Health – Page 69 – artdiamondblog.com

Millions Die Due to Precautionary Principle Ban of DDT

(p. 248) . . . , malaria infects 300 million to 500 million people worldwide, causing 2 million deaths per year. It is debilitating to those who don’t die and leads to cyclic poverty. But in the 1950s the level of malaria was reduced by 70 percent by spraying the insecticide DDT around the insides of homes. DDT was so successful as an insecticide that farmers eagerly sprayed it by the tons on cotton fields–and the molecule’s by-products made their way into the water cycle and eventually into fat cells in animals. Biologists blamed it for a drop in reproduction rates for some predatory birds, as well as local die-offs in some fish and aquatic life species. Its use and manufacture were banned in the United States in 1972. Other countries followed suit. Without DDT spraying, however, malaria cases in Asia and Africa began to rise again to deadly pre-1950s levels. Plans to reintroduce programs for household spraying in malarial Africa were blocked by the World Bank and other aid agencies, who refused to fund them. A treaty signed in 1991 by 91 countries and the EU agreed to phase out DDT altogether. They were relying on the precautionary principle: DDT was probably bad; better safe than sorry. In fact DDT had never been shown to hurt humans, and the environmental harm from the miniscule amounts of DDT applied in homes had not been measured. But nobody could prove it did not cause harm, despite its proven ability to do good.

Source:
Kelly, Kevin. What Technology Wants. New York: Viking Adult, 2010.
(Note: ellipsis added.)

Heart Disease Affected Ancients Who Differed in Culture, Class and Diet

“Egyptologist Dr. Gomaa Abd el-Maksoud prepares the mummy Hatiay (New Kingdom, 18th Dynasty, 1550-1295 BCE) for scanning. Hatiay was found to have evidence of extensive vascular disease.” Source of caption and photo: online version of the WSJ article quoted and cited below.

(p. A4) SAN FRANCISCO–It turns out there is nothing new about heart disease.

Researchers who examined 137 mummies from four cultures spanning 4,000 years said Sunday they found robust evidence of atherosclerosis, or hardening of the arteries, challenging widely held assumptions that cardiovascular disease is largely a malady of current times.
An international research team of cardiologists, radiologists and archeologists used CT scanners to evaluate the mummies, hunting for deposits of calcium in arterial walls that are a telltale sign of hardening of the arteries that can lead to heart attacks and strokes. They found that 47, or 34%, of the mummies had such deposits, suggesting, they said, that cardiovascular disease was more common in historic times than many experts think.
. . .
The same researchers reported similar findings in 2009 from Egyptian mummies. Because those specimens were believed to have been from the upper echelons of society, the researchers surmised their calcified arteries could have developed from high-fat diets. But by expanding the research to other cultures, including Puebloans of what is now the U.S. Southwest, the researchers believe all levels of society were at risk, regardless of diet.

For the full story, see:
RON WINSLOW. “U.S. NEWS; Telltale Finding on Heart Disease.” The Wall Street Journal (Mon., March 11, 2013): A6.
(Note: the online version of the story has the date March 10, 2013.)

Federal Food Regs Drive Sharon Penner to Stop Baking for Nebraska Children

“Sharon Penner slices fresh bread, which she bakes a few times a week for Hampton, Neb., students. Penner, who has fed the town’s schoolchildren for 43 years, saw new school nutrition rules that cut many of her goodies as a sign it was time to retire. With her in the school kitchen is assistant Judy Hitzemann.” Source of caption and photo: online version of the Omaha World-Herald article quoted and cited below.

Have we gone too far when the preferences of Michelle Obama rule over the preferences of the parents of Hampton, Nebraska? And is it clear that the parents are wrong in thinking that fresh-baked bread (see photo above) and a timely pat on the shoulder (see photo below), are worth some extra calories?

(p. 1A) HAMPTON, Neb. — Blame the broccoli. Blame the mandarin oranges. Blame all their cousins, from apples to yams, for removing Mrs. Penner’s butter bars from the school lunch counter.

Then blame Mrs. Obama for removing Mrs. Penner.
So goes the thinking in this no-stoplight village of 423 people about 20 minutes northwest of York.
When the new federal school nutrition mandates went into effect this year, championed by first lady Michelle Obama, fresh-baked brownies, cookies and other sugary goodies disappeared from the school menu. And Sharon Penner, who has been feeding schoolchildren here for 43 years, decided it was a sign from above to retire.
Friday [May 17, 2013] will be the last school lunch the 70-year-old prepares for the Hampton Hawks.
Mrs. Penner is hanging up her apron.
“She is?” asked an incredulous sixth-grader named Treavar Pekar. (p. 2A) He stopped cold from scrubbing some of the six tables in the small cafeteria when I broke the news after lunch.
“NOOOOO!!!!!”
That about sums up the community response.

For the full story, see:
Grace, Erin. “Time to Hang Up Her Purple Apron.” Omaha World-Herald (FRIDAY, MAY 17, 2013): 1A-2A.
(Note: ellipses, and bracketed date, added.)
(Note: the online version of the article has the title “Grace: Hampton lunch lady ready to hang up apron.”)

“Sharon Penner with Bryce Joseph, who needed some help after dropping his breakfast tray.” Source of caption and photo: online version of the Omaha World-Herald article quoted and cited above.

Berkshire Agrees to Buy No More than 25% of DaVita, Firm Accused of Medicare Fraud

Warren Buffett’s Berkshire Hathaway has agreed to cap its ownership of DaVita Healthcare Partners at 25%. A previous entry on this blog quoted a story saying that Ted Weschler is behind Berkshire’s purchases of DaVita stock. An even earlier entry on this blog discussed accusations that DaVita Healthcare Partners has committed substantial healthcare fraud by charging the taxpayer millions of dollars for medicine that is needlessly thrown away.

(p. 2D) Berkshire agreed not to buy more than 25 percent of DaVita HealthCare Partners Inc., a national network of medical infusion clinics.
Berkshire investment manager Ted Weschler has been buying DaVita stock for Berkshire since joining the Omaha investment company last year, totaling about 14 percent of the company, Bloomberg reported.
Weschler and DaVita President Javier Rodriguez signed a “standstill agreement” last week, a document often intended to clarify whether an investor wants to acquire controlling interest in a business. Some have speculated that Berkshire wants to acquire all of DaVita’s stock, which artificially inflates the price of its shares.
DaVita legal officer Kim Rivera said Berkshire is a “supportive investor with a long-term view.”

For the full story, see:
Steve Jordon. “WARREN WATCH; At Berkshire meeting, See’s candymaker outshines Warren Buffett.” Omaha World-Herald (SUNDAY, MAY 12, 2013): 1D & 2D.

How Electricity Matters for Life

Source of book image:
http://media.npr.org/assets/bakertaylor/covers/t/the-spark-of-life/9780393078039_custom-86637e64da2201ed3081e0f26f40e0d139cbbf9d-s6-c10.jpg

(p. C9) Top-drawer scientists always are excited about their field, but many have difficulty conveying this to a general audience. Not so Frances Ashcroft. She is a distinguished physiologist at Oxford University whose work has provided crucial insight into how insulin secretion is connected to electrical activity in cells. Her research has meant that children born with one form of diabetes can control it using oral medication instead of regular and painful insulin injections.

After Ms. Ashcroft made her breakthrough in 1984, she felt as if she were “dancing in the air, shot high into the sky on the rocket of excitement with the stars exploding in vivid colours all around me,” she writes in her engaging and informative “The Spark of Life: Electricity in the Human Body.” Even today, thinking of it “sends excitement fizzing through my veins.”
Like so much else in our bodies, insulin secretion depends on crucial proteins in the cell walls that regulate the flow of ions (electrically charged atoms or molecules) between the interior of the cell and the fluids that surround it. The ions, mostly sodium, potassium and calcium, literally provide “the spark of life.” Ms. Ashcroft uses her research into cellular “ion channels” as an overture to a rich and stimulating account of how electricity and the varied ways in which animals and plants produce it explain so much of evolutionary biology.
. . .
. . . all of Ms. Ashcroft’s themes and variations represent facets of the same underlying ionic mechanism. In describing its wonders, she has produced a gem that sparkles.

For the full review, see:
WILLIAM BYNUM. “Singing the Body Electric.” The Wall Street Journal (Sat., September 29, 2012): C9.
(Note: ellipses added.)
(Note: the online version of the review has the date September 28, 2012.)

The book under review, is:
Ashcroft, Frances. The Spark of Life: Electricity in the Human Body. New York: W. W. Norton & Company, 2012.

Cooking Allowed the Toothless to Live

Source of book image: http://d.gr-assets.com/books/1344733081l/13587130.jpg

(p. C12) . . . the narrative, ragtag though it may be, is a good one and it starts with the single greatest achievement in cookware–the cooking pot. Originally made of clay, this simple invention allowed previously inedible foods to be cooked in water, a process that removed toxins, made them digestible and reduced the need for serious chewing, a deadly problem for the toothless. (Archaeologists find adult skeletons without teeth only at sites dating from after the invention of the cooking pot.)
. . .
When “Consider the Fork” turns to cultural history, Ms. Wilson’s points sometimes contradict one another. On one hand, she slyly condemns the rich throughout history and their use of cheap cooking labor. Yet she also relates how the Lebanese writer Anissa Helou remembers kibbé being made in Beirut by her mother and grandmother: They pounded the lamb in a mortar and pestle for an hour, a process described in loving terms. So is cooking labor a bedrock of family values or class exploitation?

For the full review, see:
CHRISTOPHER KIMBALL. “The World on a Plate.” The Wall Street Journal (Sat., October 6, 2012): C12.
(Note: ellipses added.)
(Note: the online version of the review has the date October 5, 2012.)

The book under review, is:
Wilson, Bee. Consider the Fork: A History of How We Cook and Eat. New York: Basic Books, 2012.

Berkshire Buys Big into DaVita, Firm Accused of Medicare Fraud

Warren Buffett’s Berkshire Hathaway apparently has a large stake in DaVita Healthcare Partners. An earlier entry on this blog discussed accusations that DaVita Healthcare Partners has committed substantial healthcare fraud by charging the taxpayer millions of dollars for medicine that is needlessly thrown away. Apparently the DaVita investment is due to Ted Weschler, one of two deputies to whom Buffett has delegated the investment of some of Berkshire’s funds.

(p. 3D) Weschler is believed to be behind Berkshire’s aggressive move into DaVita Healthcare Partners — a stock he owned when he ran his own hedge fund. Berkshire bought 10.9 million shares last year, becoming Da-Vita’s largest stakeholder with 15.7 percent of the company. DaVita provides kidney dialysis services and is seen as a consistent cash-flow generator. In November, the company closed its $4.7 billion purchase of Healthcare Partners, one of the country’s largest operators of medical groups and physician networks. DaVita shares rose more than 35 percent in the past 12 months.

For the full story, see:

MarketWatch . “Buffett was avid hunter of 6 stocks last year; Wells Fargo, GM and DirecTV top Berkshire’s list.” Omaha World-Herald (Tues., March 12, 2013): 1D & 3D.

21st Century Person Would Be Sick in Dickens’ 1850 London

“Anderson found Dickens World to be “surprisingly grisly” for a park that markets itself to children; he noted several severed heads and a gruesome performance of “Oliver Twist” in the courtyard. Here, a mannequin of Nancy from “Oliver Twist.”” Source of caption and photo: online version of the NYT article quoted and cited below.

(p. 48) . . . even if it were possible to create a lavish simulacrum of 1850s London — with its typhus and cholera and clouds of toxic corpse gas, its sewage pouring into the Thames, its (p. 49) average life span of 27 years — why would anyone want to visit? (“If a late-20th-century person were suddenly to find himself in a tavern or house of the period,” Peter Ackroyd, a Dickens biographer, has written, “he would be literally sick — sick with the smells, sick with the food, sick with the atmosphere around him.”)

For the full story, see:
SAM ANDERSON. “VOYAGES; The Pippiest Place on Earth.” The New York Times Magazine (Sun., February 7, 2012): 48-53.
(Note: ellipsis added.)
(Note: the online version of the story has the date February 7, 2012 (sic), and has the title “VOYAGES; The World of Charles Dickens, Complete With Pizza Hut.”)

Much of Human Genome Consists of Usually-Inactive Ancient Retrovirus Genes

(p. C4) Might some forms of neurological illness, such as multiple sclerosis and schizophrenia, be caused at least partly by bacteria, viruses or other parasites? A largely Danish team has recently published evidence of a strong association between multiple sclerosis and a retrovirus, together with hints that a gene called TRIM5, which is used by cells to fight viruses, is especially active in people with MS.
. . .
The virus implicated in multiple sclerosis is called HERV-Fc1, a bizarre beast called an “endogenous” retrovirus. What this means is that its genes are part of the human genome. For millions of years, they have been integrated into our own DNA and passed on by normal heredity. It was one of the shocks of genomic science to find that the human genome contains more retroviral than “human” genes: some 5% to 8% of the entire genome.
Normally, the genes of endogenous retroviruses remain dormant, but–a bit like a computer virus that springs into action on a trigger–something wakes them up sometimes, and actual viruses are made from them, which then infect other cells in the body. The Danish scientists suggest that this is what happens in multiple sclerosis. Bjørn Nexø of Aarhus University writes that “retroviral infections often develop into running battles between the immune system and virus, with the virus mutating repeatedly to avoid the immune system, and the immune system repeatedly catching up. One can see the episodic nature of multiple sclerosis as such a running battle.”

For the full commentary, see:
MATT RIDLEY. “MIND & MATTER; The Good News About the Virus in Your Genes.” The Wall Street Journal (Sat., March 10, 2012): C4.
(Note: ellipsis added.)
(Note: the online version of the commentary has the date March 9, 2012.)

Stem-Cell Researchers Developing Experimental Personalized Medicine

(p. C4) Last month a team at Johns Hopkins University and the Sloan-Kettering Institute for Cancer Research, using a version of Dr. Yamanaka’s technique, successfully grew nerve cells from a patient suffering from a rare disease called Riley-Day syndrome, which is linked to early mortality, seizures and other symptoms and caused by a fault in one gene.
But the purpose was not to put these cells back into the patient. Instead the scientists tested 6,912 chemical compounds on the cells to see if they could find one that “rescued” the “expression” of the gene: that is to say, caused it to produce the protein it is supposed to produce. One of the compounds worked, inducing the gene to be actively transcribed by the cell.
In the not-very-distant future, when something is going wrong in one of your organs, one treatment may be to create some stem cells from your body in the laboratory, turn them into cells of that organ, or even rudimentary structures, and then subject them to experimental treatments to see if something cures the problem. The goal of personalized medicine, in other words, may be reached by stem-cell researchers before it’s reached by geneticists.

For the full commentary, see:
MATT RIDLEY. “MIND & MATTER; Stem-Cell Cures Without the Controversy.” The Wall Street Journal (Sat., December 8, 2012): C4.
(Note: the online version of the commentary has the date December 7, 2012.)

Longer Life Spans “Allowed More Time to Invent New Tools”

(p. 33) The primary long-term consequence of . . . slightly better nutrition was a steady increase in longevity. Anthropologist Rachel Caspari studied the dental fossils of 768 hominin individuals in Europe, Asia, and Africa, dated from 5 million years ago until the great leap. She determined that a “dramatic increase in longevity in the modern humans” began about 50,000 years ago. Increasing longevity allowed grandparenting, creating what is called the grandmother effect: In a virtuous circle, via the communication of grandparents, ever more powerful innovations carried forward were able to lengthen life spans further, which allowed more time to invent new tools, which increased population. Not only that: Increased longevity “provide[d] a selective advantage promoting further population increase,” because a higher density of humans increased the rate and influence of innovations, which contributed to increased populations. Caspari claims that the most fundamental biological factor that underlies the behavioral innovations of modernity maybe the increase in adult survivorship. It is no coincidence that increased longevity is the most measurable consequence of the acquisition of technology. It is also the most consequential.

Source:
Kelly, Kevin. What Technology Wants. New York: Viking Adult, 2010.
(Note: ellipsis added; bracketed “d” in Kelly’s original.)