Times, SundayReview Section (Sun., APRIL 26, 2015): 5.
(Note: ellipses, and bracketed word, added.)
(Note: the online version of the commentary has the date APRIL 24, 2015.)

“Strong-Willed Scientists Overstated the Significance of Their Studies”

The New York Times seems open to the idea that strong-willed scientists might overstate their results in science food studies. I wonder if The New York Times would be open to the same possibility in science climate studies?

(p. A19) For two generations, Americans ate fewer eggs and other animal products because policy makers told them that fat and cholesterol were bad for their health. Now both dogmas have been debunked in quick succession.
. . .
Epidemiological data can be used to suggest hypotheses but not to prove them.
Instead of accepting that this evidence was inadequate to give sound advice, strong-willed scientists overstated the significance of their studies.
Much of the epidemiological data underpinning the government’s dietary advice comes from studies run by Harvard’s school of public health. In 2011, directors of the National Institute of Statistical Sciences analyzed many of Harvard’s most important findings and found that they could not be reproduced in clinical trials.
It’s no surprise that longstanding nutritional guidelines are now being challenged.
In 2013, government advice to reduce salt intake (which remains in the current report) was contradicted by an authoritative Institute of Medicine study. And several recent meta-analyses have cast serious doubt on whether saturated fats are linked to heart disease, as the dietary guidelines continue to assert.
Uncertain science should no longer guide our nutrition policy. Indeed, cutting fat and cholesterol, as Americans have conscientiously done, may have even worsened our health.

For the full commentary, see:
NINA TEICHOLZ. “The Government’s Bad Diet Advice.” The New York Times (Sat., FEB. 21, 2015): A19.
(Note: ellipsis added.)
(Note: the online version of the commentary has the date FEB. 20, 2015.)

Entrepreneurs Creating Healthy, Tasty Meat, Without Killing Animals

(p. B2) “The next couple of years will be exciting ones,” says Joseph D. Puglisi, a Stanford University professor of structural biology who is working on meat alternatives. “We can use a broad range of plant protein sources and create a palette of textures and tastes — for example, jerky, cured meats, sausage, pork.”
“The true challenge will be to recreate more complex pieces of meat that are the pinnacle of the meat industry,” he added. “I believe that plausible, good-tasting steaks and pork loins are only a matter of time.”
Puglisi is advising Beyond Meat, a start-up that is a leader in the field, with investments from Bill Gates and both Biz Stone and Ev Williams of Twitter fame, not to mention Kleiner Perkins Caufield & Byers, the venture capital firm that backed Google and Amazon. Beyond Meat says its sales are doubling each year.
“We’re really focused on the mainstream,” said Ethan Brown, the founder of Beyond Meat, over a lunch of fake chili, meatballs and hamburgers.
. . .
“We want to create the next great American meat company,” Brown says. “That’s the dream.”
. . .
The mainstream food industry isn’t saying much publicly. But recently released documents from the American Egg Board, a quasi-governmental body, show it regarded Hampton Creek’s egg-free “Just Mayo” spread as a “major threat.” In one internal email, an Egg Board executive jokingly suggests hiring a hit man to deal with Hampton Creek.
. . .
. . . if I can still enjoy a juicy burger now and then, while boosting my health, helping the environment and avoiding the brutalizing of farm animals, hey, I’m in!

For the full commentary, see:
Nicholas Kristof. “The (Fake) Meat Revolution.” The New York Times, SundayReview Section (Sun., SEPT. 20, 2015): 11.
(Note: the online version of the commentary has the date SEPT. 19, 2015.)

New Evidence Says Scientists Must “Start from Scratch” on Computer Weather Models

“An image of Pluto’s atmosphere, backlit by the sun, captured by the New Horizons spacecraft as it zipped past the planet.” Source of caption and photo: online version of the NYT article quoted and cited below.

(p. A13) Confounding expectations, Pluto’s atmosphere has actually thickened over the last 26 years, and many planetary scientists changed their minds. Maybe the atmosphere would persist throughout Pluto’s 248-year orbit, they speculated.

Now the story appears to be changing again. New Horizons obtained a snapshot of the structure of the atmosphere by looking at distortions in radio signals sent from Earth passing through Pluto’s atmosphere.
What the new measurement “seems to have detected is a potential for the first stages of that collapse just as New Horizons arrived,” Dr. Stern said. “It would be an amazing coincidence, but there are some on our team who would say, ‘I told you so.’ ”
Even if the atmosphere is collapsing, though, the view from the night side of Pluto is, at present, spectacularly hazy. A photograph showing a silhouette of Pluto surrounded by a ring of sunlight “almost brought tears” to the atmospheric scientists, Dr. Summers said, showing sunlight scattered by small particles of haze up to 100 miles above the surface.
“This is our first peek at weather in Pluto’s atmosphere,” he said.
Computer models had suggested that the haze would float within 20 miles of the surface, where temperatures are about minus 390 degrees Fahrenheit. Instead, the haze particles formed higher, 30 to 50 miles up, where temperatures are balmier, around minus 270.
“We’re having to start from scratch to understand what we thought we knew about the atmosphere,” Dr. Summers said.

For the full story, see:
KENNETH CHANG. “Pluto’s Atmosphere Is Thinner Than Expected, but Still Looks Hazy.” The New York Times (Sat., JULY 25, 2015): A13.
(Note: ellipses added.)
(Note: the online version of the article has the date JULY 24, 2015.)

Experts Are Paid “to Sound Cocksure” Even When They Do Not Know

(p. B1) I think Philip Tetlock’s “Superforecasting: The Art and Science of Prediction,” co-written with the journalist Dan Gardner, is the most important book on decision making since Daniel Kahneman’s “Thinking, Fast and Slow.” (I helped write and edit the Kahneman book but receive no royalties from it.) Prof. Kahneman agrees. “It’s a manual to systematic thinking in the real world,” he told me. “This book shows that under the right conditions regular people are capable of improving their judgment enough to beat the professionals at their own game.”
The book is so powerful because Prof. Tetlock, a psychologist and professor of management at the University of Pennsylvania’s Wharton School, has a remarkable trove of data. He has just concluded the first stage of what he calls the Good Judgment Project, which pitted some 20,000 amateur forecasters against some of the most knowledgeable experts in the world.
The amateurs won–hands down.
. . .
(p. B7) The most careful, curious, open-minded, persistent and self-critical–as measured by a battery of psychological tests–did the best.
. . .
Most experts–like most people–“are too quick to make up their minds and too slow to change them,” he says. And experts are paid not just to be right, but to sound right: cocksure even when the evidence is sparse or ambiguous.

For the full review, see:
JASON ZWEIG. “The Trick to Making Better Forecasts.” The Wall Street Journal (Sat., Sept. 26, 2015): B1 & B7.
(Note: ellipses added.)
(Note: the online version of the review has the date Sept. 25, 2015.)

The book under review, is:
Tetlock, Philip E., and Dan Gardner. Superforecasting: The Art and Science of Prediction. New York: Crown, 2015.

“Stunned” Geophysicists Are Headed “Back to the Drawing Board”

(p. A3) Bringing the blur of a distant world into sharp focus, NASA unveiled its first intimate images of Pluto on Wednesday [July 15, 2015], revealing with startling clarity an eerie realm where frozen water rises in mountains up to 11,000 feet high.
. . .
At a briefing held Wednesday [July 15, 2015] at the Johns Hopkins Applied Physics Laboratory in Laurel, Md., mission scientists said they were stunned by what the images reveal.
“It is going to send a lot of geophysicists back to the drawing board,” said Alan Stern, the New Horizons project’s principal investigator, from the Southwest Research Institute in Boulder, Colo.

For the full story, see:
ROBERT LEE HOTZ. “Across 3 Billion Miles of Space, NASA Probe Sends Close-Ups of Pluto’s Icy Mountains.” The Wall Street Journal (Thurs., JULY 16, 2015): A3.
(Note: ellipsis, and bracketed dates, added.)
(Note: the online version of the article has the date JULY 15, 2015, has the title “NASA Releases Close-Up Pictures of Pluto and Its Largest Moon, Charon,” and has some different wording than the print version. The quote above follows the online version.)

112 Years of Spectacular Progress Started With Wilbur Wright

“New close-up images of a region near Pluto’s equator reveal a giant surprise: a range of youthful mountains.” Source of caption and photo: online version of the NYT article quoted and cited below.

(p. A1) LAUREL, Md. — The first close-up image of Pluto has revealed mountains as tall as the Rockies, and an absence of craters — discoveries that, to their delight, baffled scientists working on NASA’s New Horizons mission and provided punctuation for a journey nine and a half years in the making.

Only 112 years after the Wright Brothers were barely able to get their airplane off the ground, a machine from Earth has crossed the solar system to a small, icy world three billion miles away. The flyby on Tuesday, when New Horizons buzzed within 7,800 miles of the former ninth planet, came 50 years to the day after NASA’s Mariner 4 spacecraft made a similar first pass by Mars.

For the full story, see:
KENNETH CHANG. “Pluto’s Portrait From New Horizons: Ice Mountains and No Craters.” The New York Times (Thurs., JULY 16, 2015): A1 & A17.
(Note: the online version of the article has the date JULY 15, 2015.)