A Few More Months of Life Is Front Page News for Pancreatic Cancer Patients

For those with late stage pancreatic cancer, half live less than a year and half live longer than a year, according to the front page WSJ article quoted below. But the article seems to be celebrating a patient who has survived 17 months on a new drug. The patient has a feeling, perhaps because of a lesion that they radiated, that the drug may stop working soon.

So let’s say that without the drug she might have expected roughly a year of life, and now with the drug she has gotten roughly 17 months of life. Sure 17 months is better than 12 months.

But are our expectations so low and our cancer progress so slow, that an extra five months of life is front-page news?

(p. A1) Pranathi Perati was running out of time to treat her stage-four pancreatic cancer when she found out she would get another shot: a clinical trial testing a new experimental drug.

Perati’s odds were slim—3% of late-stage pancreatic-cancer patients are still alive after five years. And half of all pancreatic-cancer patients live for less than a year after their diagnosis. For Perati, the drug, daraxonrasib from Revolution Medicines, has helped keep her alive for 17 months and counting.

. . .

(p. A4) The pill has given her some fatigue and mouth ulcers, but she feels better than she did with chemo. A lesion in her lung started progressing this past winter and was radiated, but her disease has been stable otherwise.

“Seventeen months is a lot of good time to buy,” she said. Still, Perati worries that her time on the drug might soon run out. She has started looking for more options. Her son is set to graduate high school this summer.

For the full story see:

Brianna Abbott. “Treatments Offer Hope On Pancreatic Cancer.” The Wall Street Journal (Saturday, March 1, 2025): A1 & A4.

(Note: ellipsis added.)

(Note: the online version of the story has the date February 28, 2025, and has the title “New Treatments Give Hope to Patients With One of the Deadliest Cancers.”)

Nicholas Wade Highlighted That Early Email to Fauci Supported Lab-Leak Origin of Covid-19

Distinguished science journalist Nicholas Wade was one of the first and the few to early-on risk being canceled by providing evidence in favor of the lab-leak origin of Covid-19.

(p. A13) They told the world that the Covid-19 virus clearly couldn’t have been manipulated in the laboratory. But what they actually thought at first sight was that it had been.

The letter from five virologists published in Nature Medicine on March 17, 2020, was the single most influential statement in capturing the public narrative about the origin of SARS-CoV-2. Here was an authoritative statement from leading experts assuring the public that in terms of the virus’s origin “we do not believe that any type of laboratory-based scenario is plausible.”

But that’s the exact opposite of what these experts thought after taking their first look at the virus. A large batch of emails exchanged with Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, was made available this week to BuzzFeed and the Washington Post under the Freedom of Information Act. For the most part the emails concern meeting arrangements or messages from cranks and have been redacted of any meaningful information. But one significant email escaped the censor’s black marker.

On Jan. 31, 2020, shortly after the SARS-CoV-2 genome had been decoded, Kristian Andersen, the five virologists’ leader, emailed Dr. Fauci that there were “unusual features” in the virus. These took up only a small percentage of the genome, so that “one has to look really closely at all the sequences to see that some of the features (potentially) look engineered.”

Mr. Andersen went on to note that he and his team “all find the genome inconsistent with expectations from evolutionary theory.” It isn’t clear exactly what he meant by this striking phrase. But anything inconsistent with an evolutionary origin has to be man-made.

For the full commentary see:

Nicholas Wade. “Fauci Email Bolsters the Lab-Leak Theory.” The Wall Street Journal (Monday, June 5, 2021 [sic]): A13.

(Note: the online version of the commentary has the date June 4, 2021 [sic], and has the same title as the print version.)

Impact of Weight Loss Drugs Underlines the Importance of Serendipity and Medical Entrepreneurship

The story of the creation of the weight loss drugs involves a fair amount of serendipity and medical entrepreneurship. A case has been made that we would have had these drugs 25 years sooner if Pfizer had not abandoned the development of their version due to the dauntingly huge costs of drug development. Recall that the largest component of those huge costs are the mandated Phase 3 randomized double-blind clinical trials.

Almost everyone now views these drugs as a major medical advance. The question is: how big? According to the reviewer quoted below, Dr. Eric Topol speculates: very big indeed. He raises the possibility that to improve lifespan and healthspan eventually most of us will be on one of these drugs.

If so then the weight loss drugs will be even more compelling examples of the importance of regulating so as to allow entrepreneurs to take quick advantage of serendipity. How many lives were lost that could have been saved, how much suffering was experienced that could have been avoided, if over-regulation by the F.D.A. had not delayed the availability of these drugs by 25 years?

(p. A13) More than half of American adults suffer from at least one chronic illness—most commonly diabetes, heart disease, cancer or neurodegeneration. By age 65, 80% are afflicted with two or more conditions. Among those fortunate enough to reach 80, it’s rare to find anyone who has arrived unscathed. In 2008 a group of scientists at the Scripps Research Institute in San Diego set out to recruit 1,400 of these healthy souls—known as the Wellderly—to figure out how they managed it.

Led by the cardiologist Eric Topol, the researchers hoped to identify the genetic factors associated with healthy aging. To their surprise, they found little in the DNA that stood out. They did, however, notice several striking traits. Compared with their peers, the disease-free subjects were generally thinner, exercised more frequently and seemed “remarkably upbeat,” often with rich social lives. These observations encouraged the research team to think about longevity (years of life) and healthspan (years of health) more broadly. In “Super Agers” Dr. Topol shares the results of this intellectual exploration.

. . .

Expensive new weight-loss drugs like Ozempic and Zepbound, Dr. Topol writes, have “extraordinary potential to promote health span.” In addition to stanching appetite, these drugs also seem to rapidly reduce harmful inflammation—an effect that “precedes and is independent of weight loss.” In the future, the author believes it’s “conceivable that most people will be taking” such medications, . . .

For the full review see:

David A. Shaywitz. “Bookshelf; Living the Good Life.” The Wall Street Journal (Wednesday, May 7, 2025): A13.

(Note: ellipses added.)

(Note: the online version of the review has the date May 6, 2025, and has the title “Bookshelf; ‘Super Agers’: Living the Good Life.”)

The book under review is:

Topol, Eric. Super Agers: An Evidence-Based Approach to Longevity. New York: Simon & Schuster, 2025.

Trump Is a Change Agent Because He Can Take the Ill Will of the Stagnationists

In an earlier blog entry I pondered Charlie Munger’s sage analysis that agents of change must often be willing to take the “ill will” aimed at them from the stagnationists who benefit from stasis. The stagnationists may be corrupt, or incompetent, or simply lack the imagination or the energy to do something in a better way.

Agents of change are scarce because most of us care a lot about what other people think of us. We experience psychic stress if we are systematically stigmatized, or even just ignored. Donald Trump may be capable of making major changes because, through temperament or resolve, he has found a way to shut out the psychic stress; a way to take the ill will.

Kessler’s commentary, quoted below, was published early in the pandemic, on Feb. 10, 2020. At that point Kessler believed that Trump’s success with the economy would get Trump re-elected. But as the months of 2020 rolled on, the pandemic increasingly hurt Trump’s prospects; hence the source of the pandemic still matters a lot, and whether the vaccine was intentionally delayed a few weeks, to release it just after the election, also still matters a lot.

A key question is whether Trump still has the core “agenda of tax cuts, deregulation and originalist judges” that Kessler believed was the Trump core agenda in 2016.

I hope yes, but fear no. In 2025 are tariffs and industrial policy part of the “distraction” (aka “MacGuffin”) Kessler posits, or are they part of Trump’s core agenda?

(p. A15) Is he a disease or a cure? Like him or hate him, there’s tons of spilled ink trying to assess President Trump’s governing style. To me, the key to understanding Trumpism is remembering why he was elected.

What do I mean? Voters chose Donald Trump as an antidote to the growing inflammation caused by the (OK, deep breath . . .) prosperity-crushing, speech-inhibiting, nanny state-building, carbon-obsessing, patriarchy-bashing, implicit bias-accusing, tokey-wokey, globalist, swamp-creature governing class—all perfectly embodied by the Democrats’ 2016 nominee. On taking office, Mr. Trump proceeded to hire smart people and create a massive diversion (tweets, border walls, tariffs) as a smokescreen to let them implement an agenda of tax cuts, deregulation and originalist judges.

Those reforms have left the market free to do its magic and got the economy grooving like it’s 1999. The daily Trump hurricane—like the commotion over the Chiefs from Kansas—makes the media focus on the all-powerful wizard while ignoring the policy makers behind the curtain.

Alfred Hitchcock called this kind of distraction a “MacGuffin”—something that moves the plot along and provides motivation for the characters, but is itself unimportant, insignificant or irrelevant. It can be a kind of sleight of hand, a distraction, and Mr. Trump uses his own public persona as a MacGuffin in precisely that way. The mobs decked in “Resist” jewelry fall for it every time.

For example, Sen. Bernie Sanders used his remarks during the Senate impeachment trial to point out that the media had documented some 16,200 alleged lies by President Trump. The MacGuffin worked! Mr. Sanders and his peers are focused on the president’s words, while most voters see the real plot unfolding in America—millions of jobs and rising wages.

The president’s success comes from his ability to shrug off critics.  . . .  Rather than cower at the criticism he faces from the mobs, he probably smirks and thinks to himself, “Yeah, I don’t believe in that” and tweets away.

That’s the only reaction that can withstand today’s far left, which has become increasingly self-righteous.

For the full commentary see:

Andy Kessler. “President Donald J. MacGuffin.” The Wall Street Journal (Monday, February 10, 2020 [sic]): A17.

(Note: ellipses added.)

(Note: the online version of the commentary has the date February 9, 2020 [sic], and has the same title as the print version.)

Gans Showed That Urban Working-Class Enclaves, and Modern Suburban Housing Developments, Can Contain Vibrant Communities

In my Openness book I argue that, especially in America and Europe, life has generally gotten better in the last couple of hundred years.

Some critics argue, to the contrary, that modern suburban housing developments are boring, conformist locations lacking a sense of community and cultural vibrancy. They then use this argument to advocate that government urban planners adopt regulatory and subsidy policies to “infill the urban core,” i.e., force suburbanites to live downtown.

Herbert J. Gans, quoted below, refuted the critics.

(p. B11) Herbert J. Gans, an eminent sociologist who studied the communities and cultural bastions of America up close and shattered popular myths about urban and suburban life, poverty, ethnic groups and the news media, died on Monday [April 21, 2025] at his home in Manhattan. He was 97.

. . .

His findings were often surprising. For his first book, “The Urban Villagers: Groups and Class in the Life of Italian-Americans” (1962), he immersed himself in the life of Boston’s working-class West End. The area was later bulldozed for “slum clearance,” and he lamented the destruction of a vibrant community. A half-century later, the book still stood as a classic statement against indiscriminate urban renewal.

Similarly, Dr. Gans challenged conventional wisdom about postwar suburbia in “The Levittowners” (1967). For more than two years, he lived in Levittown, N.J., later renamed Willingboro, and concluded that the residents had strong social, economic and political commitments, and that notions of suburbanites as conformist, anxious, bored, cultureless, insecure social climbers were wrong.

For the full obituary, see:

Robert D. McFadden. “Herbert J. Gans, 97, Who Explored American Society Up Close, Dies.” The New York Times (Thursday, April 24, 2025): B11.

(Note: ellipsis, and bracketed date, added.)

(Note: the online version of the obituary was updated April 23, 2025, and has the title “Herbert J. Gans, 97, Dies; Upended Myths of Urban and Suburban Life.”)

Gans’s books mentioned in the passages quoted above, are:

Gans, ‎Herbert J. The Levittowners: Ways of Life and Politics in a New Suburban Community. New York: Columbia University Press, 1967.

Gans, ‎Herbert J. The Urban Villagers: Groups and Class in the Life of Italian-Americans. Glencoe, IL: The Free Press of Glencoe, 1962.

My book mentioned in my initial comments is:

Diamond, Arthur M., Jr. Openness to Creative Destruction: Sustaining Innovative Dynamism. New York: Oxford University Press, 2019.

Stop Subsidizing Corn Growing to Reduce Corn Syrup Consumption and Make America Healthy Again

In a recent blog entry I discussed how consumption of corn syrup may increase obesity and how government subsidies to corn growing and quotas on the import of sugar, lead to increased consumption of corn syrup. In the entry below, I document brief comments by Robert F. Kennedy, Jr. on corn syrup.

(p. A15) In my speech endorsing Donald Trump, I said we need to love our kids more than we hate each other. That means coming together to address common problems, and few are more urgent than the chronic-disease crisis. Americans are becoming sicker, beset by illnesses that our medical system isn’t addressing effectively.

. . .

Mr. Trump has made reforming broken institutions a cornerstone of his political life. He has become the voice of countless Americans who have been let down by our elites. He could unite the country by making it his priority to make America healthy again. Here are some specific policy ideas:

. . .

• Reform crop subsidies. They make corn, soybeans and wheat artificially cheap, so those crops end up in many processed forms. Soybean oil in the 1990s became a major source of American calories, and high-fructose corn syrup is everywhere.

For the full commentary see:

Robert F. Kennedy Jr. “Trump Can Make America Healthy Again.” The Wall Street Journal (Friday, Sept. 6, 2024): A15.

(Note: ellipses added.)

(Note: the online version of the commentary has the date September 5, 2024, and has the same title as the print version.)

Not Every Fluoride Worry Is Anti-Science Misinformation

Emily Oster is an economist who believes that ordinary citizens are not uniformly stupid and ill-informed. Maybe they even have rights. So she suggests the public health authorities stop condescending and shouting commands and start offering the public nuanced information about varying levels of certainty and risk.

(p. 4) Robert F. Kennedy Jr. said this month that the new Trump administration would recommend removing fluoride from public water supplies. The suggestion that fluoride was unsafe was immediately criticized by many public health experts as anti-science misinformation.

But there’s a real danger to painting everyone with concerns about fluoride as a conspiracy theorist. It’s not that we should remove fluoride from tap water (we shouldn’t), but fluoride is a complex topic, and glossing over that complexity — as public health experts and agencies often do — leaves people understandably skeptical.

Public health agencies typically tell people what to do and what not to do, but they don’t regularly explain why — or why people might hear something different from others. They also often fail to prioritize. In the end, advice for a range of topics is delivered with the same level of confidence and, seemingly, the same level of urgency. The problem is that when people find one piece of guidance is overstated, they may begin to distrust everything.

. . .

Deservedly or not, public health authorities lost a lot of trust, especially during the pandemic, and they have struggled to get it back. This has left an opening for others. The reaction from public health officials often seems to be to yell the same thing, only more loudly. This isn’t working.

For the full commentary see:

Emily Oster. “How to Talk About Fluoride, Vaccines and Raw Milk.” The New York Times, SundayOpinion Section (Sun., November 17, 2024): 4.

(Note: ellipsis added.)

(Note: the online version of the commentary has the date Nov. 13, 2024, and has the title “There’s a Better Way to Talk About Fluoride, Vaccines and Raw Milk.”)

Medical Entrepreneur Fired for Nimbly Pivoting to Get Job Done

Back in early 2021, the Moderna vaccine was not yet widely available. Protocols mandated who could get the scarce shots, prioritizing health care workers, senior citizens, and those with severe diseases. Each vial contained enough for 10 doses, but the doses had to be given with six hours, before the vaccine spoiled. On Dec. 29 Dr. Hasan Gokal, a Pakistani immigrant, worked at the county’s first vaccination event, set up for health care workers. Near the end of the scheduled event a health care worker showed up and a nurse punctured a new vial to give the worker the shot.

Now, what to do with the remaining nine doses? He got on the phone and drove around seeking and finding several senior citizens who wanted the vaccine. Exhausted with a half-hour until the vaccine expired, he gave the final dose to his wife, who had pulmonary sarcoidosis, which was indicated in the protocols as a qualification for the vaccine.

Dr. Gokal’s supervisor and the director of human resources then fired Dr. Gokal:

The officials maintained that he had violated protocol and should have returned the remaining doses to the office or thrown them away, the doctor recalled. He also said that one of the officials startled him by questioning the lack of “equity” among those he had vaccinated.

“Are you suggesting that there were too many Indian names in that group?” Dr. Gokal said he asked.

Exactly, he said he was told. (Barry 2021, p. A5)

A couple of weeks later, the county district attorney charged Dr. Gokal with theft of doses of the vaccine.

Dr. Gokal acted as a medical entrepreneur. His job was to save lives by administering the vaccine. He nimbly pivoted in a difficult situation. For that he was punished–fired and charged with a crime.

The growing promulgation and enforcement of protocols limit physicians from acting as mission-oriented entrepreneurs. They are limited in their use of judgement based on their own experiences, they are limited in innovating, and sometimes they are even limited in using all of a scarce vaccine. These limits may be part of the reason that so many physicians today experience frustration and burn-out.

[As of the time of the writing of the NYT article cited below, Dr. Gokal remained fired from his job, and still was in legal jeopardy.]

My source for the facts of Dr. Gokal’s case, is the NYT article:

Dan Barry. “Racing the Clock, a Doctor Gave Out the Vaccine.” The New York Times (Thurs., February 11, 2021 [sic]): A1 & A5.

(Note: the online version of the NYT article was updated June 23, 2023 [sic], and has the title “The Vaccine Had to Be Used. He Used It. He Was Fired.”)

NBER Study Asserts That High-Risk Medicare Beneficiaries Are Clueless

I have looked at the National Bureau of Economic Research (NBER) paper mentioned below, and suspect (and hope) that its key findings are wrong. I do not believe that people are always rational and well-informed. But I do believe that people have incentives to be rational and well-informed, especially on crucial issues related to their health.

The NBER paper says that given a modest increase in the price of a crucial drug (e.g., a statin), high-risk patients (e.g., with severe arteriosclerosis) will often stop taking the crucial drug, being “unaware of these risks.” I suspect that the policy conclusion that many will draw from the NBER paper is: don’t raise Medicare drug prices.

If the authors are right that high-risk Medicare beneficiaries are clueless, an alternative policy conclusion is: give the beneficiaries a clue.

(p. 7) The high cost of drugs can force some seniors to make difficult choices between paying for medications or other household expenses.

A . . . study by the National Bureau of Economic Research found that when Medicare beneficiaries’ out-of-pocket drug costs jump, there is a significant drop in the number of patients who fill prescriptions and an increase in mortality.

For the full commentary see:

Mark Miller. “Steps for Coping With Medicare’s Rising Costs.” The New York Times, SundayBusiness Section (Sun., December 26, 2021 [sic]): 7.

(Note: ellipsis added.)

(Note: the online version of the commentary has the date Dec. 22, 2021 [sic], and has the title “How to Cope With Medicare’s Rising Costs.”)

A revised version of the National Bureau of Economic Research paper mentioned above is:

Chandra, Amitabh, Evan Flack, and Ziad Obermeyer. “The Health Costs of Cost-Sharing.” National Bureau of Economic Research Working Paper #28439, Feb. 2024.

Gig Work Enables Free Agent Entrepreneurship

In my Openness book, I distinguish between free agent entrepreneurs and innovative entrepreneurs. Free agent entrepreneurs are there own boss, doing what has been done before. Innovative entrepreneurs are their own boss, doing what is new. Of course the distinction is not sharp–a continuum.

Recent research, summarized in the WSJ, suggests that gig work can ease entry into free agent entrepreneurship. Gig work is flexible–the gig worker has time when they need it, to work on their entrepreneurial venture. Gig work also can generate capital and give experience in self-management.

A higher percent of gig workers become entrepreneurs than similar employed workers, and they do so, on average, at a slightly younger age.

Those who want to regulate gig work, and thereby make it less common, should remember how gig work benefits aspiring entrepreneus.

The WSJ article mentioned above is:

Lisa Ward. “Gig Workers Show More Enterprise, Study Finds.” The Wall Street Journal (Thurs., May 8, 2025): A11.

(Note: the online version of the WSJ article has the date May 5, 2025, and has the title “Want to Start a Business? Maybe Begin by Being a Gig Worker.”)

The academic working paper summarized in the WSJ article is:

Denes, Matthew R., Spyridon Lagaras, and Margarita Tsoutsoura. “Entrepreneurship and the Gig Economy: Evidence from U.S. Tax Returns.” In National Bureau of Economic Research Working Paper #33347, Jan. 2025.

My book mentioned in my initial comments is:

Diamond, Arthur M., Jr. Openness to Creative Destruction: Sustaining Innovative Dynamism. New York: Oxford University Press, 2019.

We Need Market-Tested Innovation to Cure the Sadly Chaotic, Inefficient, Dishonest, and Unfair Organ Transplant System

The government contracts with, and ‘supervises,’ a network of nonprofits in a sadly chaotic, inefficient, dishonest, and unfair system to allocate scarce transplant organs. The government has set up perverse incentives, with unintended consequences, by telling the nonprofits that they will be evaluated on the basis of not wasting organs; those evaluated badly will not have their contracts renewed. So they have an incentive to get the organs out the door quickly, even if they do not go to patients higher on the waiting list. Hospitals know they will be evaluated on the basis of how many transplanted patients survive at least a year. So they have an incentive to reject below average organs, and, when they get above average organs, to ignore the waiting list, in order to transplant them into the most healthy patients.

The result is that the sickest and those who have waited the longest are frequently skipped over, instead of receiving the organ when it is their turn.

Why don’t we try something bold–allow for-profit entrepreneurs to engage in medical institutional innovation? For instance, if we allow it, one medical entrepreneurs might purchase from willing donors the right to allocate their organs if and when they become available. Another medical entrepreneur might set up an institution appealing to donors who do not want to be paid, but do want a guarantee that their organs will go to the poor at no charge.

In retailing Walmart and Amazon have different models, but both made major logistical innovations. We need a Walmart and an Amazon of organ transplantation. We need market-tested innovation (as Deirdre McCloskey might say).

Allowing some donors to be paid will reduce the scarcity of organs, which is the most basic constraint on this issue. Innovative medical entrepreneurs may find other ways to loosen this most basic constraint, such as mechanical organs, regrowing human organs from stem cells, and growing transplantable organs in pigs.

(p. A1) For decades, fairness has been the guiding principle of the American organ transplant system. Its bedrock, a national registry, operates under strict federal rules meant to ensure that donated organs are offered to the patients who need them most, in careful order of priority.

But today, officials regularly ignore the rankings, leapfrogging over hundreds or even thousands of people when they give out kidneys, livers, lungs and hearts. These organs often go to recipients who are not as sick, have not been waiting nearly as long and, in some cases, are not on the list at all, a New York Times investigation found.

Last year, officials skipped patients on the (p. A10) waiting lists for nearly 20 percent of transplants from deceased donors, six times as often as a few years earlier. It is a profound shift in the transplant system, whose promise of equality has become increasingly warped by expediency and favoritism.

Under government pressure to place more organs, the nonprofit organizations that manage donations are routinely prioritizing ease over fairness. They use shortcuts to steer organs to selected hospitals, which jockey to get better access than their competitors.

. . .

The Times analyzed more than 500,000 transplants performed since 2004 and found that procurement organizations regularly ignore waiting lists even when distributing higher-quality organs. Last year, 37 percent of the kidneys allocated outside the normal process were scored as above-average. Other organs are not scored in the same way, but donor age is often used as a proxy for quality, and data shows there is little difference in the age of organs allocated normally compared with those that are not.

And while many people in the transplant community believe ignoring lists is reducing organ wastage, there is no evidence that is true, according to an unreleased report by a group of doctors and researchers asked by the transplant system last year to study the practice.

. . .

In 2020, procurement organizations felt under attack. Congress was criticizing them for letting too many organs go to waste. Regulators moved to give each organization a grade and, starting in 2026, fire the lowest performers.

They scrambled to respond. They assigned more staff to hospitals to identify donors, grew more aggressive with families and recovered more organs from older or sicker donors.

Those steps increased donations and transplants, dozens of employees said. Both hit record highs last year, when there were 41,115 transplants.

At the same time, the organizations increasingly used a shortcut known as an open offer. Open offers are remarkably efficient — officials choose a hospital and allow it to put the organ into any patient.

. . .

Some procurement organizations sidestep the list because they believe it helps them place more organs. But it can also help their bottom lines.

In 2021, the South Carolina procurement organization phased out its allocation team and handed the task to workers who were already managing donors, testing organs and helping with surgeries. As a workaround, three former employees said, executives created a spreadsheet with preferred doctors’ phone numbers.

If the employees were too busy to do allocation, they said, they were told to give open offers to those doctors.

“They’d tell me to get rid of the organs quickly, so I could be done,” said Aron Knorr, one of the former workers, who said the directive made him uncomfortable.

. . .

Dr. Alghidak Salama, who led South Florida’s organization until August [2024], said open offers were financially beneficial: When organizations distribute organs, they are paid a set fee by receiving hospitals, regardless of what costs they incur. Speeding up allocation (p. A11) saves money on staffing.

. . .

When hospitals get open offers, they often give organs to patients who are healthier than others needing transplants, The Times found. For example, 80 percent of all donated hearts in recent years went to patients sick enough to be hospitalized, records show. But when lists were skipped, it was less than 40 percent.

Healthier patients are likelier to help transplant centers perform well on one of their most important benchmarks: the percentage of patients who survive a year after surgery. The government monitors that rate, as do insurers, which can decline to pay low-performing hospitals.

. . .

Federal regulators have known since 2022 that more people were being skipped, according to meeting notes obtained by The Times. But until last week, they had done little to address it.

The U.S. Centers for Medicare & Medicaid Services monitors hospitals and procurement organizations. The Health Resources and Services Administration tracks the system overall. But for years, they deferred to UNOS.

Records show that when the system’s oversight committee reviews instances of bypassed patients, it closes more than 99.5 percent of cases without action, usually concluding that the organ was at risk of going to waste. In the last five years, the committee has never gone further than sending “notices of noncompliance,” the mildest action it can take.

“The oversight is almost nonexistent, and that’s been true basically forever,” said Dr. Seth Karp, a Vanderbilt University surgeon who served on the committee, which he noted is largely made up of transplant doctors and procurement officials policing themselves.

For the full story see:

Brian M. Rosenthal, Mark Hansen and Jeremy White. “Organ Transplant System ‘in Chaos’ As Waiting Lists Are Ignored.” The New York Times (Monday, March 10, 2025): A1 & A10-A11.

(Note: ellipses, and bracketed year, added.)

(Note: the online version of the story has the date Feb. 26, 2025, and has the same title as the print version.)