“The Data Run Counter to Your Anecdotes”

(p. A13) “Shattered,” by campaign reporters Jonathan Allen and Amie Parnes, narrates the petty bickering, foolish reasoning and sheer arrogance of a campaign that was never the sure thing that its leader and top staffers assumed. The authors, in a mostly successful attempt to get their sources to talk candidly, promised them that they wouldn’t be identified.
. . .
The juicy quotes would mean more if they were on the record, but mostly it works: You can’t pinpoint the identity of any one “top aide” or “close Hillary ally,” but the authors’ language leads you to believe they include the most senior Clinton advisers–Mr. Podesta, longtime Clinton confidante Huma Abedin, campaign manager Robby Mook, speechwriter Dan Schwerin, policy adviser Jake Sullivan –and probably the candidate herself.
. . .
Successful politicians must have a tacit sense of what voters want to hear and how they might be persuaded. Mrs. Clinton–in stark contrast to her husband–was never interested in that component of campaigning. You got the feeling she didn’t like people all that much.
Mr. Mook’s scientific “model” of how the campaign should run emphasized demographics, constituents’ voting histories, regional electoral patterns, and so on. When staffers objected to his directives, the authors record, the response was always the same: “The data,” as Mr. Mook at one point put it to former President Bill Clinton, “run counter to your anecdotes.”

For the full review, see:
Barton Swaim. “BOOKSHELF; Hillary the Unready.” The Wall Street Journal (Tues., April 18, 2017): A13.
(Note: ellipses added.)
(Note: the online version of the review has the date April 17, 2017, and has the title “BOOKSHELF; How Hillary Lost the White House.”)

The book under review, is:
Allen, Jonathan, and Amie Parnes. Shattered: Inside Hillary Clinton’s Doomed Campaign. New York: Crown, 2017.

94-Year-Old Applies for Patent on Slow-Hunch Solid State Battery

(p. 7) In 1946, a 23-year-old Army veteran named John Goodenough headed to the University of Chicago with a dream of studying physics. When he arrived, a professor warned him that he was already too old to succeed in the field.
Recently, Dr. Goodenough recounted that story for me and then laughed uproariously. He ignored the professor’s advice and today, at 94, has just set the tech industry abuzz with his blazing creativity. He and his team at the University of Texas at Austin filed a patent application on a new kind of battery that, if it works as promised, would be so cheap, lightweight and safe that it would revolutionize electric cars and kill off petroleum-fueled vehicles. His announcement has caused a stir, in part, because Dr. Goodenough has done it before. In 1980, at age 57, he coinvented the lithium-ion battery that shrank power into a tiny package.
We tend to assume that creativity wanes with age. But Dr. Goodenough’s story suggests that some people actually become more creative as they grow older. Unfortunately, those late-blooming geniuses have to contend with powerful biases against them.
. . .
Years ago, he decided to create a solid battery that would be safer. Of course, in a perfect world, the “solid-state” battery would also be low-cost and lightweight. Then, two years ago, he discovered the work of Maria Helena Braga, a Portuguese physicist who, with the help of a colleague, had created a kind of glass that can replace liquid electrolytes inside batteries.
Dr. Goodenough persuaded Dr. Braga to move to Austin and join his lab. “We did some experiments to make sure the glass was dry. Then we were off to the races,” he said.
Some of his colleagues were dubious that he could pull it off. But Dr. Goodenough was not dissuaded. “I’m old enough to know you can’t close your mind to new ideas. You have to test out every possibility if you want something new.”
When I asked him about his late-life success, he said: “Some of us are turtles; we crawl and struggle along, and we haven’t maybe figured it out by the time we’re 30. But the turtles have to keep on walking.” This crawl through life can be advantageous, he pointed out, particularly if you meander around through different fields, picking up clues as you go along. Dr. Goodenough started in physics and hopped sideways into chemistry and materials science, while also keeping his eye on the social and political trends that could drive a green economy. “You have to draw on a fair amount of experience in order to be able to put ideas together,” he said.

For the full commentary, see:
Kennedy, Pagan. “To Be a Genius, Think Like a 94-Year-Old.” The New York Times, SundayReview Section (Sun., APRIL 9, 2017): 7.
(Note: ellipsis added.)
(Note: the online version of the commentary has the date APRIL 7, 2017.)

Since 1880 North America Is Warmer by One and a Half Degrees Fahrenheit

(p. A23) Anyone who has read the 2014 report of the Intergovernmental Panel on Climate Change knows that, while the modest (0.85 degrees Celsius, or about 1.5 degrees Fahrenheit) warming of the earth since 1880 is indisputable, as is the human influence on that warming, much else that passes as accepted fact is really a matter of probabilities. That’s especially true of the sophisticated but fallible models and simulations by which scientists attempt to peer into the climate future. To say this isn’t to deny science. It’s to acknowledge it honestly.

For the full commentary, see:
Stephens, Bret. “Climate of Complete Certainty.” The New York Times (Sat., APRIL 29, 2017): A23.
(Note: the online version of the commentary has the date APRIL 28, 2017.)

Kenneth Arrow Had Broad Knowledge Beyond Economics

(p. A21) Professor Arrow was widely hailed as a polymath, possessing prodigious knowledge of subjects far removed from economics. Eric Maskin, a Harvard economist and fellow Nobel winner, told of a good-natured conspiracy waged by junior faculty to get the better of Professor Arrow, even if artificially. They all agreed to study the breeding habits of gray whales — a suitably abstruse topic — and gathered at an appointed date at a place where Professor Arrow would be sure to visit.
When, as expected, he showed up, they were talking out loud about the theory by a marine biologist — last name, Turner — which purported to explain how gray whales found the same breeding spot year after year. As Professor Maskin recounted the story, “Ken was silent,” and his junior colleagues amused themselves that they had for once bested their formidable professor.
Well, not so fast.
Before leaving, Professor Arrow muttered, “But I thought that Turner’s theory was entirely discredited by Spencer, who showed that the hypothesized homing mechanism couldn’t possibly work.”

For the full obituary, see:
MICHAEL M. WEINSTEIN. “Kenneth Arrow, Influential Economist and Nobel Laureate, Is Dead at 95.” The New York Times (Weds., FEB. 22, 2017): A21.
(Note: the online version of the obituary has the date FEB. 21, 2017, and has the title “Kenneth Arrow, Nobel-Winning Economist Whose Influence Spanned Decades, Dies at 95.”)

Trump Victory Undercut Faith in Big Data

(p. B1) It was a rough night for number crunchers. And for the faith that people in every field — business, politics, sports and academia — have increasingly placed in the power of data.
Donald J. Trump’s victory ran counter to almost every major forecast — undercutting the belief that analyzing reams of data can accurately predict events. Voters demonstrated how much predictive analytics, and election forecasting in particular, remains a young science: . . .
. . .
(p. B5) This week’s failed election predictions suggest that the rush to exploit data may have outstripped the ability to recognize its limits.
. . .
Beyond election night, there are broader lessons that raise questions about the rush to embrace data-driven decision-making across the economy and society.
The enthusiasm for big data has been fueled by the success stories of Silicon Valley giants born on the internet, like Google, Amazon and Facebook. The digital powerhouses harvest vast amounts of user data using clever software for search, social networks and online commerce. Data is the fuel, and algorithms borrowed from the tool kit of artificial intelligence, notably machine learning, are the engine.
. . .
The danger, data experts say, lies in trusting the data analysis too much without grasping its limitations and the potentially flawed assumptions of the people who build predictive models.

For the full story, see:
STEVE LOHR and NATASHA SINGER. “How Data Failed Us in Calling an Election.” The New York Times (Sat., NOV. 10, 2016): B1 & B5.
(Note: ellipses added.)

Double-Blind Trials Are Not the Only Source of Sound Knowledge

(p. 1) . . . while all doctors agree about the importance of gauging the quality of evidence, many feel that a hierarchy of methods is simplistic. As the doctor Mark Tonelli has argued, distinct forms of knowledge can’t be judged by the same standards: what a patient prefers on the basis of personal experience; what a doctor thinks on the basis of clinical experience; and what clinical research has discovered — each of these is valuable in its own way. While scientists concur that randomized trials are ideal for evaluating the average effects of treatments, such precision isn’t necessary when the benefits are obvious or clear from other data.
Clinical expertise and rigorous evaluation also differ in their utility at different stages of scientific inquiry. For discovery and explanation, as the clinical epidemiologist Jan Vandenbroucke has argued, practitioners’ instincts, observations and case studies are most useful, whereas randomized controlled trials are least useful. Expertise and systematic evaluation are partners, not rivals.
Distrusting expertise makes it easy to confuse an absence of randomized evaluations with an absence of knowledge. And this leads to the false belief that knowledge of what works in social policy, education or fighting terrorism can come only from randomized evaluations. But by that logic (as a spoof scientific article claimed), we don’t know if parachutes really work because we have no randomized controlled trials of them.

For the full commentary, see:
PAGAN KENNEDY. “The Thin Gene.” The New York Times, SundayReview Section (Sun., NOV. 27, 2016): 1 & 6.
(Note: ellipsis added.)
(Note: the online version of the commentary has the date NOV. 25, 2016.)

The academic article calling for double-blind randomized trials to establish the efficacy of parachutes, is:
Smith, Gordon C. S., and Jill P. Pell. “Parachute Use to Prevent Death and Major Trauma Related to Gravitational Challenge: Systematic Review of Randomised Controlled Trials.” BMJ 327, no. 7429 (Dec. 18, 2003): 1459-61.

Science Can Learn Much from Outliers “Who Are Naturally Different”

(p. 1) Abby Solomon suffers from a one-in-a-billion genetic syndrome: After just about an hour without food, she begins to starve. She sleeps in snatches. In her dreams she gorges on French fries. But as soon as she wakes up and nibbles a few bites, she feels full, so she ends up consuming very few calories. At 5 feet 10 inches tall, she weighs 99 pounds.
Now 21 years old, she is one of the few people in the world to survive into adulthood with neonatal progeroid syndrome, a condition that results from damage to the FBN1 gene.
. . .
(p. 6) Dr. Chopra told me that, as far as medical science is concerned, Abby Solomon is worth thousands of the rest of us.
. . .
“Nothing comes close to starting with people who are naturally different,” he said. This is why he searches out patients at the extreme ends of the spectrum — those who are wired to weigh 80 pounds or 380 pounds. He said, “We have the opportunity to help a bigger swath of humanity when we learn from these outliers.”
In 2013, after hearing about Ms. Solomon’s unusual condition from another patient, he asked her to visit his clinic. Ms. Solomon warned him that she would be able to carry on a conversation for only 15 minutes before she needed to snack on chips or a cookie. That remark inspired a revelation. Dr. Chopra realized that “she had to eat small, sugary meals all day to stay alive, because her body was constantly running out of glucose,” he said.
The clue led Dr. Chopra and his colleagues to their discovery of the blood-sugar-regulating hormone, which they named asprosin. Ms. Solomon’s natural asprosin deficiency keeps her on the brink of starvation, but Dr. Chopra’s hope is that an artificial compound that blocks asprosin could be used as a treatment for obesity. He and his team have already tested such a compound on mice, and found that it can reverse insulin resistance and weight gain.

For the full commentary, see:
PAGAN KENNEDY. “The Thin Gene.” The New York Times, SundayReview Section (Sun., NOV. 27, 2016): 1 & 6.
(Note: ellipses added.)
(Note: the online version of the commentary has the date NOV. 25, 2016.)

Jane Jacobs Studied the “Mess of Everyday Life”

(p. C6) The decidedly unpredictable and unscientific mess of everyday life was the passion of the urban theorist Jane Jacobs. For her, studying the street and the city was the key to understanding how things work. Robert Kanigel’s “Eyes on the Street: The Life of Jane Jacobs” has taken a place on my bookshelf right next to Robert Caro’s landmark biography of her nemesis, Robert Moses.

For Bierut’s full book recommendations, see:
Michael Bierut. “12 Months of Reading.” The Wall Street Journal (Sat., December 10, 2016): C6.
(Note: the online version of the review has the date Dec. 7, 2016, and has the title “Michael Bierut on Jane Jacobs.”)

The book recommended, is:
Kanigel, Robert. Eyes on the Street: The Life of Jane Jacobs. New York: Alfred A. Knopf, 2016.

“Celebration of Big Data” Becomes “Funeral”

(p. B8) DENVER — At the governor’s mansion here on Friday [November 11, 2016], past the columned entryway and the French chandeliers, Emmy Ruiz placed a hand on the shoulder of a fellow Hillary Clinton operative. “It’s like we’re at a funeral,” said Ms. Ruiz, dressed — perhaps coincidentally — in black.
Just days after Donald J. Trump’s surprise presidential victory, the nation’s professional political forecasters and persuaders — the pollsters, the ad creators, the campaign strategists — gathered in Denver for their annual convention. It was supposed to be a celebration of big data and strategic wizardry for a multibillion-dollar industry that has spent nearly a century packaging political candidates.
Instead, the conference of the International Association of Political Consultants felt like a therapy session for a business in psychological free fall.

For the full story, see:
JULIE TURKEWITZ. “At Conference, Political Consultants Wonder Where They Went Wrong.” The New York Times (Tues., NOV. 15, 2016): B8.
(Note: bracketed date added.)
(Note: the online version of the story has the date NOV. 14, 2016.)

Economist Removed from Plane for Scribbling Math

The seatmate was wrong to think the scribbling was Arabic, but was right to be alarmed.

(p. A13) In May [2016], an Italian economist from the University of Pennsylvania was removed from an American Airlines flight in Philadelphia after his seatmate became alarmed, thinking that the math he was scribbling on a piece of paper was Arabic, The Washington Post reported.

For the full story, see:
CHRISTINE HAUSER. “American Airlines Orders 2 Muslim American Women Off a Long-Delayed Flight.” The New York Times (Sat., AUG. 5, 2016): A13.
(Note: bracketed year added.)
(Note: the online version of the story has the date AUG. 5, 2016, and has the title “2 Muslim American Women Ordered Off American Airlines Flight.”)

Many Discoveries Take a Long Time Because “No One Really Looked”

Periods are a strange phenomenon. We don’t know why humans have them, or, to look at it another way, why most other animals don’t. Scientists say only 1.5 percent of mammal species have periods, and most of those are primates like us. The ranks of the menstrually afflicted grew a little bit recently, as researchers learned that female spiny mice have periods, too. They shared their findings on the bioRxiv preprint server.
. . .
Why did it take scientists so long to notice that these curious creatures were part of the period posse? “The answer, as with many discoveries in science, is that no one really looked,” said Hayley Dickinson, a reproductive physiologist and long-time spiny rat researcher at the University of Monash. “Everyone knew that rodents didn’t menstruate.”

For the full story, see:
Nowogrodzki, Anna. “First Rodent Found with a Humanlike Menstrual Cycle.” Nature (Fri., June 10, 2016).
(Note: ellipsis added.)

The preprint of the research mentioned above is:
Bellofiore, Nadia, Stacey J. Ellery, Jared Mamrot, David W. Walker, Peter Temple-Smith, and Hayley Dickinson. “First Evidence of a Menstruating Rodent: The Spiny Mouse (Acomys Cahirinus).” bioRxiv (June 3, 2016).