Buffett’s Berkshire Buys More of Dubious DaVita

A case has been made on CNN that DaVita has committed Medicare fraud costing taxpayers many millions of dollars. DaVita has been discussed in previous blog entries on November 30, 2012, May 18, 2013, and June 11, 2013.

(p. 3D) Omaha investor Warren Buffett’s company bought nearly 3.7 million more shares of DaVita Inc. after the dialysis provider reported its earnings . . . [in the first week of November 2013].

Berkshire Hathaway Inc. said in documents filed with the Securities and Exchange Commission on Friday that it owns 35.1 million shares of DaVita.

For the full story, see:
THE ASSOCIATED PRESS. “Berkshire buys 3.7 million more shares of DaVita after report.” Omaha World-Herald (Mon., November 11, 2013): 3D.
(Note: ellipsis and bracketed words added.)

Stem Cells Used to Create Tiny, Simple Human Livers

LiverBudsMadeFromStemCells2013-10-27.jpg “Researchers from Japan used human stem cells to create “liver buds,” rudimentary livers that, when transplanted into mice, grew and functioned.” Source of caption and photo: online version of the NYT article quoted and cited below.

(p. A3) Researchers in Japan have used human stem cells to create tiny human livers like those that arise early in fetal life. When the scientists transplanted the rudimentary livers into mice, the little organs grew, made human liver proteins, and metabolized drugs as human livers do.

They and others caution that these are early days and this is still very much basic research. The liver buds, as they are called, did not turn into complete livers, and the method would have to be scaled up enormously to make enough replacement liver buds to treat a patient. Even then, the investigators say, they expect to replace only 30 percent of a patient’s liver. What they are making is more like a patch than a full liver.
But the promise, in a field that has seen a great deal of dashed hopes, is immense, medical experts said.
“This is a major breakthrough of monumental significance,” said Dr. Hillel Tobias, director of transplantation at the New York University School of Medicine. Dr. Tobias is chairman of the American Liver Foundation’s national medical advisory committee.

For the full story, see:
GINA KOLATA. “Scientists Fabricate Rudimentary Human Livers.” The New York Times (Thurs., July 4, 2013): A3.
(Note: the online version of the story has the date July 3, 2013.)

The research article is:
Takebe, Takanori, Keisuke Sekine, Masahiro Enomura, Hiroyuki Koike, Masaki Kimura, Takunori Ogaeri, Ran-Ran Zhang, Yasuharu Ueno, Yun-Wen Zheng, Naoto Koike, Shinsuke Aoyama, Yasuhisa Adachi, and Hideki Taniguchi. “Vascularized and Functional Human Liver from an iPSC-Derived Organ Bud Transplant.” Nature (July 3, 2013) DOI: 10.1038/nature12271.

Paper Towels Are Better than Air Dryers at Removing Bacteria

Green environmentalists have forced hot air hand dryers on us in many public restrooms. They are slow and noisy and frustrating, and many of us leave the restroom with still-wet hands. But did you also know that by taking away our paper towels, the environmentalists are helping to spread disease? Read the article abstract below:

(p. 791) The transmission of bacteria is more likely to occur from wet skin than from dry skin; therefore, the proper drying of hands after washing should be an integral part of the hand hygiene process in health care. This article systematically reviews the research on the hygienic efficacy of different hand-drying methods. A literature search was conducted in April 2011 using the electronic databases PubMed, Scopus, and Web of Science. Search terms used were hand dryer and hand drying. The search was limited to articles published in English from January 1970 through March 2011. Twelve studies were included in the review. Hand-drying effectiveness includes the speed of drying, degree of dryness, effective removal of bacteria, and prevention of cross-contamination. This review found little agreement regarding the relative effectiveness of electric air dryers. However, most studies suggest that paper towels can dry hands efficiently, remove bacteria effectively, and cause less contamination of the washroom environment. From a hygiene viewpoint, paper towels are superior to electric air dryers. Paper towels should be recommended in locations where hygiene is paramount, such as hospitals and clinics.

Source:
Cunrui, Huang, Ma Wenjun, and Susan Stack. “The Hygienic Efficacy of Different Hand-Drying Methods: A Review of the Evidence.” Mayo Clinic Proceedings 87, no. 8 (Aug. 2012): 791-98.

Beer Was Safer than Water

(p. C24) . . . what would beer be without water? . . . New York City, at least until the opening of the Croton Aqueduct in 1842, had no clean, reliable source. In fact, since hops have a preservative quality, and brewing requires boiling, “beer was once considered safer to drink than water.”

For the full review, see:
EDWARD ROTHSTEIN. “EXHIBITION REVIEW; A Tipple or Two? It Was Safer Than Water.” The New York Times (Fri., May 25, 2012): C19 & C24.
(Note: ellipses added.)
(Note: the online version of the review has the date May 24, 2012.)

Foreign Aid Frees Despots from Having to Seek the Consent of the Governed

TheGreatEscapeBK2013-10-24.jpg

Source of book image: online version of the NYT review quoted and cited below.

(p. 4) IN his new book, Angus Deaton, an expert’s expert on global poverty and foreign aid, puts his considerable reputation on the line and declares that foreign aid does more harm than good. It corrupts governments and rarely reaches the poor, he argues, and it is high time for the paternalistic West to step away and allow the developing world to solve its own problems.

It is a provocative and cogently argued claim. The only odd part is how it is made. It is tacked on as the concluding section of “The Great Escape: Health, Wealth, and the Origins of Inequality” (Princeton University Press, 360 pages), an illuminating and inspiring history of how mankind’s longevity and prosperity have soared to breathtaking heights in modern times.
. . .
THE author has found no credible evidence that foreign aid promotes economic growth; indeed, he says, signs show that the relationship is negative. Regretfully, he identifies a “central dilemma”: When the conditions for development are present, aid is not required. When they do not exist, aid is not useful and probably damaging.
Professor Deaton makes the case that foreign aid is antidemocratic because it frees local leaders from having to obtain the consent of the governed. “Western-led population control, often with the assistance of nondemocratic or well-rewarded recipient governments, is the most egregious example of antidemocratic and oppressive aid,” he writes. In its day, it seemed like a no-brainer. Yet the global population grew by four billion in half a century, and the vast majority of the seven billion people now on the planet live longer and more prosperous lives than their parents did.

For the full review, see:
FRED ANDREWS. “OFF THE SHELF; A Surprising Case Against Foreign Aid.” The New York Times, SundayBusiness Section (Sun., October 13, 2013): 4.
(Note: ellipsis added.)
(Note: the online version of the review has the date October 12, 2013.)

The book reviewed is:
Deaton, Angus. The Great Escape: Health, Wealth, and the Origins of Inequality. Princeton, N.J.: Princeton University Press, 2013.

Gene-Altered Mice Live 20% Longer

MouseGeneAltertedLivesLonger2013-09-27.jpg “NIH researchers found that lowering the expression of a single gene helped extend the life of mice by about 20%. A mouse with a manipulated gene on the right and an unchanged mouse on the left.” Source of caption and photo: online version of the WSJ article quoted and cited below.

(p. A3) By reducing the activity of one type of gene, scientists said they increased the average life span of mice by about 20%, a feat that in human terms is akin to extending life by about 15 years.

Moreover, the researchers at the National Institutes of Health found that memory, cognition and some other important traits were better preserved in the mice as they aged, compared with a control group of mice that had normal levels of a protein put out by the gene.
The findings, published Thursday [August 29, 2013] in the journal Cell Reports, strengthen the case that the gene, called mTOR, is a major regulator of the aging process.
. . .
The results . . . build on a growing body of research challenging the belief that aging is an intractable biological process, prompting scientists to think of slowing aging as a possible way to prevent disease.
“What we need right now is for scientists and the public to wake up to the concept that you can slow aging,” said Brian Kennedy, president of the Buck Institute for Aging Research in Novato, Calif., who wasn’t involved in the new study. “If you do, you prevent many of the diseases that we’re so scared of and that are associated with aging.” They include cardiovascular disease, cancer and Alzheimer’s disease.

For the full story, see:
RON WINSLOW. “Altered Gene Points Toward Longer Life Spans; Successful Experiment With Mice May One Day Play Role in Slowing Human Aging; Side Effects Could Be Problematic.” The Wall Street Journal (Fri, August 30, 2013): A3.
(Note: ellipsis, and bracketed date, added.)
(Note: the online version of the story has the date August 29, 2013, and has the title “Genetic Manipulation Extends Life of Mice 20%; But Translating Findings to Humans Faces Many Hurdles.”)

The scientific article being discussed above, is:
Wu, J.  Julie, Jie Liu, Edmund B Chen, Jennifer J Wang, Liu Cao, Nisha Narayan, Marie M Fergusson, Ilsa I Rovira, Michele Allen, Danielle A Springer, Cory U Lago, Shuling Zhang, Wendy DuBois, Theresa Ward, Rafael deCabo, Oksana Gavrilova, Beverly Mock, and Toren Finkel. “Increased Mammalian Lifespan and a Segmental and Tissue-Specific Slowing of Aging after Genetic Reduction of mTor Expression.” Cell Reports 4, no. 5 (Aug. 29, 2013): 913-20.

Salt May NOT Be Bad for Our Health, After All

(p. A7) An influential government panel said there is no evidence that very low-salt diets prevent heart disease, calling into question current national dietary guidelines on sodium intake.
The Institute of Medicine, in a report released Tuesday [May 14, 2013], said there isn’t sufficient evidence that cutting sodium intake below 2,300 milligrams per day cuts the risk of heart disease. The group of medical experts also said there is no evidence that people who already have heart disease or diabetes should cut their sodium intake even lower.

For the full story, see:
JENNIFER CORBETT DOOREN. “U.S. NEWS; Low-Salt Benefits Questioned.” The Wall Street Journal (Weds., May 15, 2013): A7.
(Note: bracketed date added.)
(Note: the online version of the story has the date May 14, 2013.)

For a summary of the Institute of Medicine report, see:
Institute of Medicine of the National Academies. “Sodium Intake in Populations: Assessment of Evidence.” Report Brief. Washington, D.C.: National Academy of Sciences, 2013.

Hunter-Gatherers Had High Child Mortality and Died Before Age 40

(p. 31) Child mortality in foraging tribes was severe. A survey of 25 hunter-gatherer tribes in historical times from various continents revealed that, on average, 25 percent of children died before they were 1, and 37 percent died before they were 15. In one traditional hunter-gatherer tribe, child mortality was found to be 60 percent. Most historical tribes had a population growth rate of approximately zero. This stagnation is evident, says Robert Kelly in his survey of hunting-gathering peoples, because “when formerly mobile people become sedentary, the rate of population growth increases.” All things being equal, the constancy of farmed food breeds more people.
While many children died young, older hunter-gatherers did not have (p. 32) it much better. It was a tough life. Based on an analysis of bone stress and cuts, one archaeologist said the distribution of injuries on the bodies of Neanderthals was similar to that found on rodeo professionals–lots of head, trunk, and arm injuries like the ones you might get from close encounters with large, angry animals. There are no known remains of an early hominin who lived to be older than 40. Because extremely high child mortality rates depress average life expectancy, if the oldest outlier is only 40, the median age was almost certainly less than 20.

Source:
Kelly, Kevin. What Technology Wants. New York: Viking Adult, 2010.

The French and Japanese Believe Water Cleans the Anus Better than Dry Paper

TheBigNecessityBK2013-07-21.jpg

Source of the book image: http://jacketupload.macmillanusa.com/jackets/high_res/jpgs/9780805090833.jpg

(p. C34) Ms. George’s book is lively . . . . It is hard not to warm to a writer who can toss off an observation like this one: “I like engineers. They build things that are useful and sometimes beautiful — a brick sewer, a suspension bridge — and take little credit. They do not wear black and designer glasses like architects. They do not crow.”
. . .
In Japan, where toilets are amazingly advanced — most of even the most basic have heated seats and built-in bidet systems for front and rear — the American idea of cleaning one’s backside with dry paper is seen as quaint at best and disgusting at worst. As Ms. George observes: “Using paper to cleanse the anus makes as much sense, hygienically, as rubbing your body with dry tissue and imagining it removes dirt.”

For the full review, see:
DWIGHT GARNER. “BOOKS OF THE TIMES; 15 Minutes of Fame for Human Waste and Its Never-Ending Assembly Line.” The New York Times (Fri., December 12, 2008): C34.
(Note: ellipses added.)
(Note: the online version of the review has the date December 11, 2008.)

The book under review, is:
George, Rose. The Big Necessity: The Unmentionable World of Human Waste and Why It Matters. New York: Metropolitan Books, 2008.

The Precautionary Principle Is Biased Against the New, and Ignores the Risks of the Old

(p. 250) In general the Precautionary Principle is biased against anything new. Many established technologies and “natural” processes have unexamined faults as great as those of any new technology. But the Precautionary Principle establishes a drastically elevated threshold for things that are new. In effect it grandfathers in the risks of the old, or the “nat-(p. 251)ural.” A few examples: Crops raised without the shield of pesticides generate more of their own natural pesticides to combat insects, but these indigenous toxins are not subject to the Precautionary Principle because they aren’t “new.” The risks of new plastic water pipes are not compared with the risks of old metal pipes. The risks of DDT are not put in context with the old risks of dying of malaria.

Source:
Kelly, Kevin. What Technology Wants. New York: Viking Adult, 2010.

Millions Die Due to Precautionary Principle Ban of DDT

(p. 248) . . . , malaria infects 300 million to 500 million people worldwide, causing 2 million deaths per year. It is debilitating to those who don’t die and leads to cyclic poverty. But in the 1950s the level of malaria was reduced by 70 percent by spraying the insecticide DDT around the insides of homes. DDT was so successful as an insecticide that farmers eagerly sprayed it by the tons on cotton fields–and the molecule’s by-products made their way into the water cycle and eventually into fat cells in animals. Biologists blamed it for a drop in reproduction rates for some predatory birds, as well as local die-offs in some fish and aquatic life species. Its use and manufacture were banned in the United States in 1972. Other countries followed suit. Without DDT spraying, however, malaria cases in Asia and Africa began to rise again to deadly pre-1950s levels. Plans to reintroduce programs for household spraying in malarial Africa were blocked by the World Bank and other aid agencies, who refused to fund them. A treaty signed in 1991 by 91 countries and the EU agreed to phase out DDT altogether. They were relying on the precautionary principle: DDT was probably bad; better safe than sorry. In fact DDT had never been shown to hurt humans, and the environmental harm from the miniscule amounts of DDT applied in homes had not been measured. But nobody could prove it did not cause harm, despite its proven ability to do good.

Source:
Kelly, Kevin. What Technology Wants. New York: Viking Adult, 2010.
(Note: ellipsis added.)