The Secret to a Long Life Is Conscientiousness

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Source of book image: online version of the NYT review quoted and cited below.

(p. D3) Cheerfulness, optimism, extroversion and sociability may make life more enjoyable, but they won’t necessarily extend it, Howard S. Friedman and Leslie R. Martin found in a study that covered eight decades. The key traits are prudence and persistence. “The findings clearly revealed that the best childhood personality predictor of longevity was conscientiousness,” they write, “the qualities of a prudent, persistent, well-organized person, like a scientist-professor — somewhat obsessive and not at all carefree.”
. . .
There are three explanations for the dominant role of conscientiousness. The first and most obvious is that conscientious people are more likely to live healthy lifestyles, to not smoke or drink to excess, wear seat belts, follow doctors’ orders and take medication as prescribed. Second, conscientious people tend to find themselves not only in healthier situations but also in healthier relationships: happier marriages, better friendships, healthier work situations.
The third explanation for the link between conscientiousness and longevity is the most intriguing. “We thought it must be something biological,” Dr. Friedman said. “We ruled out every other factor.” He and other researchers found that some people are biologically predisposed to be not only more conscientiousness but also healthier. “Not only do they tend to avoid violent deaths and illnesses linked to smoking and drinking,” they write, “but conscientious individuals are less prone to a whole host of diseases, not just those caused by dangerous habits.” The precise physiological explanation is unknown but seems to have to do with levels of chemicals like serotonin in the brain.
As for optimism, it has its downside. “If you’re cheerful, very optimistic, especially in the face of illness and recovery, if you don’t consider the possibility that you might have setbacks, then those setbacks are harder to deal with,” Dr. Martin said. “If you’re one of those people who think everything’s fine — ‘no need to back up those computer files’ — the stress of failure, because you haven’t been more careful, is harmful. You almost set yourself up for more problems.”

For the full review, see:
KATHERINE BOUTO. “BOOKS ON SCIENCE; Eighty Years Along, a Longevity Study Still Has Ground to Cover.” The New York Times (Tues., April 19, 2011): D3.
(Note: ellipsis added.)
(Note: the online version of the article is dated April 18, 2011.)

The book under review is:
Friedman, Howard S., and Leslie R. Martin. The Longevity Project: Surprising Discoveries for Health and Long Life from the Landmark Eight-Decade Study. New York: Hudson Street Press, 2011.

Feds Finally Admit Some Children Harmed by High Fluoridated Water Mandates

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WSJ article quoted and cited below.

Back when I was a child, decades ago, my family opposed the fluoridation of public water supplies on the grounds that there might be health risks, and people could individually choose to apply fluoride to their teeth.
Well, now the government is suggesting that too much fluoride can harm children’s teeth, and that the target level for fluoride in the water should be reduced.

(p. A3) The federal government lowered its recommended limit on the amount of fluoride in drinking water for the first time in nearly 50 years, saying that spots on some children’s teeth show they are getting too much of the mineral.

Fluoride has been added to U.S. water supplies since 1945 to prevent tooth decay. Since 1962, the government has recommended adding a range of 0.7 milligrams to 1.2 milligrams per liter.
. . .
A study conducted between 1999 and 2004 by the federal Centers for Disease Control and Prevention found that 41% of children between the ages of 12 and 15 exhibited signs of dental fluorosis, a spotting or streaking on the teeth. That was up from nearly 23% found in a study from 1986 and 1987.
. . .
. . . for years, some groups have called for an end to fluoridation, arguing that it poses serious health dangers, including increased risk of bone fractures and of decreased thyroid function. Friday’s announcement did little to appease such critics.
“The only rational course of action is to stop water fluoridation,” said Paul Connett, executive director of the Fluoride Action Network, a nonprofit advocacy and fluoride-education group

.

For the full story, see:
TIMOTHY W. MARTIN. “Government Advises Less Fluoride in Water.” The Wall Street Journal (Sat., JANUARY 8, 2011): A3.
(Note: ellipses added.)

Patients Face Higher Costs and Less Innovation Due to FDA

CongerMartiDiskImplant2011-05-16.jpg“Marti Conger, a business consultant in Benicia, Calif., went to England in October 2009 to get an implant of a new artificial disk for her spine developed by Spinal Kinetics of Sunnyvale, Calif., a short distance from her home.” Source of caption and photo: online version of the NYT article quoted and cited below.

(p. B1) Late last year, Biosensors International, a medical device company, shut down its operation in Southern California, which had once housed 90 people, including the company’s top executives and researchers.

The reason, executives say, was that it would take too long to get its new cardiac stent approved by the Food and Drug Administration.
“It’s available all over the world, including Mexico and Canada, but not in the United States,” said the chief executive, Jeffrey B. Jump, an American who runs the company from Switzerland. “We decided, let’s spend our money in China, Brazil, India, Europe.”
. . .
(p. B7) “Ten years from now, we’ll all get on planes and fly somewhere to get treated,” said Jonathan MacQuitty, a Silicon Valley venture capitalist with Abingworth Management.
Marti Conger, a business consultant in Benicia, Calif., already has. She went to England in October 2009 to get an implant of a new artificial disk for her spine developed by Spinal Kinetics of Sunnyvale, Calif.
“Sunnyvale is 40 miles south of my house,” said Ms. Conger, who has become an advocate for faster device approvals in the United States. “I had to go to England to get my surgery.”
. . .
Device companies have been seeking early approval in Europe for years because it is easier. In Europe, a device must be shown to be safe, while in the United States it must also be shown to be effective in treating a disease or condition. And European approvals are handled by third parties, not a powerful central agency like the F.D.A.
But numerous device executives and venture capitalists said the F.D.A. has tightened regulatory oversight in the last couple of years. Not only does it take longer to get approval but it can take months or years to even begin a clinical trial necessary to gain approval.
Disc Dynamics made seven proposals over three years but could not get clearance from the F.D.A. to conduct a trial of its gel for spine repair, said David Stassen, managing partner of Split Rock Partners, a venture firm that backed the company. “It got to the point where the company just ran out of cash,” Mr. Stassen said. Disc Dynamics was shut down last year after an investment of about $65 million.

For the full story, see:
ANDREW POLLACK. “Medical Treatment, Out of Reach.” The New York Times (Thurs., February 10, 2011): B1 & B7.
(Note: ellipses added.)
(Note: the online version of the story is dated February 9, 2011.)

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“An artificial disk like the one Marti Conger received.”
Source of caption and photo: online version of the NYT article quoted and cited above.

Mexican Universal Health Care: “There Are No Doctors, No Medicine, No Hospital Beds”

(p. 6) A decade ago, half of all Mexicans had no health insurance at all. Then the country’s Congress passed a bill to ensure health care for every Mexican without access to it. The goal was explicit: universal coverage.

By September, the government expects to have enrolled about 51 million people in the insurance plan it created six years ago — effectively reaching the target, at least on paper.
The big question, critics contend, is whether all those people actually get the health care the government has promised.
. . .
The money goes from the federal government to state governments, depending on how many people each state enrolls. From there, it is up to state governments to spend the money properly so that patients get the promised care.
That, critics say, is the plan’s biggest weakness. State governments have every incentive to register large numbers, but they do not face any accountability for how they spend the money.
“You have people signed up on paper, but there are no doctors, no medicine, no hospital beds,” said Miguel Pulido, the executive director of Fundar, a Mexican watchdog group that has studied the poor southern states of Guerrero and Chiapas.
Mr. Chertorivski acknowledges that getting some states to do their work properly is a problem. “You can’t do a hostile takeover,” he said.
The result is that how Mexicans are treated is very much a function of where they live. Lucila Rivera Díaz, 36, comes from one of the poorest regions in Guerrero. She said doctors there told her to take her mother, who they suspected had liver cancer, for tests in the neighboring state of Morelos.

For the full story, see:
ELISABETH MALKIN. “Mexico Struggles to Realize the Promise of Universal Health Care.” The New York Times, First Section (Sun., January 30, 2011): 6.
(Note: the online version of the story is dated January 29, 2011 and has the title “Mexico’s Universal Health Care Is Work in Progress.”)
(Note: ellipsis added.)

Nanotechnology Zaps Dangerous Superbug

MRSAcellBeforeNanoZap2011-04-25.jpg “A MRSA cell before treatment with nanoparticles.” Source of caption and photo: online version of the WSJ article quoted and cited below.

(p. A3) Researchers at International Business Machines Corp. said they developed a tiny drug, called a nanoparticle, that in test-tube experiments showed promise as a weapon against dangerous superbugs that have become resistant to antibiotics.

The company’s researchers, in collaboration with scientists at the Institute of Bioengineering and Nanotechnology, Singapore, said their nanoparticle can target and destroy antibiotic-resistant bacteria–such as the potentially lethal Methicillin-resistant Staphylococcus aureus, or MRSA–without affecting healthy cells.
. . .
IBM, based in Armonk, N.Y., has been working for decades on nanotechnology, which involves engineering atomic-scale particles and electronics. Recently the company has applied those principles–used to create tiny, fast semiconductors–into new areas such as water purification and recyclable plastics. It’s now applying those principles to medicine.
“It turns out that we’ve discovered a lot of ways to control materials at the molecular level as we went through building microelectronic devices,” Dr. Hedrick said.

For the full story, see:

RON WINSLOW And SHARA TIBKEN. “Big Blue’s Tiny Bug Zapper; IBM Researchers Develop Nanoparticle to Destroy Antibiotic-Resistent Bacteria.” The Wall Street Journal (Mon., APRIL 4, 2011): A3.

(Note: ellipsis added.)

MRSAcellAfterNanoZap2011-04-25.jpg“What’s left of the cell after getting zapped.” Source of caption and photo: online version of the WSJ article quoted and cited above.

45% of Mummies Had Heart Disease

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“A mummy enters the CT scanner at St. Luke’s Hospital in Kansas City, Mo. It was one of 52 mummies examined for signs of heart disease.” Source of caption and photo: online version of the Omaha World-Herald article quoted and cited below.

(p. 6A) Atherosclerosis — hardening of the arteries — was surpris­ingly widespread during an­cient times, at least among the Egyptian mummies examined by an international team of sci­entists and heart specialists.

Their research, whose re­sults were presented April 3 in New Orleans at the annual meeting of the American Col­lege of Cardiology, found that 45 percent of the mummies they put through CT scans had signs of atherosclerosis.
That raises questions about whether hardening of the arter­ies is the modern disease that many think it is.
“We found it so easily and frequently that it appears to have been common in this soci­ety,” said Randall Thompson, a cardiologist at St. Luke’s Hospi­tal in Kansas City.

For the full story, see:
MC CLATCHY NEWSPAPERS. “Hardened Arteries Go Back Centuries.” Omaha World-Herald (Mon., April 18, 2011): 6A.

The Elite Feel More Important, and Receive More Funding, During Crises

(p. 103) Claims of disastrous decline will he praised in the elite parts of society. Since many crave recognition or rewards from elites, people oblige by producing claims of disastrous decline. More generally, when things really are bad we naturally turn to eminent or powerful people for their advice and succor; when things are fine, the elite classes are of diminished importance to society. Important people like to feel important, and thus are biased toward viewing events in bleak terms. Consider that, during the 1990s, when nearly everything in the United States was trending positive, left-wing leaders as exemplified by the Manhattan chardonnay circuit, and right-wing leaders as exemplified by the Heritage Foundation circuit, slugged it out as though the world was ending: the left claiming religious fanatics were taking over the country, the right claiming the left was destroying the family and opposed to reading of the classics, to name a few totally cooked-up charges of that period. As Orlando Patterson, a Harvard University sociologist, noted in 1998, “It’s astonish-(p. 104)ing how the Washington and New York elites, who benefit so much from the improvement of the United States, are so out of sync with it, endlessly talking about how things are getting worse when the country is clearly improving.”

To those who benefit from bad news, either by fund-raising or increased self-importance, problems are not just problems but crises–the health care crisis, the farm-bill crisis, the tax crisis, the welfare crisis, the litigation crisis, the postage-rate crisis.

Source:
Easterbrook, Gregg. The Progress Paradox: How Life Gets Better While People Feel Worse. Paperback ed. New York: Random House, 2004.

To Paul Ryan, More Market Incentives in Health Care Would Reduce Costs and Improve Care

(p. B1) . . . Medicare’s long-term funding gap — . . . is by far the biggest source of looming federal deficits.

. . .
(p. B13) Some health economists believe that a combination of higher taxes and more Medicare cost controls can solve the problem. Mr. Ryan does not. And his skepticism is healthy.
To him, the only way to reduce Medicare’s cost growth is to stop shielding people from the consequences of their decisions. If they want almost limitless medical treatments, they won’t be able to foist the bill on taxpayers, as they do now. They will instead have to buy a generous insurance plan, partly with their own money. The resulting market forces, Mr. Ryan argues, will eventually bring down costs and leave most people better off.

For the full story, see:
DAVID LEONHARDT. “Economic Scene; A Lopsided Proposal for Medicare.” The New York Times (Weds., April 6, 2011): B1 & B13.
(Note: ellipses added.)
(Note: the online version of the article is dated April 5, 2011 and has the title “Economic Scene; Generational Divide Colors Debate Over Medicare’s Future.”)

Father of Cornhusker Kickback Is Named “2010 Porker of the Year”

(p. 6A) Sen. Ben Nelson can’t shake the “Cornhusker Kickback.”
This week, a government watchdog group named the Nebraska Democrat its “2010 Porker of the Year,” based on an online poll.
Citizens Against Government Waste included Nelson in the poll, citing his role negotiating a pro­vision of the federal health care bill that would have exempted Nebraska from paying the added costs of the law’s expanded Med­icaid coverage. That provi­sion was later dropped in fa­vor of relief for all states, which Nelson has said was his goal all along.
Nelson cast the decisive 60th vote for the bill in late 2009.
. . .
Mark Fahleson, chairman of the Nebraska Republican Party, said Nelson was trying to rewrite history. “The fact is he’s the fa­ther of the Cornhusker Kick­back,” he said.

For the full story, see:
MICHAEL O’CONNOR. “Nelson rejects group’s ‘Porker of Year’ label.” Omaha World-Herald (Fri., March 4, 2011): 6A.
(Note: ellipsis added.)

The Dangers from Disease Are Much Greater than the Dangers from Vaccines

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Source of book image:
http://blogs.plos.org/takeasdirected/files/2011/02/Offit-Deadly-Choices1.jpg

Sometime during the weekend of Feb. 26-27, 2011, I saw several minutes of a C-Span book TV presentation by Paul Offit on his Deadly Choices book. He made a strong case that based on casual and unsound evidence, many parents are putting their children at risk by delaying or even foregoing having their children vaccinated.
As a result children are dying from diseases that they easily could have been protected against.

Book discussed:
Offit, Paul A. Deadly Choices: How the Anti-Vaccine Movement Threatens Us All. New York: Basic Books, 2011.

“Powerful Pressure for Scientists to Conform”

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Source of book image: online version of the WSJ review quoted and cited below.

(p. A13) In “Hyping Health Risks,” Geoffrey Kabat, an epidemiologist himself, shows how activists, regulators and scientists distort or magnify minuscule environmental risks. He duly notes the accomplishments of epidemiology, such as uncovering the risks of tobacco smoking and the dangers of exposure to vinyl chloride and asbestos. And he acknowledges that industry has attempted to manipulate science. But he is concerned about a less reported problem: “The highly charged climate surrounding environmental health risks can create powerful pressure for scientists to conform and to fall into line with a particular position.”

Mr. Kabat looks at four claims — those trying to link cancer to man-made chemicals, electromagnetic fields and radon and to link cancer and heart disease to passive smoking. In each, he finds more bias than biology — until further research, years later, corrects exaggeration or error.
. . .
I know whereof Mr. Kabat speaks. In 1992, as the producer of a PBS program, I interviewed an epidemiologist who was on the EPA’s passive-smoking scientific advisory board. He admitted to me that the EPA had put its thumb on the evidentiary scales to come to its conclusion. He had lent his name to this process because, he said, he wanted “to remain relevant to the policy process.” Naturally, he didn’t want to appear on TV contradicting the EPA.

For the full review, see:
RONALD BAILEY. “Bookshelf; Scared Senseless.” The Wall Street Journal (Mon., AUGUST 11, 2008): A13.
(Note: ellipsis added.)
(Note: the first paragraph quoted above has slightly different wording in the online version than the print version; the second paragraph quoted is the same in both.)

The book under review is:
Kabat, Geoffrey C. Hyping Health Risks: Environmental Hazards in Daily Life and the Science of Epidemiology. New York: Columbia University Press, 2008.